User:Ping Yuan

Academic qualification 1995 B.S. Central China Normal University, PRC 1998 M.S. Wuhan Institute of Virology, Chinese Academy of Science, PRC 2004 Ph.D. National University of Singapore, Singapore Previous academic position 2006-2010 Postdoctoral fellow, Genome Institute of Singapore, Singapore 2004-2006 Research associate, Princeton University, USA 2001-2004 Junior research fellow, Institute of Molecular and Cell Biology, Singapore 2001, Visiting research fellow, Harvard Medical School, USA 1998-2001, Junior research fellow, Institute of Agrobiology, Singapore Present academic position held Aug.30, 2010-present Assistant professor of Chemical Pathology, The Chinese University of Hong Kong Previous relevant research work • Use genome-wide ChIP-seq technique to map the transcription factor network in mouse embryonic stem cells • Study early embryo development and pluripotent stem cells • Generate induced pluripotent stem cells from fibroblast and study the mechanism. Publication records Within five years 1. Xu, H., Tsang, K.Z., Chan, C.N., Yuan, P., et.al. The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells. Cell Transplantation (2011), Accepted. 2. Han, J., Yuan, P., Yang, H., et.al. Tbx3 improves the germ-line competency of induced pluripotent stem cells Nature (2010) , 463, 1096-1100 3. Yuan, P.*, Han, J.*, Guo, G., et.al. Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes & Development (2009), 23, 2507-2520 (* represents equal first author) 4. Chen, X.*, Han, X.*, Yuan, P., et.al. Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells (* represents equal first author) Cell, (2008), 133, 1106-1117 Beyond recent five years 1. Yuan, P.*, Saxena, S.*, Dhar, S.K.*, et.al. A dimerized coiled coil domain and an adjoining part of Geminin interact with two sites on Cdt1 for replication inhibition. Molecular Cell, (2004), 15(2), 245-258 (* represents equal first author) 2. Yuan, P., Jedd, G., Kumaran, D., Swaminathan, S., et.al. A HEX-1 crystal lattice required for Woronin body function in Neurosporal Crassa Nature Structural Biology, (2003), 10(4), 264 -270