PRDM11: giant missing exon
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Revision as of 18:46, 11 December 2011 by Tomemerald (talk | contribs) (Created page with "=== PRDM11 reference sequences === The reference sequence for the human gene PRDM11 is wrong in two respects: translating a segment of 5'UTR and running out into a stop codon ra...")
PRDM11 reference sequences
The reference sequence for the human gene PRDM11 is wrong in two respects: translating a segment of 5'UTR and running out into a stop codon rather than splicing to the large terminal exon:
>PRDM11_homSap Homo sapiens (human) original refSeq 511 aa model not supported PhosS 3RAY coverage knuckle SET 0 MLKMAEPIASLMIVECRACLRCSPLFLYQREK 0 0 DRMTENMKECLAQTNAAVGDMVTVVKTEVCSPLRDQEYGQPC 2 1 SRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNRYKSIDGSDETKANWMR 2 1 YVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLAR 1 2 GEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFSDPAGKLVWMRLLSEGRVRSGLCGG* 0
The sequences below use a gene model of human PRDM11 consistent with transcript data and vertebrate comparative genomics. The coding regions consists of seven exons and 1233 total amino acids, including the second largest exon in the entire proteome (722 amino acids). An early serine is post-translationally modified to phosphoserine (according to its UniProt entry Q9NQV5). There are four domains conserved in all species: an early zinc knuckle, a PR(SET) methylation domain, a ZNF_TTF transcription factor zinc finger and a distal hATC dimerization domain. All species containing the gene have these four domains and the same introns. However, it cannot be traced back earlier than rayfinned fish.
>PRDM11_homSap Homo sapiens (human) corrected 511+722 aa 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization no early zinc finger or terminal array syn PFM8 related ZNF 862 0 MTENMKECLAQTNAAVGDMVTVVKTEVCSPLRDQEYGQPC 2 1 SRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNRYKSIDGSDETKANWMR 2 1 YVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLAR 1 2 GEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFSDPA 1 2 ASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSVILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAF SALGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTAATLCEETEFLGDIRAVRWIIGEQN VLNALIKDYLEVVAHLKEVSSQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYIFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAMKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRIFVKACQVFDLAAWPRSSEELMSYGKEDMVQIFDHLEAIPTFSRDVCREGLDPRGSLLMEWRELKADYYTKNGFKDLISHICKYKQRFPLLNK IIQVLKVLPTSTACCEKGRNALQRVRKNHRSRLTLEQLSDLLTIAVNGPPITNFDAKRALDSWFEEKSGNSYALSAEVLSRMSALEQKPALQTMDHGTEFYPDI* 0 >PRDM11_musMus Mus musculus (mouse) blat 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MTENMKECLAHTKAAVGDMVTVVKTEVCSPLRDQEYGQPC 2 1 SRRLEPSSMEVEPKKLKGKRDLIVTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDAGGESDVRCINEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNRYKSIDGSDETKANWMR 2 1 YVVISREEREQNLLAFQHSERIYFRACRDIRPGERLRVWYSEDYMKRLHSMSQETIHRNLAR 1 2 GEKRLQREKAEQALENPEDLRGPTQFPVLKQGRSPYKRSFDEGDIHPQAKKKKIDLIFKDVLEASLESGNVEARQLALSTSLVIRKVPKYQDDDYGRAALTQGICRTPGEGDWKVPQRVAKELGPLEDEEEEPTSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPSLLPPQVLELPEFSDPA 1 2 ASESMVSGPAIMEDDDQEVDSADESVSNDVMTATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAF AALGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRWIIGEQN VLNALIKDYLEVVAHLKDVSSQTQRADASAIALALLQFLMDYQSMKLIYFLLDVIAVLSRLAYIFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRVFVKACQVFDLAAWPRNSEELLSFGKEDMVQIFDHLEAIPAFSRDVCREGTDPRGSLLMEWRDLKADYYTKNGFKDLLSHICKYKQRFPLLNK IIQVLKVLPTSTACCEKGRSALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIANFDAKRALDSWFEEKSGNSYTLSAEVLSRMSALEQKPMLHVVDHGSEFYPDM* 0 >PRDM11_canFam Canis familiaris (dog) blat 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MTENMKECLAQTKAAVGDMVTVVKTEVYSPLRDQEYGQPC 2 1 SRRPDPSTMEVEPKKLKGKRELIMPKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKEASGENDVRCINEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNRYKSIDGSDETKANWMR 2 1 YVVISREEREQNLLAFQHSERIYFRACRDIRPGERLRVWYSEDYMKRLHSMSQETIHHNLAR 1 2 GEKRLQREKSEQALDNPEDLRGPIQLPVLRQGKSPYKRGFDEGDAHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKYQDDAYSRCAMTMSHGVQNVSRTQGEGDWKIPQGASKEPGPLEDEEEEPSSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPAQVLELPEFSDPA 1 2 ASESMVSGPAIMEDDDQEVDSADESVSNDMLTAADEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAF SALGIRLQDEKPTVGLGIDGANVTASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRWIIGEQN VLNALIKDYLEVVAHLKDVSSQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAMKNLRVAE AKFQSVREKICQKTQVILAQRFDSRSRIFVKACQVFDLAAWPRSSEELMSYGKEDMVQIFDHLEAIPTFSRDVCREGLDPRGSLLMEWRELKADYYTKNGFKDLIGHICKYKQRFPLLNK IIQVLKVLPTSTACCEKGRNALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIANFDAKRALDSWFEEKSGNSYALSAEVLSRMSALEQKPVLQTVDHGSEFYPDI* 0 >PRDM11_loxAfr Loxodonta africana (elephant) blat 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MTENMKECLAKTKAAVGDMVPVVKTEVCSPLHDQEYGQPC 2 1 SRRPDPSAMDVEPKKLKGKRDLIMPKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKEASGENDVRCISEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNRYKSVDGSDETKANWMR 2 1 YVVISREEREQNLLAFQHSERIYFRVCRDIRPGERLRVWYSQDYMKRLHSMSQETIHRNLAR 1 2 GEKRLQREKSEQALDNPEDLRGSIQLPVLRQGKSPYKRGFDEGDLHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKYQDDTYSRCATTMSHGVQNVSRTQGEGDWKIPQGASKEPGPTEDEEEEPSSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPAQVLELPEFSDPA 1 2 ASESMVSGPAIMEDDDQEVDSADESVSNDIMTATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSGTESYLQALDRAF STLGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDISSQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAMKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRIFVKACQVFDLAAWPRSSEELVSYGKEDMVQIFDHLEAIPTFSRDVCREGLDPRGSLLMEWRELKADYYTKNGFKDLISHVGKYKQRFPLLNK IIQILKVLPTSTVCCEKGRNALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIANFDAKRALDSWFEEKSGHSYTLSAEVLSRMSALEQKPVLQAIDHGTEFYPDI* 0 >PRDM11_monDom Monodelphis domestica (opossum) blat 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MTENLKACLAHTQASMGEMVTVKTEVCSPRRDQEYGQPW 2 1 SGRPDPPSMEVEPKKPKGKRELIMTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPMGIPDRAALTIPPGMEVVKEASGQSDVRCMNEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNHYKSIDGTDETKANWMR 2 1 YVVISREEREQNLMAFQHSEKIYFRVCRDIRPGERLRVWYSEDYMKRLHSMSQETIQRNLTR 1 2 GDKKLQREKPEKALDHQEDLRGPLQLTVLRHGKSAYKRGFDEVDAHPPPKKKKIDLIFKDVLEASLETSKIEEHPLAPGTPLVLRKAPKFHTEDVYDQCGMAISHGPQDLSRNQGEKEWKAPQGASYGPSKDTSLLEDEEEEPSSFKADSPAEASLASDLHELPTTSFCPNCIRLKKKIRELQAELDMLKSGKLPEPPLLPPQVPELPEFSDPT 1 2 ASESVVSVPTMLEDDDQEVDSADESVSNEMITATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDILADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTASTLCEETEFLGDIRAVRWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYIFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGVAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTEELMSYGKEDMIQIFDHLETIPSFSREICREGMDPRGSLLMEWRELKADYYTKNGFKDLISHICKYKQRFPLLNKI IQILKVLPTSTACCEKGRVALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDAKRALDSWFEEKSGNSYTLSAEVLSRMSALDQKPMLPTMDHGSEFYSDL* 0 >PRDM11_ornAna Ornithorhynchus anatinus (platypus) blat 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MTENLKDCLAQTQASMGEMVTV KTEVCSPHRDQEYGQPW 2 1 SGRPDPSSMEVEPKKLKGKRDLIMSKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEASGENDVRCMNEVIPKGHIFGPYEGQISTQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YIVISREEREQNLLAFQHSERIYFRVCRDIRPGERLRVWYSEDYMKRLHSMSQETIHRNLTR 1 2 GEKKLLREKTDKAPESQEDLRGPLQLTVLKQGKSPYKRSCDEGDAHPQTKKKKIDLIFKDVLEASLESAKIDEHQLATSTPLAFKKMPKFQAEDVFERCGAILPHGTQSFGRTHSEGDWKLGHGTPYGPSKEKGLLEEDQGEPSPIKVDSPTEASLTGDSQELPTTSFCPNCIRLKKKIRELQAELDMLKSGQLPEPPLVPPQVPELPEFSDPA 1 2 ASESLVSIPTILEDDDPEVDSADESVSNDMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF AALGVRLQDEKPTVGLGVDGANVTASLRAGMFMTVRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTAATLCEETEFLGDIRAVRWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGVAVKNLRVAE AKFQSIREKICQKAQVILAQRFDSRSRTFVKACQVFDLAAWPRSSEELVSYGREDMVQILEHLEAIPSFSREVCREGADPRGALLTEWRELKADYYTKNGFKDLIGHVGKYKQRFPLLNK VIQILKVLPTSTACCEKGRSALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIAHFDAKRALDSWFEEKSGNSYALSAEVLSRMSSLDQKPMLQSVDHGSEFYPDM* 0 >PRDM11_allMis Alligator mississippiensis (alligator) scaffold:58581 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MSENLKDCLIQTQTSLGEMVTIKTEACSPHRDQEYGQPC 2 1 SGRPDPQSMEIEPKKLKGKRDLIMTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRASLTIPPGMEVVKEPNGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YVIISREEREQNLMAFQHSERIYFRTCRDIRPGERLRVWYSEDYMKRLHSMSQETINRNLTR 1 2 GDKKSQREKSEKNMENQEDMRGPLQLTTLKQGKSPYKRSCEEAESHPQTKKKKIDLIFKDVLEASLESAKLEEHQLTTSTPLSIRKASKYQTEDVFERCGTTIQHSSPNLSRNRSEGEWKVPHSSSFSTAKEMGLLEDEEEEPLSLKADSPTEPSLASTQGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEQPALAPQVPELQEFSDPT 1 2 ASESIISVPTIMEDDDQEVDSADESVSNDMIAATDEPSKMSSVTGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPKLMCELRVTAATLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTEELMSYGKEDMVQIFEHLETVPSFSREVCREGMDIRGSLLMEWRELKVDYYTKNGFKDLLGHICKYKQRFPLLNK IVQILKVLPTSSACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPAIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSMDHGSEFYPDI* 0 >PRDM11_galGal Gallus gallus XM_421099 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MSENLKDCLNQTQASLGEMVTIKTEACSPHRDQEYGQPC 2 1 SGRLDPQSMDVEPKKLKGKRDLIMTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YVIISREEREQNLMAFQHSERIYFRACRDIRPGEKLRVWYSEDYMKRLHSMSQETINRNLTT 1 2 GDKKLQKEKSEKNADNQEDTRAPLHFTTLKQGKSPYKRSYDEGESHPQTKKKKIDLIFKDVLEASLESAKFEEKQLATSTPLSTRATSKYQAEEIFERCSSAMQHGSLNLSRNRSEEEWKAPHGSSFSSAKEVGVLEDEEEEPLSLKADSPTELSLASAEGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEPPVLPPQVPELQEFSDPT 1 2 ASESIISVPTIMEDDDQEVDSADESVSNEMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTQGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNK IVQILKVLPTSSACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSVDHGSEFYPDI* 0 >PRDM11_melGal Meleagris gallopavo (turkey) blat/XM_003206406 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MSENLKDCLNQTQASLGEMVTIKTEACSPHQDQEYGQPC 2 1 SGRPDPQSMDVEPKKLKGKRDLIMTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YVIISREEREQNLMAFQHSERIYFRACRDIRPGEKLRVWYSEDYMKRLHSMSQETINRNLTT 1 2 GDKKLQKEKSEKNTDNQEDTRGPLQFTMLKQGKSPYKRSYDEGESHPQTKKKKIDLIFKDVLEASLESAKFEEKQLATSTPLSTRATSKYQAEEIFERCSGAMQHLSRNRSEEEWKAPHGSSLSSAKEVGVLEDEEEEPLSLKADSPTELSLASAEGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEPSVLPPQVPELQEFSDPT 1 2 ASESIISVPTIMEDDDQEVDSADESVSNEMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTQGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNK IVQILKVLPTSSACCEKGRNALQRVRKNNRSrlTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSVDHGSEFYPDi* 0 >PRDM11_anaPla Anas platyrhynchos (duck) blast/HQ902403 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MSENLKDCLNQTQASLGEMVTIKTEACSPHRDQEYGQPc 2 1 SGRPDPQSMDVEPKKLKGKRDLIVTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGMEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YVIISREEREQNLMAFQHSERIYFRACRDIRPGEKLRVWYSEDYMKRLHSMSQETINRNLTR 1 2 GDKRLQREKSEKNVENQEDMRGPLQLTTLKQGKSPYKRSCDEGESHPQTKKKKIDLIFKDVLEASLESAKFEENQLATSTPLSIRTASKYQAEDIFERCGTAMQHGSLNLSRNRSEEEWKIPHGSSFSSAKEVGILDDDEEEPLSLKADSPTELSLASAQGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEPPELPPQVPELQEFSDPT 1 2 ASESIISVPTIMEDDDQEVDSADESVSNDMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTRGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNK IVQILKVLPTSSACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSMDHGSEFYPDI* 0 >PRDM11_taeGut Taeniopygia guttata (finch) XM_002199814 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MSENLRDCLIQTQASLREMVTIKTEACSPHRDQEYGQPC 2 1 SGRPDPQSMEMEPKKLKGKRDVIMTKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGMEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDRSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YVIISREEREQNLMAFQHSERIYFRACRDIHPGEKLRVWYSEDYMKRLHSMSQETMNRSFTS 1 2 GDKMLQNENSEKNVENQEDARGALQFTTLKQGKSPYKRSCDEGESHPQTKKKKIDLIFKDVLEASLESAKFEENQLATSTPLSLRRASKYQAEDIFEQCGNAMQRSSLSLSRNQSESEWRVPHSSSFISAKEMSILEDEEEEPLSLKADSPTELSLASAQGNSHEIPSTSFCPNCIRLKKKIRELQAELDMLRSGKLPEAPVLPPQVPELQEFSDPT 1 2 ASESIISVPTIMEDDDQEVDSADESVSNDMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAE AKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTRGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNK IVQILKVLPTSSACCEKGRSALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSMDHGSEFYPDI* 0 >PRDM11_anoCar Anolis carolinensis (lizard) blat/XM_003214639 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 0 MSEKLNDCLGEMVTIKTEPCSPCREEEYGQLW 2 1 SSRKVDSQSVDVEPKKLKGKQDLIMSKSFQQVDFW 1 2 FCESCQEYFVDECPNHGPPMFLSDAPVPIGIPDRAALTVPPGMEVVKEANGERDVRCVGEIIPKGRIYGPYEGKLSSQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETTSNWMR 2 1 YVAISREEREQNLMAFQHSERIYFRTCRDIRPGERLRVWYSEDYMKRLHSMSQETINRNLTR 1 2 GDKKSLRERSERNTENQMEMLYPLELTISKQGKSPYKRCSEEGVSQPQAKKKKIDLIFKDVLEASLESTKMEEHKVTRNSAPSTRKSSRFREQDASESCGTGMQHNSPTHSGSRN EDEWKVPHGPSFSVSKETGLLEDEGEEPLSFKLNSPTDLTLAPIDDEALGLPTTSLCPNCIRLKKKIRELQAELNMLRSGKLVEPPLLPPQVPEYQAFSYPT 1 2 ASETIMSVPTIMEDDDQEVDSADESVSNDMITATDEPSKMSAVTRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYRLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYCDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERVRQSPFLSIILDGQSDDLLADTVAVYVQYISSDGPPATEFLSLQELGFSATDSYIQALDRAF SSLGIRLQDERPSVGLGIDGANITASLRANMYMTIRKTLPWLLCLPLMIHKPHLEVLDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAFIFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGVAVKNLRVAE AKFQSIREKICQKTQVILAQRFEPRTRAFVKACQVFDLAMWPRSAEELMSYGREDMVQIFDHLEAVPTFSTDIIREGMDTRGSLLMEWRELKVDYYTKNGFKDLISHICKYRQRFPLLNK IIQILKVLPTSTACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFEAKRALDSWFEEKSSNSYALSAEMLSRMSSLDHKPMLQSMDHGSEFYPDI* 0 >PRDM11_xenTro Xenopus tropicalis (frog) blat/CF781198 3RAY coverage PhosS knuckle SET ZnF_TTF hATC_dimerization 1 MSEISKECRVAFSPSLGDIVRVKREVGSPVEEQGYGHFR 2 1 SSVGPNSRCLDMEPKRLKEKRESTMSKSLQQVDFW 1 2 FCESCQEYFVDECPSHGPPILVPDTLVPIGMPERAALSVPCGIEVVKDSSGESEVRCVNEVIPKGHMFGPYEGQICSQDKSSGFFSWL 0 0 IVDNNNRYKSIDGTDEAYANWMR 2 1 YVVISREEREQNLMAFQHSEKIYFRTCRDIQPGEKLRVWYSEDYMKRLHSMSQETINRNLTQ 1 2 GDKRLLRENNERLLENQEDVKGTFPLATLKQGKSLYKRSCEEVDLHPQTKKKKIDLIFKDVLEASLETARIDEYHLVTSSPLSGQKKNPKYLYENHGDRCRMNRQCSSPQNQIRNMRDWKAKHVSASGLNRQASFPEDEVEDHSSVKAESPTESSAIGNVDEIPTTSFCPNCIRLKKKIRELQAELEMLRSEKMAETSQMTNQINEIPEFADAS 1 2 APEGVAIATTMIDDDEQEVDSADESVSNDMMAATDEPSKMSAGSGRRIRRFKQEWLKKFWFLRYSSTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYYDFRPLAELLRKCELRVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSEDLLADTVAVYVQYTSSDGPPATEFLSLQELGLPTTESYLQGIDRAF SALGIRLQDERPTVGLGVDGANITAGLRANLYMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTAATLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADTSAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDEKVEEAIQEISRLTDSPGEYLQEFEENFRESFNGIALKNLRVAE AKFQSIREKICQKTQVTLAQRFDSRSRMFVKACQVFDLSTWPRTTEELINYGEEDMLQIYELLETIPNFLHDLGREVADTRGNLLMEWRELKADYCTKNGFKDLIGHICKYKQRFLFLNK IVQILKVLPTSTACCEKGRNALQRLRKNNRSRLTLDQMSDLLAIAVNGAPIANFDAKRALDSWFEEKSGNSYSLSAEMLSKMSSLDQKPLLQPMEHGSEYYQDI* 0 >PRDM11_latCha Latimeria chalumnae (coelocanth) AFYH01005054 3RAY coverage knuckle SET ZnF_TTF hATC_dimerization 1 2 1 STGAAETPRIEGEPKRTKGKLETIMAKTLQQVDFW 1 2 FCEECQEHFVVECPTHGPPVFTMDTPVPVGMPERAALTAPPGIHIVKGSNGEIDVECVDEVVQKGRIFGPYEGQITTQDKSAGFFSWL 0 0 IVDKNNRYKSIDGTDETKANWMR 2 1 YVVISRDEREQNLLAFQHSEKIYFRASRNLHPGERLRVWYSDEYMKRLHSMSQETIDRNLTA 1 2 GNLKLQRENSEEGWDAQENLRGMLLKQGKSSYKRGNDEAESHQQPKRKKIDLIFKDVLEASLESSKLEGNSLATSSPLPLKKPIKFQLEDVLQKPEYYYKHVSQLLGRGEVEWKSHQKSGCSLPDNEDSDRIKEESPDEVPGNSTEEDPEDVPTTSFCPNCIRLKKKIRELQEELDRLRSGQPPASPQLPQVQELLEPPG 2 VQEAHPSVSLMEDDDQEVDSADESVSNDMIAASDETSKITVGASRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTVLFNTAYHLALEGRPYLDFRPLSDLLRKCELKVVDQYMNEGDCQILIHHIARALQEDLIERIRQSPFLSVILDGQTDDILADTVAVYIQYTTSDGPPATEFLSLQELGCVTTDSYVQAVDRAF AVFGLRLQDQRNVVGLGVDGTCLTAGLRANLFMTIRKTLPWLLCLPFMVHKPHLEVLDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKWIIGEQN VLNALIKDYLEVVAHLKDVSGQTQRADAAAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAFVFQGEYLLVCQVDDKIEEAIQEISRLSDSPGEYLMEFEENFRESFNGIALKNLRVAE AKFQSIREKICQKTQVILAQRFDNRSRPFIKACQMLDIATWPRSTDDLKNFGEEEIMVIYEQLELVPTFAREVCREGTDNRGSLVMEWRELKADFYSKNGFKDLIGHICKYRQRFPILNR VLQILKVLPSSAACCEKGRSALQRIRKNNRSRLTLDQLNDLLTIAINGPSIANFDAKRALDSWFEEKSGNSYALSAEVLNRMSADQKPMLQGMDFVSDFYPDI* 0 >PRDM11_danRef Danio rerio (zebrafish) blat/EB776339/EB946706/BX088562/XM_688756 3RAY coverage knuckle SET ZnF_TTF hATC_dimerization 0 MADSSTNPDHSSMEAEGECSTS 2 1 ASNEKSAEEPNKRLKVEHERYSSFW 1 2 FCEECKKYYLEDCPTHGPPVFVPDTPVVSGVPNRAALTAPSGIEVRRNGDKVDVYCMDEKIPKGALFGPYKGQIMASDKPSGPYSWM 0 0 IVDKDSKYKFIDGSDEATANWMR 2 1 FIHITSDESEQNLSAFQHGDQIYFRVCHRLKVGEKLGVWYSSEYMKRLQSVSRDSIDHNLDT 1 2 GVKSEDQEEPKGPVLRSAMHGRRTLSKHGSDEAENQPQAKKKKIDLIFKDVLEASLEANQSQNNPLNSTLSFPRARTNVCQVFCHPDAESKESVFTSGLVSMDHHEIGFDGKCIKMENTEEDEALTSEGPSTSFCPNCVRLKRRIRELEAELHRLRGQGHAEVKPVPASEMLAGEDHR 1 2 DTMTPIPAALEEDDQDVDSADESISADLLVAADESSKLSVGSGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMMTLLNAAYHLALEGRPFSDLRPLAELLKKCDLKVVDQYMNENDCQILIQHISRAFKEDLAEKIRLSPFLSIIMDGQNDDLLADMVAVYVQFTTTDGLPATEFLSLQRLCGGNVEGYLQAVDRAF GVLGLRLQDMLVVGLGIDGSNISSSLRANLYVAIRKTIPWVLCLPVMIHRPHLEVLDAISGKELSCLEDLENNLKQLLSFYRYSPRLMAELRSSAPTLSEETEFLGDIRAVRWIIGEPN VLNALIKDYLEVVAHLKTISNQTQRGDAAAIALSLLQFLLDYQSVKLIYFLLDVIAVFSRLAFIFQGDYLLVSQVDAKIEDAIHEIGQLVDSPGEYLQEFEDNFRESFNGVDLKNLRVAE SKFQSIREKICQQSQCILAQRFEPRSRTVVQACQVLDLASWPINRDDLGAYGEEEILVIFDHLETIPSSGRERSIERTDARGSLVVEWRDLKADYCSVNGFKEVVSHIFRYKQRYPLLN HILQIVRVLPTSTTCCDKGRGSLQKVRRNSRSRLTLDQINDLLTLAVNGPPIGSFDGKRALDSWFEEKSGNSISLSTEVLSRMSTTEQKSVLHNMDMNAEYYPDV* 0 >PRDM11_oreNil Oreochromis niloticus (tilapia) XM_003458287 first exons uncertain 0 MASENCRQIASCLQIEAEKAWRRSEPGRALC 1 2 fCEECQDCFHKECPSHGPPLFIQDTHAAPGTANRAALTVPSGLEVFSEEDEVDVRCVDAIYPKGALFGPYEGELVSKDRSSGFFSWI 0 0 IVDVNNTYQSIDGSDETKANWMR 2 1 YVRTSSEESDRNLTAFQHGKNIYFRVCRALVAGEKLRVWYSDDYIRRLHCVSQESIDRNLDT 1 2 GPGKDFKSRCLQSALQGKLSKQLSEESDGQPPAKRKKIDLIFKDVLEASLEESGKFRSRSGQPSEYKVPALVSRFDSSETGFGIPNLKVEEKEEEENQNTEKPSTSFCPNCVKLKRRILELEEELSRLRGEQRDAAASATSEQTQPQRDQAPPHPEQGPIEDFQ 1 2 GMEPLTPTQVVLDEDDQDVDSADESIAADLVISPEDSSKLSSGGGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CKNMMLLFNAAYHLALEGRPFSDLRSLAELLKKCELKVVDQYMNEGDCQILIHHIARAVKEDLAEKMRLSPFLSVIMDAQNDDLFSDMVAVYVQFVTNEGSPNTEFLSLQRLTVANVDGYLQVMDRAF GVLGLRFQDLLVVGLGVDGTNISSGMRANLYIAVQKTFPWILCLPIMIHRPHLEVLDAISGKELSCLEDLENNLKQLLSFYRYSPRMMAELRSTAPTLSEETEFLGDIRAIRWIIGEPN VLNALIKDYLEVVAHLKEISSQTQRADAAAIALTLLQFLMDYQSVKLIYFLLDIIAILSRLAFTFQGEYLLVSQVEAKIEEAIQEIGQLVDCPGEYLQEFEENFRESFNGVALKNLRVAE SKFQSIREKICNRSQSILSQRLDLQSRSFAKACKVLDLSTWPSNHEDLQAYGDEEIKIIFNHLESIPTAAQEGSQTEARGSLVVEWKDLKADYYSMNGFKEVIGHICRYKQRFPLLN RIVQVIRVLPSSTACCDKGRGSLQKMCKNNRSRLTLEQMNDLLTVAINGPPIANFDGKRALDSWFEEKSGSSYSLSAEVLNRMSAADQKCVLHSVDVNAEFYPDV* 0
PRDM11 fragmentary sequences from the unrecognized terminal exon were utilized in a Dec 2011 study to determine the topology of the amniote tree, notably to resolve the taxonomic position of turtles (outgroup to crocodillians + birds). Because that study sequenced some rarely studied species such as skink, salamander, caecilian and amphibia, the sequences are reproduced here and supplemented with the appropriate region of the full length sequences PRDM11 above (which were largely not used in the study). The fragment begins within the ZNF_TTF zinc finger and terminates well before the end of the exon.
>PRDM11_homSap Homo sapiens (human) revised 511+722 aa WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSVILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAF SALGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTAATLCEETEFLGDIRAVRW >PRDM11_musMus Mus musculus (mouse) blat WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAF AALGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRW >PRDM11_canFam Canis familiaris (dog) blat WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAF SALGIRLQDEKPTVGLGIDGANVTASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRW >PRDM11_loxAfr Loxodonta africana (elephant) blat WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSGTESYLQALDRAF STLGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVKW >PRDM11_monDom Monodelphis domestica (opossum) blat WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDILADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTASTLCEETEFLGDIRAVR >PRDM11_ornAna Ornithorhynchus anatinus (platypus) blat WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF AALGVRLQDEKPTVGLGVDGANVTASLRAGMFMTVRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTAATLCEETEFLGDIRAVRW >PRDM11_galGal Gallus gallus XM_421099 WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKW >PRDM11_melGal Meleagris gallopavo (turkey) blat/XM_003206406 WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKW >PRDM11_anaPla Anas platyrhynchos (duck) blast/HQ902403 WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_taeGut Taeniopygia guttata (finch) XM_002199814 WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_strCam Struthio camelus (ostrich) HQ902400 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_allMis Alligator mississippiensis (alligator) scaffold:58581 WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAF SSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPKLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_allSin Alligator sinensis (alligator) HQ902411 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAFSSLGIRLQDEKPT IGLGVDGANITASLRADLFMTIRKALPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPKLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_croSia Crocodylus siamensis (crocodile) HQ902406 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAFSSLGIRLQDEKP TIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPKLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_carIns Carettochelys insculpta (turtle) HQ902407 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFCTTDSYLQALDRAFSSLGIRLQDEKPT IGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_podUni Podocnemis unifilis (turtle) HQ902402 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFCTTDSYLQALDRAFSSLGIRLQDEKPT IGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_traScr Trachemys scripta (turtle) HQ902399 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFCTTDSYLQALDRAFSSLGIRLQDEKP TIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_pelSin Pelodiscus sinensis (turtle) HQ902412 frag ZnF_TTF WFLQYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARSLREDLVERIRQSPFLSIILDGQSDDWLADTVAVYVQYTSSDGPPATEFLSLQELGFCTTDSYLQALDRAFSSLGIRLQDEKPT IGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_anoCar Anolis carolinensis (lizard) blat/XM_003214639 WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYRLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYCDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERVRQSPFLSIILDGQSDDLLADTVAVYVQYISSDGPPATEFLSLQELGFSATDSYIQALDRAF SSLGIRLQDERPSVGLGIDGANITASLRANMYMTIRKTLPWLLCLPLMIHKPHLEVLDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_hemBow Hemidactylus bowringii (gecko) HQ902409 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYRLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYCDFRSLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYISSDGPPATEFLSLQELGFSTADSYIQALDRAFSSLGIRLQDEKPS VGLGMDGANITASLRANMYMTIRKTLPWLLCLPLMVHKPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_sciRee Scincella reevesii (skink) HQ902404 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYRLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYCEFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERVRQSPFLSIILDGQSDDLLADTVAVYVQYISSDGPPATEFLSLQELGFSTTDSYIQALDRAFSSLGIRLQDEKPS VGLGIDGANITASLRANMYMTIRKTLPWLLCLPLMVHKPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_dibBou Dibamus bourreti (skink) HQ902405 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYRLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYCDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDLLADTVAVYVQYISSDGPPATEFLSLQELGFSATDSYIQALDRAFSSLGIRLQDEKPT VGLGVDGANITASLRASMYMTIRKTLPWLLCLPLMVHKPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAVKW >PRDM11_najAtr Naja atra (cobra) HQ902408 frag ZnF_TTF WFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYRLRMHPEKTEEM CRNMTLLFNTAYHLAIEGRPYCDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLIERVRQSPFLSIILDGQSDDLLADTVAVYVQYVSCDGPPATEFLSLQELGFSTTDSYVQALDRAFSSLGMRLQDEKPS VGLGIDGANITASLRANIYMTIRKTLPWLLCLPLMVHKPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRAIKW >PRDM11_batYen Batrachuperus yenyuanensis (salamander) HQ902410 frag ZnF_TTF WFLRYSSTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRSMTLLLNTAYHLAVEGRPYYDFRPLAELLRKCELRVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSEYLLADTVAVYVQYTSNDGPPATEFLSLQELGVPTTESYLQAIDRAFSALGIRLQDEKPT VGLGVDGFNITAGLRANMYMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTAATLCEETEFLGDIRGVRW >PRDM11_ichBan Ichthyophis bannanicus (caecilian amphibian) HQ902398 frag ZnF_TTF WFLRYSSTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLALEGRPYFDFRPLAELLRKCELRVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSEDLIADTVAVYVQYTSCDGPPATEFLSLQEIGLSTAESYLQGIDRAFSALGIRLQDEKPT VGLGIDGANITAGLRANMYMTIRKTLPWLLCLPFMVYRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRTTASTLCEETEFLGDIRAVRW >PRDM11_xenTro Xenopus tropicalis (frog) blat/CF781198 WFLRYSSTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYYDFRPLAELLRKCELRVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSEDLLADTVAVYVQYTSSDGPPATEFLSLQELGLPTTESYLQGIDRAF SALGIRLQDERPTVGLGVDGANITAGLRANLYMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTAATLCEETEFLGDIRAVKW >PRDM11_ranNig Rana nigromaculata (dark-spotted frog) HQ902401 frag ZnF_TTF WFLRYSSTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEM CRNMTLLFNTAYHLAMEGRPYYDFRPLAELLRKCELRVVDQYMNEGDCQILIHHIARALREDLIERIRQSPFLSIILDGQSEDLLADTVAVYVQYTSNDGPPATEFLSLQELALPTTESYLQGIDRAFSALGIRLQDERPS VGLGIDGVNITAGLRANLYMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRLTAATLCEETEFLGDIRAVKW
