Immunogenomics papers: Difference between revisions

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(Created page with "* [http://stm.sciencemag.org/content/1/12/12ra23 Boyd et al, Fire lab] ** sequenced IGH-locus with BIOMED2 primers")
 
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* [http://stm.sciencemag.org/content/1/12/12ra23 Boyd et al, Fire lab]
* [http://www.jimmunol.org/content/184/12/6986.long Boyd 2010 J of Immunol, Collins lab, Stanford]
** sequenced IGH with BIOMED2 primers of 12 people
** describe variation
* [http://stm.sciencemag.org/content/1/12/12ra23 Boyd et al, Fire lab, Stanford]
** sequenced IGH-locus with BIOMED2 primers
** sequenced IGH-locus with BIOMED2 primers
* [http://bioinformatics.oxfordjournals.org/content/26/24/3129.full, Bioinformatics 2011, Collins lab, Stanford]
** Benchmark of IGH-identifiers
* [http://www.ncbi.nlm.nih.gov/pubmed/8601832 Tomlinson 1996]
** Sanger sequencing of <1000 IGH sequences
** compare germline mutations (=IMGT) versus somatic mutations
** In parts of antibody where there is little germline variation, there is lots of somatic mutations, and the inverse
* [http://www.pnas.org/content/106/48/20216 Glanville 2009, Pons lab, Pfizer]
* [http://www.ncbi.nlm.nih.gov/pubmed/14636599 Zemlin 2003]
** CDR3 composition is very different between human and mouse
== Reviews ==
* [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038007/ Fisher 2010]

Latest revision as of 01:32, 23 August 2011

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