Description

Summary: Identified coding regions with a very low synonymous substitution rate Ð indicating additional sequence constraints beyond the amino acid level. The Synonymous Constraint Elements (SCEs) are defined at three different resolutions (9-, 15-, and 30-codon). There is also a bedGraph track for the local estimate of the synonymous substitution rate (lambda_s). Also available at: http://compbio.mit.edu/SCE/^M ^M File: SynonymousConstraintElements.tar.gz^M Files in archive: ^M SCE9.hg18.bed.gz^M SCE15.hg18.bed.gzSCE30.hg18.bed.gz^M lambda_s_ORF.hg18.bedGraph.gz^M File formats: BED, bedGraph^M Format note: coordinates are on hg18^M ^M

Credits

Contact: Mike Lin ^M

References