Selenoprotein evolution: SECIS: Difference between revisions

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=== SEPP1a: 20 SECIS insertion sequences ===
=== SEPP1a: 20 SECIS insertion sequences ===
<pre>
<pre>
>SEPP1a_homSap Homo sapiens (human) COVE score: 30.80
>SEPP1a_homSap Homo sapiens (human) score: 30.80
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aauuagc aguuuag aauggaggaa
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aauuagc aguuuag aauggaggaa


>SEPP1a_panTro Pan troglodytes (chimp) COVE score: 30.80
>SEPP1a_panTro Pan troglodytes (chimp) score: 30.80
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagc aguuuag aauggaggaa
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagc aguuuag aauggaggaa


>SEPP1a_macMul Macaca mulatta (rhesus) COVE score: 30.80
>SEPP1a_macMul Macaca mulatta (rhesus) score: 30.80
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagc aauuuag aauggaggaa
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagc aauuuag aauggaggaa


>SEPP1a_tupBel Tupaia belangeri (tree_shrew) COVE score: 31.04
>SEPP1a_tupBel Tupaia belangeri (tree_shrew) score: 31.04
uuuucuuuuu ccaguau ucuauuugcauua augaa gacagaaacau aa acuaugaccuag ggguuucgguu ggau agguagc aauuuag aauggaggaa
uuuucuuuuu ccaguau ucuauuugcauua augaa gacagaaacau aa acuaugaccuag ggguuucgguu ggau agguagc aauuuag aauggaggaa


>SEPP1a_musMus Mus musculus (mouse) COVE score: 32.57
>SEPP1a_musMus Mus musculus (mouse) score: 32.57
uuuccuuuuu ccagugu ucuaguuacauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau agcuugu aauuaag aacggagaaa
uuuccuuuuu ccagugu ucuaguuacauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau agcuugu aauuaag aacggagaaa


>SEPP1a_ratNor Rattus norvegicus (rat) COVE score: 32.57
>SEPP1a_ratNor Rattus norvegicus (rat) score: 32.57
uuuucuuucu ccagugu ucuaguuacauug augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau agcucgu aauuaag aacggagaaa
uuuucuuucu ccagugu ucuaguuacauug augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau agcucgu aauuaag aacggagaaa


>SEPP1a_cavPor Cavia porcellus (guinea_pig) COVE score: 34.57
>SEPP1a_cavPor Cavia porcellus (guinea_pig) score: 34.57
uguucuuuuu ccagaau ucuauuugcauug augaa aacagaaacau aa acuaugaccuag ggguuucuguu ggau acauagu aauuuag aauggaggaa
uguucuuuuu ccagaau ucuauuugcauug augaa aacagaaacau aa acuaugaccuag ggguuucuguu ggau acauagu aauuuag aauggaggaa


>SEPP1a_oryCun Oryctolagus cuniculus (rabbit) COVE score: 33.28
>SEPP1a_oryCun Oryctolagus cuniculus (rabbit) score: 33.28
uuuucuuuuu ccagcau ucuacuugcauua augau aacagaaacgu aa acuaugaccuag ggguuucuguu ggau aauuagua auuuag aauggagaag
uuuucuuuuu ccagcau ucuacuugcauua augau aacagaaacgu aa acuaugaccuag ggguuucuguu ggau aauuagua auuuag aauggagaag


>SEPP1a_sorAra Sorex araneus (shrew) COVE score: 33.08
>SEPP1a_sorAra Sorex araneus (shrew) score: 33.08
uuuucuucuu ccaauau ucuauuugcauua augaa gacagaagcaa aa acuaugaccuag gggcuucuguu ggau acuua gcaauugg gauggagaaa
uuuucuucuu ccaauau ucuauuugcauua augaa gacagaagcaa aa acuaugaccuag gggcuucuguu ggau acuua gcaauugg gauggagaaa


>SEPP1a_eriEur Erinaceus europaeus (hedgehog) COVE score: 33.29
>SEPP1a_eriEur Erinaceus europaeus (hedgehog) score: 33.29
uuuucuuuuu ccagcau ucuacuugcagua augag gacagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa
uuuucuuuuu ccagcau ucuacuugcagua augag gacagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa


>SEPP1a_canFam Canis familiaris (dog) COVE score: 33.38
>SEPP1a_canFam Canis familiaris (dog) score: 33.38
uuuucuuuuu ccagcau ucuacuugcauua augaa aacagagacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa
uuuucuuuuu ccagcau ucuacuugcauua augaa aacagagacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa


>SEPP1a_equCab Equus caballus (horse) COVE score: 29.34
>SEPP1a_equCab Equus caballus (horse) score: 29.34
uuuucuuuuu ccagcau ucuacuugcauua augag aacagaaacgu aa acuaugaccuag ggguuucugug ggau aguuagca auuuag aauggaggaa
uuuucuuuuu ccagcau ucuacuugcauua augag aacagaaacgu aa acuaugaccuag ggguuucugug ggau aguuagca auuuag aauggaggaa


>SEPP1a_bosTau Bos taurus (cow) COVE score: 30.75
>SEPP1a_bosTau Bos taurus (cow) score: 30.75
uuuucuuuuu ccaguau ucuacuugcguua augag aacagaaacgu aa acuauaaccuag ggguuucuguu ggau gguuggc aacuaag aauggaggaa
uuuucuuuuu ccaguau ucuacuugcguua augag aacagaaacgu aa acuauaaccuag ggguuucuguu ggau gguuggc aacuaag aauggaggaa


>SEPP1a_dasNov Dasypus novemcinctus (armadillo) COVE score: 32.57
>SEPP1a_dasNov Dasypus novemcinctus (armadillo) score: 32.57
ucuucuuuuu ccagcau ucuauuugcauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggagaaa
ucuucuuuuu ccagcau ucuauuugcauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggagaaa


>SEPP1a_loxAfr Loxodonta africana (elephant) COVE score: 32.57
>SEPP1a_loxAfr Loxodonta africana (elephant) score: 32.57
ucuucuuuuu ccagcau ucucuuugcauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa
ucuucuuuuu ccagcau ucucuuugcauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa


>SEPP1a_echTel Echinops telfairi (tenrec) COVE score: 32.80
>SEPP1a_echTel Echinops telfairi (tenrec) score: 32.80
ucuucuuuuu ccagcau ucuuuuugcauua augag aacagaaacgu aa acuaugaccuag ggguuucuguu ggau acucugca auuuag aauggaggaa
ucuucuuuuu ccagcau ucuuuuugcauua augag aacagaaacgu aa acuaugaccuag ggguuucuguu ggau acucugca auuuag aauggaggaa


>SEPP1a_monDom Monodelphis domestica (opossum) COVE score: 30.77
>SEPP1a_monDom Monodelphis domestica (opossum) score: 30.77
uguuucucuu ccugugu ucugcuugcauua augaa gacagaagcau aa acuauaacuuag gggcuucuguu ggau aauuugca auccag aauggaggaa
uguuucucuu ccugugu ucugcuugcauua augaa gacagaagcau aa acuauaacuuag gggcuucuguu ggau aauuugca auccag aauggaggaa


>SEPP1a_ornAna Ornithorhynchus anatinus (platypus) COVE score: 29.28
>SEPP1a_ornAna Ornithorhynchus anatinus (platypus) score: 29.28
ugccuccugc cguucug cuugcauuu augag aacagaaacau aa acuauaaaccuag ggguuucuguu ggau agu uagcaau caagaauggg
ugccuccugc cguucug cuugcauuu augag aacagaaacau aa acuauaaaccuag ggguuucuguu ggau agu uagcaau caagaauggg


>SEPP1a_anoCar Anolis carolinensis (lizard) COVE score: 32.99
>SEPP1a_anoCar Anolis carolinensis (lizard) score: 32.99
cacuucuacc auucugu uugcauuc augaa aacagaagccg aa acuaugaccuag gggcuuuuguu ugau auauu gcagcca agaacaggag
cacuucuacc auucugu uugcauuc augaa aacagaagccg aa acuaugaccuag gggcuuuuguu ugau auauu gcagcca agaacaggag


>SEPP1a_danRer Danio rerio (zebrafish) COVE score: 32.87
>SEPP1a_danRer Danio rerio (zebrafish) score: 32.87
uuucaccucu aagugcu uuauguggucuuu augaa ggcaggugcag aa acuaugcacuag uggugucuguc ugau guuu ggccau acagagcaga
uuucaccucu aagugcu uuauguggucuuu augaa ggcaggugcag aa acuaugcacuag uggugucuguc ugau guuu ggccau acagagcaga
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</pre>
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=== SEPP1b: 16 SECIS insertion sequences ===
=== SEPP1b: 16 SECIS insertion sequences ===
<pre>
<pre>
>SEPP1b_homSap Homo sapiens (human) COVE score 20.32
>SEPP1b_homSap Homo sapiens (human) score 20.32
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuau gguuaauacu
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuau gguuaauacu


>SEPP1b_panTro Pan troglodytes (chimp) COVE score 20.32
>SEPP1b_panTro Pan troglodytes (chimp) score 20.32
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuau gguuaauacu
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuau gguuaauacu


>SEPP1b_macMul Macaca mulatta (rhesus) COVE score 20.32
>SEPP1b_macMul Macaca mulatta (rhesus) score 20.32
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuac gguuaauacu
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuac gguuaauacu


>SEPP1b_tupBel Tupaia belangeri (tree_shrew) COVE score 16.22
>SEPP1b_tupBel Tupaia belangeri (tree_shrew) score 16.22
uggacugcuu agaaagu auuuccauaguca augau gguucaauaggc aa acuaau cccuauaaacc ugaa cuc cuuuau gguuaauacu
uggacugcuu agaaagu auuuccauaguca augau gguucaauaggc aa acuaau cccuauaaacc ugaa cuc cuuuau gguuaauacu


>SEPP1b_oryCun Oryctolagus cuniculus (rabbit) COVE score 15.69
>SEPP1b_oryCun Oryctolagus cuniculus (rabbit) score 15.69
cuuuaggcug cucagag uaucuccauauua augau gguuuaacaggu aa acuaaa cccuaugaacc ugaa uuu cuuuaug gauaauacua
cuuuaggcug cucagag uaucuccauauua augau gguuuaacaggu aa acuaaa cccuaugaacc ugaa uuu cuuuaug gauaauacua


>SEPP1b_sorAra Sorex araneus (shrew) COVE score 15.19
>SEPP1b_sorAra Sorex araneus (shrew) score 15.19
uugguugcuu agaaagu auuuccauaguca augau gguuuaauaggu aa acuuauuu ccuguaaaccc ugaa cuu cuuuau gguuaauacc
uugguugcuu agaaagu auuuccauaguca augau gguuuaauaggu aa acuuauuu ccuguaaaccc ugaa cuu cuuuau gguuaauacc


>SEPP1b_canFam Canis familiaris (dog) COVE score 16.12
>SEPP1b_canFam Canis familiaris (dog) score 16.12
ugauugcuua gaaagua uuuccauaguca augau gguucaauaggu aa acuaag uccuauaaacc ugaa cuccua uaugguu aauacuauua
ugauugcuua gaaagua uuuccauaguca augau gguucaauaggu aa acuaag uccuauaaacc ugaa cuccua uaugguu aauacuauua


>SEPP1b_equCab Equus caballus (horse) COVE score 16.12
>SEPP1b_equCab Equus caballus (horse) score 16.12
uugauugcuu agaaagu auuuccauaguca augau gguucaauaggu aa acuaag uccuauaaacc ugaa cuc cuuuau gguuaauacu
uugauugcuu agaaagu auuuccauaguca augau gguucaauaggu aa acuaag uccuauaaacc ugaa cuc cuuuau gguuaauacu


>SEPP1b_bosTau Bos taurus (cow) COVE score 13.38
>SEPP1b_bosTau Bos taurus (cow) score 13.38
uugauugcuu agaaagu auuuccauaguca augau gguucaauaggc aa accagg uccuauaaacc ugaa uuu uuuuuau ggucaauacu
uugauugcuu agaaagu auuuccauaguca augau gguucaauaggc aa accagg uccuauaaacc ugaa uuu uuuuuau ggucaauacu


>SEPP1b_dasNov Dasypus novemcinctus (armadillo) COVE score 14.48
>SEPP1b_dasNov Dasypus novemcinctus (armadillo) score 14.48
uaggcugcuu agaaagu auuuccauaauca augau gguucaguaggu aa acuaag cccuauaaacc ugaa cuc cuuuau gguuaauacc
uaggcugcuu agaaagu auuuccauaauca augau gguucaguaggu aa acuaag cccuauaaacc ugaa cuc cuuuau gguuaauacc


>SEPP1b_loxAfr Loxodonta africana (elephant) COVE score 14.36
>SEPP1b_loxAfr Loxodonta africana (elephant) score 14.36
cuaggcugcu uagaagu auuuccaucauca augau gguucaauaggu aa accaaa uccuauaaacc ugaa cuc cuuaug guuaauacug
cuaggcugcu uagaagu auuuccaucauca augau gguucaauaggu aa accaaa uccuauaaacc ugaa cuc cuuaug guuaauacug


>SEPP1b_echTel Echinops telfairi (tenrec) COVE score 17.68
>SEPP1b_echTel Echinops telfairi (tenrec) score 17.68
uaggcugcuu agaaagu auuuccauaguua augau gauucauuaggu aa auuua gucuugugaauc ugaa cuc auuuau gguuaauacu
uaggcugcuu agaaagu auuuccauaguua augau gauucauuaggu aa auuua gucuugugaauc ugaa cuc auuuau gguuaauacu


>SEPP1b_monDom Monodelphis domestica (opossum) COVE score 16.17
>SEPP1b_monDom Monodelphis domestica (opossum) score 16.17
cagguugcuu agaaagu guucccauaguua augau gguuuaacaggu aa auugac uccuguggacc ugaa cuc uuuuau gguucauacu
cagguugcuu agaaagu guucccauaguua augau gguuuaacaggu aa auugac uccuguggacc ugaa cuc uuuuau gguucauacu


>SEPP1b_ornAna Ornithorhynchus anatinus (platypus) COVE score 17.91
>SEPP1b_ornAna Ornithorhynchus anatinus (platypus) score 17.91
gaauggcuua gaaagua uuugccauaguua augac gguucaguaggg aa auccaa uccuaugaacc ugag cucuuc uaugguu aaugcuaaua
gaauggcuua gaaagua uuugccauaguua augac gguucaguaggg aa auccaa uccuaugaacc ugag cucuuc uaugguu aaugcuaaua


>SEPP1b_anoCar Anolis carolinensis (lizard) COVE score 16.09
>SEPP1b_anoCar Anolis carolinensis (lizard) score 16.09
ugcuuagauu gugcuug ccauaguuc augau gguuuauuaggg aa auaaa uucuacaaaacc ugaa uuccu uuauggu gaacacagaa
ugcuuagauu gugcuug ccauaguuc augau gguuuauuaggg aa auaaa uucuacaaaacc ugaa uuccu uuauggu gaacacagaa


>SEPP1b_danRer Danio rerio (zebrafish) COVE score 24.26
>SEPP1b_danRer Danio rerio (zebrafish) score 24.26
auagaugguu uuaaaca uuuuuuauacuua augaa gguuuucuggu aa aucuuguauc accuggaagac ccgag aaac uguaugg aaauguaugc
auagaugguu uuaaaca uuuuuuauacuua augaa gguuuucuggu aa aucuuguauc accuggaagac ccgag aaac uguaugg aaauguaugc
</pre>
</pre>
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=== SEPN: 14 SECIS insertion sequences ===
=== SEPN: 14 SECIS insertion sequences ===
<pre>
<pre>
>SEPN_homSap Homo sapiens (human) COVE score: 32.06
>SEPN_homSap Homo sapiens (human) score: 32.06
caguggcuuc cccggca gcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau guc uuugcag cugcaccuau
caguggcuuc cccggca gcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau guc uuugcag cugcaccuau


>SEPN_panTro Pan troglodytes (chimp) COVE score: 32.06
>SEPN_panTro Pan troglodytes (chimp) score: 32.06
gcaguggcuu cccuggc agcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau gucuuu gcagcug caccuauggg
gcaguggcuu cccuggc agcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau gucuuu gcagcug caccuauggg


>SEPN_macMul Macaca mulatta (rhesus) COVE score: 32.06
>SEPN_macMul Macaca mulatta (rhesus) score: 32.06
caguggcuuc cccagca gcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau guc uuugcag cugcaccuau
caguggcuuc cccagca gcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau guc uuugcag cugcaccuau


>SEPN_musMus Mus musculus (mouse) COVE score: 34.87
>SEPN_musMus Mus musculus (mouse) score: 34.87
guggcucccc cagcaac agccgc augau ggcugggucug aa aucgcaaa uggauccagcc ugau guccuc gcaguug cacauguggg
guggcucccc cagcaac agccgc augau ggcugggucug aa aucgcaaa uggauccagcc ugau guccuc gcaguug cacauguggg


>SEPN_ratNor Rattus norvegicus (rat) COVE score: 35.19
>SEPN_ratNor Rattus norvegicus (rat) score: 35.19
gguguuuccc ccagcag cagccgc augau ggcugggucug aa aucccaaa aggauccagcc ugau guccucg caguug cacauguggg
gguguuuccc ccagcag cagccgc augau ggcugggucug aa aucccaaa aggauccagcc ugau guccucg caguug cacauguggg


>SEPN_cavPor Cavia porcellus (guinea_pig) COVE score: 34.85
>SEPN_cavPor Cavia porcellus (guinea_pig) score: 34.85
gaauaaugau ccccgag cagcagcccc augau ggcuggauccg aa auccuaga uggaucuagcu ugau gcc uuugcag uugcacuuau
gaauaaugau ccccgag cagcagcccc augau ggcuggauccg aa auccuaga uggaucuagcu ugau gcc uuugcag uugcacuuau


>SEPN_sorAra Sorex araneus (shrew) COVE score: 33.75
>SEPN_sorAra Sorex araneus (shrew) score: 33.75
ggcuuuuccc cacccgc aaccgccuc augau ggcuggaucug aa auccuaga uggaucuggcu ugau gucuuu gcgauug uccuguggga
ggcuuuuccc cacccgc aaccgccuc augau ggcuggaucug aa auccuaga uggaucuggcu ugau gucuuu gcgauug uccuguggga


>SEPN_canFam Canis familiaris (dog) COVE score: 34.73
>SEPN_canFam Canis familiaris (dog) score: 34.73
ggcagugucu cccgcag cagcagcccc augau ggcuggaucug aa auccuaga uggguccagcu ugau guc uuugcag cugcaccuac
ggcagugucu cccgcag cagcagcccc augau ggcuggaucug aa auccuaga uggguccagcu ugau guc uuugcag cugcaccuac


>SEPN_felCat Felis catus (cat) COVE score: 28.82
>SEPN_felCat Felis catus (cat) score: 28.82
cggugucucc cccagca gcagcccc augau ggcuggaucug aa auccuaga cgggcccagcu ugau guc uuugcag cugcaccugu
cggugucucc cccagca gcagcccc augau ggcuggaucug aa auccuaga cgggcccagcu ugau guc uuugcag cugcaccugu


>SEPN_equCab Equus caballus (horse) COVE score: 37.53
>SEPN_equCab Equus caballus (horse) score: 37.53
ggagggacaa uggcucc ucgcggcugcccc augau ggcuggaucug aa auccugga uggguccagcu ugau gucuc cgcaguug caccuauggg
ggagggacaa uggcucc ucgcggcugcccc augau ggcuggaucug aa auccugga uggguccagcu ugau gucuc cgcaguug caccuauggg


>SEPN_bosTau Bos taurus (cow) COVE score: 31.65
>SEPN_bosTau Bos taurus (cow) score: 31.65
cgauggugcc cccuagc agccgcccc augau ggcuggaucug aa agcuuagg uggauccagcu ugau gucuuu gcaguug cuccuguggg
cgauggugcc cccuagc agccgcccc augau ggcuggaucug aa agcuuagg uggauccagcu ugau gucuuu gcaguug cuccuguggg


>SEPN_dasNov Dasypus novemcinctus (armadillo) COVE score: 26.61
>SEPN_dasNov Dasypus novemcinctus (armadillo) score: 26.61
gccgcuggcu ccuccag cagccgccgc augaa ggauggaucug aa aucccaga uggauccagcc cgau cuc uuugcag uugcaccugu
gccgcuggcu ccuccag cagccgccgc augaa ggauggaucug aa aucccaga uggauccagcc cgau cuc uuugcag uugcaccugu


>SEPN_loxAfr Loxodonta africana (elephant) COVE score: 31.75
>SEPN_loxAfr Loxodonta africana (elephant) score: 31.75
agugaugguu ccccaag caacugcccc augac agcugggucug aa auccuaga uggacccaguu ugau guc uuugcag uagcaccucu
agugaugguu ccccaag caacugcccc augac agcugggucug aa auccuaga uggacccaguu ugau guc uuugcag uagcaccucu


>SEPN_monDom Monodelphis domestica (opossum) COVE score: 26.99
>SEPN_monDom Monodelphis domestica (opossum) score: 26.99
gggacuucua uucuccu gcaacuguucuuu augau ggcuagauccu aa auccuaga ugggucaaguu ugau gucuug acaguaa cugaagggga
gggacuucua uucuccu gcaacuguucuuu augau ggcuagauccu aa auccuaga ugggucaaguu ugau gucuug acaguaa cugaagggga
</pre>
</pre>
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=== SEPHS2: 11 SECIS insertion sequences ===
=== SEPHS2: 11 SECIS insertion sequences ===
<pre>
<pre>
>SEPHS2_homSap Homo sapiens (human) COVE score: 20.81
>SEPHS2_homSap Homo sapiens (human) score: 20.81
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa accccauuaagg acugggagaggc agag caag ccucaga gcccaggccu
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa accccauuaagg acugggagaggc agag caag ccucaga gcccaggccu


>SEPHS2_panTro Pan troglodytes (chimp) COVE score: 20.81
>SEPHS2_panTro Pan troglodytes (chimp) score: 20.81
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa accccauuaagg acugggagaggc agag caag ccucaga gcccaggccu
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa accccauuaagg acugggagaggc agag caag ccucaga gcccaggccu


>SEPHS2_macMul Macaca mulatta (rhesus) COVE score: 20.90
>SEPHS2_macMul Macaca mulatta (rhesus) score: 20.90
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa acuccauuaagg acugggagaggc agag caag ccucaga gcccaggccu
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa acuccauuaagg acugggagaggc agag caag ccucaga gcccaggccu


>SEPHS2_otoGar Otolemur garnettii (bushbaby) COVE score: 11.55
>SEPHS2_otoGar Otolemur garnettii (bushbaby) score: 11.55
ccuaccagca ucugacu ucaucucugcug augac auuucucccuug aa aggcuac uaagggcaggg agaa gcagagga aguccca gcgcgcaggc
ccuaccagca ucugacu ucaucucugcug augac auuucucccuug aa aggcuac uaagggcaggg agaa gcagagga aguccca gcgcgcaggc


>SEPHS2_musMus Mus musculus (mouse) COVE score: 22.00
>SEPHS2_musMus Mus musculus (mouse) score: 22.00
aagacuagcc accugac uuggucucugaua augau gucucucccucu aa cucccaguaagg acugggagaggc ugaa caaac cucagag ccaggugucg
aagacuagcc accugac uuggucucugaua augau gucucucccucu aa cucccaguaagg acugggagaggc ugaa caaac cucagag ccaggugucg


>SEPHS2_ratNor Rattus norvegicus (rat) COVE score: 18.62
>SEPHS2_ratNor Rattus norvegicus (rat) score: 18.62
cagccaucua acuuggu cucuguua augac gccucucucugu aa accccacuacgg acugggggaggc agag caa acccag agcccaggcu
cagccaucua acuuggu cucuguua augac gccucucucugu aa accccacuacgg acugggggaggc agag caa acccag agcccaggcu


>SEPHS2_canFam Canis familiaris (dog) COVE score: 20.27
>SEPHS2_canFam Canis familiaris (dog) score: 20.27
ccugcaacca ucugauu uggucucuguua augac guuucucccucu aa accccuuuuagg acugggagaggc agag uaagccccag agcccaa accucagugg
ccugcaacca ucugauu uggucucuguua augac guuucucccucu aa accccuuuuagg acugggagaggc agag uaagccccag agcccaa accucagugg


>SEPHS2_felCat Felis catus (cat) COVE score: 22.33
>SEPHS2_felCat Felis catus (cat) score: 22.33
ccugcgacca ucugauu uggucucuguua augac gucucucccucu aa accccuuuaagg acugggggaggc agag caagccccag agcccaa gccuugaugg
ccugcgacca ucugauu uggucucuguua augac gucucucccucu aa accccuuuaagg acugggggaggc agag caagccccag agcccaa gccuugaugg


>SEPHS2_equCab Equus caballus (horse) COVE score: 21.57
>SEPHS2_equCab Equus caballus (horse) score: 21.57
ccugcagcca ucugacu uggucucuguua augac gucucucccucu aa accccguuaugg acugggagaggc agag caagccccag agcccagg ccuugguggu
ccugcagcca ucugacu uggucucuguua augac gucucucccucu aa accccguuaugg acugggagaggc agag caagccccag agcccagg ccuugguggu


>SEPHS2_bosTau Bos taurus (cow) COVE score: 22.19
>SEPHS2_bosTau Bos taurus (cow) score: 22.19
uccagccacc uuacuug gucucuguua augac gucucucucua aa ccccuuuaagga cugggagaggc agac caaac cccagag accaggauuu
uccagccacc uuacuug gucucuguua augac gucucucucua aa ccccuuuaagga cugggagaggc agac caaac cccagag accaggauuu


>SEPHS2_dasNov Dasypus novemcinctus (armadillo) COVE score: 17.60
>SEPHS2_dasNov Dasypus novemcinctus (armadillo) score: 17.60
acccguaacc accuggc cuggucucuguua augau guuucucccucu aa accccguuaagg acugggagaggc ggag ugagc cccagag cccaggccuu
acccguaacc accuggc cuggucucuguua augau guuucucccucu aa accccguuaagg acugggagaggc ggag ugagc cccagag cccaggccuu
</pre>
</pre>
Line 827: Line 827:
=== SELM1: 18 SECIS insertion sequences ===
=== SELM1: 18 SECIS insertion sequences ===
<pre>
<pre>
>SELM1_homSap Homo sapiens (human) COVE score 27.34
>SELM1_homSap Homo sapiens (human) score 27.34
agagugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuucuaggga uuuguguggau cagau acauac uuggcaa auuuuugagu
agagugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuucuaggga uuuguguggau cagau acauac uuggcaa auuuuugagu


>SELM1_panTro Pan troglodytes (chimp) COVE score 27.93
>SELM1_panTro Pan troglodytes (chimp) score 27.93
agagugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuucuaagga uuuguguggau cagau acauac uuggcaa auuuuugagu
agagugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuucuaagga uuuguguggau cagau acauac uuggcaa auuuuugagu


>SELM1_macMul Macaca mulatta (rhesus) COVE score 27.71
>SELM1_macMul Macaca mulatta (rhesus) score 27.71
agggugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuccuaagga uuuguguggau cagau acauac uuggcaa auuuuugagu
agggugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuccuaagga uuuguguggau cagau acauac uuggcaa auuuuugagu


>SELM1_otoGar Otolemur garnettii (bushbaby) COVE score 28.3
>SELM1_otoGar Otolemur garnettii (bushbaby) score 28.3
gaaacauuca caaaaau uugcauua augaa gacuacacaga aa accuuucagagga uuuguguggau cugau acuuggc aaauuuug aguuuuauau
gaaacauuca caaaaau uugcauua augaa gacuacacaga aa accuuucagagga uuuguguggau cugau acuuggc aaauuuug aguuuuauau


>SELM1_tupBel Tupaia belangeri (tree_shrew) COVE score 24.54
>SELM1_tupBel Tupaia belangeri (tree_shrew) score 24.54
agagggaaac auucaca aagauuugcguua augaa gacugcacaga aa accuuucuaggga uuuguguggau ccgau aau uggcaaa uuuuuguauu
agagggaaac auucaca aagauuugcguua augaa gacugcacaga aa accuuucuaggga uuuguguggau ccgau aau uggcaaa uuuuuguauu


>SELM1_musMus Mus musculus (mouse) COVE score 35.23
>SELM1_musMus Mus musculus (mouse) score 35.23
aauuuaauac uuauaaa gguuugcauua augag gauuacacaga aa accuuuguuaagga cuuguguagau cugau aauuggcaaa uuuuua uuuuaaaagu
aauuuaauac uuauaaa gguuugcauua augag gauuacacaga aa accuuuguuaagga cuuguguagau cugau aauuggcaaa uuuuua uuuuaaaagu


>SELM1_ratNor Rattus norvegicus (rat) COVE score 30.11
>SELM1_ratNor Rattus norvegicus (rat) score 30.11
aauguaauac uuauaaa gguuugcauua augag gauuacacaga aa accuuuguuaaggg uuugugucgau cugau aauuggcaaa uuuuua uuuuuaaaau
aauguaauac uuauaaa gguuugcauua augag gauuacacaga aa accuuuguuaaggg uuugugucgau cugau aauuggcaaa uuuuua uuuuuaaaau


>SELM1_cavPor Cavia porcellus (guinea pig) COVE score 31
>SELM1_cavPor Cavia porcellus (guinea pig) score 31
gaaugaaaug gccacaa aaacuugcauua augag gacuauacaga aa accuuccuaagga uuuguauagau cugau guauggcaaa uuuuugu uuuuacauuc
gaaugaaaug gccacaa aaacuugcauua augag gacuauacaga aa accuuccuaagga uuuguauagau cugau guauggcaaa uuuuugu uuuuacauuc


>SELM1_sorAra Sorex araneus (shrew) COVE score 25.76
>SELM1_sorAra Sorex araneus (shrew) score 25.76
uaagaauaau uugcaca aagauucgcauua augaa ggcuacacagg aa accuuacuaagga uuuguguggau cugau aac uagcaa auuuuugugc
uaagaauaau uugcaca aagauucgcauua augaa ggcuacacagg aa accuuacuaagga uuuguguggau cugau aac uagcaa auuuuugugc


>SELM1_eriEur Erinaceus europaeus (hedgehog) COVE score 26.92
>SELM1_eriEur Erinaceus europaeus (hedgehog) score 26.92
uagcaguacu cacaaag guuugcaucc augaa ggcuacauaga aa accuuacugagga uuuguguagau cugau gcucagcaaa cuucug uguuuuacag
uagcaguacu cacaaag guuugcaucc augaa ggcuacauaga aa accuuacugagga uuuguguagau cugau gcucagcaaa cuucug uguuuuacag


>SELM1_canFam Canis familiaris (dog) COVE score 27.8
>SELM1_canFam Canis familiaris (dog) score 27.8
agaguaucuu cacagag auuugcauua augaa gacuacacaga aa accuucaggagga uuuguguggau cugau auuuagcaa aauuuug uguuucacac
agaguaucuu cacagag auuugcauua augaa gacuacacaga aa accuucaggagga uuuguguggau cugau auuuagcaa aauuuug uguuucacac


>SELM1_felCat Felis catus (cat) COVE score 30.14
>SELM1_felCat Felis catus (cat) score 30.14
gagggaaaca uucacaa cgauuugcauua augaa gacuacacaga aa accuucaugagga uuuguguggau cugau gaua uuuagca aauuuuugug
gagggaaaca uucacaa cgauuugcauua augaa gacuacacaga aa accuucaugagga uuuguguggau cugau gaua uuuagca aauuuuugug


>SELM1_equCab Equus caballus (horse) COVE score 28.65
>SELM1_equCab Equus caballus (horse) score 28.65
agugaaacau ucacaaa gauucgcguua augaa gacuacacaga aa accuuucugagga uuuguguggau cugau auccggcaaa uuuuug ugcuuuacau
agugaaacau ucacaaa gauucgcguua augaa gacuacacaga aa accuuucugagga uuuguguggau cugau auccggcaaa uuuuug ugcuuuacau


>SELM1_bosTau Bos taurus (cow) COVE score 23.97
>SELM1_bosTau Bos taurus (cow) score 23.97
gugaaauauu cacacaa agauuugcauua augaa gacuacacaga aa accuuccugagga uuuguguggac cugau acuuagcaaa uuuuug ugcuuuacau
gugaaauauu cacacaa agauuugcauua augaa gacuacacaga aa accuuccugagga uuuguguggac cugau acuuagcaaa uuuuug ugcuuuacau


>SELM1_dasNov Dasypus novemcinctus (armadillo) COVE score 23.56
>SELM1_dasNov Dasypus novemcinctus (armadillo) score 23.56
agagugaaac auuuaca aagauuugcacua augaa gacuacacaga aa accuuucuaagga uuuguauggau cugau auu uggcaaau uuuuguguuu
agagugaaac auuuaca aagauuugcacua augaa gacuacacaga aa accuuucuaagga uuuguauggau cugau auu uggcaaau uuuuguguuu


>SELM1_loxAfr Loxodonta africana (elephant) COVE score 27.21
>SELM1_loxAfr Loxodonta africana (elephant) score 27.21
agagugaaac auucaca aagauuugcauua augaa gacugcacaga aa accuuuguaagga uuuguguggau cugau auu uggcaag uuuuuguguu
agagugaaac auucaca aagauuugcauua augaa gacugcacaga aa accuuuguaagga uuuguguggau cugau auu uggcaag uuuuuguguu


>SELM1_ornAna Ornithorhynchus anatinus (platypus) COVE score 26.78
>SELM1_ornAna Ornithorhynchus anatinus (platypus) score 26.78
gacugugaaa caugaag acaaugcgcauua augau gacuacacaga aa accuaucaugga uuuguguauau cugau guuu cguguau uuccucaguu
gacugugaaa caugaag acaaugcgcauua augau gacuacacaga aa accuaucaugga uuuguguauau cugau guuu cguguau uuccucaguu


>SELM1_anoCar Anolis carolinensis (lizard) COVE score 31.51
>SELM1_anoCar Anolis carolinensis (lizard) score 31.51
gauuggagga ugccagc aaaauacucuuua augau gacuacaugua aa gccuuuaacaaaagg cauguguaggu cugau guca gaugua cuuuuguuaa
gauuggagga ugccagc aaaauacucuuua augau gacuacaugua aa gccuuuaacaaaagg cauguguaggu cugau guca gaugua cuuuuguuaa
</pre>
</pre>
Line 884: Line 884:
=== MSRB1: 14 SECIS insertion sequences ===
=== MSRB1: 14 SECIS insertion sequences ===
<pre>
<pre>
>MSRB1_homSap Homo sapiens (human) COVE score: 26.23
>MSRB1_homSap Homo sapiens (human) score: 26.23
ccugccagcc gcccugg cccuggucacugc augau ccgcucugguc aa acccuuccaggcc agccagagugg ggau ggu cugugac cugcugggaa
ccugccagcc gcccugg cccuggucacugc augau ccgcucugguc aa acccuuccaggcc agccagagugg ggau ggu cugugac cugcugggaa


>MSRB1_panTro Pan troglodytes (chimp) COVE score: 23.19
>MSRB1_panTro Pan troglodytes (chimp) score: 23.19
ccugccagcc gcccugg cccuggucacugc augau ccgcucugguc aa acccuuccaggcc agccagggugg ggau ggu cugugac cugcugggaa
ccugccagcc gcccugg cccuggucacugc augau ccgcucugguc aa acccuuccaggcc agccagggugg ggau ggu cugugac cugcugggaa


>MSRB1_macMul Macaca mulatta (rhesus) COVE score: 22.02
>MSRB1_macMul Macaca mulatta (rhesus) score: 22.02
ccugccagcc gcccugg cccuggucacugc augau cugcucugguc aa acccuuccaggcc agccagcgugg ggau ggu cugugac cugcugggaa
ccugccagcc gcccugg cccuggucacugc augau cugcucugguc aa acccuuccaggcc agccagcgugg ggau ggu cugugac cugcugggaa


>MSRB1_otoGar Otolemur garnettii (bushbaby) COVE score: 25.09
>MSRB1_otoGar Otolemur garnettii (bushbaby) score: 25.09
uuggccaucu gcuccag cccaagucaaugc augau cuccucuggcu aa auccuuccaggcc agccagggugg ugau guc ugugacc ugcuggggga
uuggccaucu gcuccag cccaagucaaugc augau cuccucuggcu aa auccuuccaggcc agccagggugg ugau guc ugugacc ugcuggggga


>MSRB1_musMus Mus musculus (mouse) COVE score: 23.75
>MSRB1_musMus Mus musculus (mouse) score: 23.75
ccugccaacc gcuccag ccucagucaccga augau cugcucugguc aa auccuucuaugcc agccagggugg ugau gac ccgugac cuuugaggag
ccugccaacc gcuccag ccucagucaccga augau cugcucugguc aa auccuucuaugcc agccagggugg ugau gac ccgugac cuuugaggag


>MSRB1_ratNor Rattus norvegicus (rat) COVE score: 21.64
>MSRB1_ratNor Rattus norvegicus (rat) score: 21.64
cuggccaacc acuccag ccucagucacugu augau cugcucugguu aa auccuucugugcca gcccagggugg ugau gaccugugac cuucgag gagggaggcg
cuggccaacc acuccag ccucagucacugu augau cugcucugguu aa auccuucugugcca gcccagggugg ugau gaccugugac cuucgag gagggaggcg


>MSRB1_cavPor Cavia porcellus (guinea pig) COVE score: 26.14
>MSRB1_cavPor Cavia porcellus (guinea pig) score: 26.14
augaccagcu gcuucag cccuggucaaugc augau cuacucuggcu aa auccuucuaggcc agucagggugg ugau gau cugugac cugcugggga
augaccagcu gcuucag cccuggucaaugc augau cuacucuggcu aa auccuucuaggcc agucagggugg ugau gau cugugac cugcugggga


>MSRB1_oryCun Oryctolagus cuniculus (rabbit) COVE score: 28.41
>MSRB1_oryCun Oryctolagus cuniculus (rabbit) score: 28.41
auuggccccc gccccgg ucacugc augac ccgcucuggcu aa acccuuccagggc agccagggugg ugau ggu cugugac cugcggcggg
auuggccccc gccccgg ucacugc augac ccgcucuggcu aa acccuuccagggc agccagggugg ugau ggu cugugac cugcggcggg


>MSRB1_canFam Canis familiaris (dog) COVE score: 28.62
>MSRB1_canFam Canis familiaris (dog) score: 28.62
guugcuggcu gcugcag cugcagucacuac augau ucacucugguu aa acccuuccaggc agccagagugg ugau gau cugugac cugcuagagg
guugcuggcu gcugcag cugcagucacuac augau ucacucugguu aa acccuuccaggc agccagagugg ugau gau cugugac cugcuagagg


>MSRB1_felCat Felis catus (cat) COVE score: 31.99
>MSRB1_felCat Felis catus (cat) score: 31.99
cucgccggcu gcuccgg cccuggucacuac augau ucacucugguc aa agccuuccaggc agccagagugg ugau gau cugugac ggcuggaggg
cucgccggcu gcuccgg cccuggucacuac augau ucacucugguc aa agccuuccaggc agccagagugg ugau gau cugugac ggcuggaggg


>MSRB1_equCab Equus caballus (horse) COVE score: 24.02
>MSRB1_equCab Equus caballus (horse) score: 24.02
cccagccggc ugcucca gcccagucacugc augau ucacucuggug aa acccuucggggc ggccagagugg ugag gaccug ugacccg cuggaggagc
cccagccggc ugcucca gcccagucacugc augau ucacucuggug aa acccuucggggc ggccagagugg ugag gaccug ugacccg cuggaggagc


>MSRB1_bosTau Bos taurus (cow) COVE score: 27.78
>MSRB1_bosTau Bos taurus (cow) score: 27.78
ugccagcugc cccagcc cagucacucu augau ucucucuggcu aa acccuugcaggc agccagagugg ugau gacccgugac ccgcuggg ggagcaggcg
ugccagcugc cccagcc cagucacucu augau ucucucuggcu aa acccuugcaggc agccagagugg ugau gacccgugac ccgcuggg ggagcaggcg


>MSRB1_ornAna Ornithorhynchus anatinus (platypus) COVE score: 26.32
>MSRB1_ornAna Ornithorhynchus anatinus (platypus) score: 26.32
ucugccccuc cccaccu gguuuucagcauu augac ucgcccugggg aa agcccuccuggag cgccagggcga cgau ggucaccu gaucggg ugggcaggga
ucugccccuc cccaccu gguuuucagcauu augac ucgcccugggg aa agcccuccuggag cgccagggcga cgau ggucaccu gaucggg ugggcaggga


>MSRB1_galGal Gallus gallus (chicken) COVE score: 22
>MSRB1_galGal Gallus gallus (chicken) score: 22
ucuggugcua uucuggg cugggaucauggu augaa uuguccucugu aa auccuccugggau gcgagggugg ggau guu uuguga uccugcugga
ucuggugcua uucuggg cugggaucauggu augaa uuguccucugu aa auccuccugggau gcgagggugg ggau guu uuguga uccugcugga
</pre>
</pre>


=== TXNRD1: 17 SECIS insertion sequences ===
=== TXNRD1: 17 SECIS insertion sequences ===
<pre>
<pre>
>TXNRD1_homSap Homo sapiens (human) COVE score: 25.36
>TXNRD1_homSap Homo sapiens (human) score: 25.36
auuuggcagg gcaucga agggaugcaucc augaa gucaccagucuc aa gcccaugugg uaggcggugau ggaa caacug ucaaauc aguuuuagca
auuuggcagg gcaucga agggaugcaucc augaa gucaccagucuc aa gcccaugugg uaggcggugau ggaa caacug ucaaauc aguuuuagca


>TXNRD1_panTro Pan troglodytes (chimp) COVE score: 25.36
>TXNRD1_panTro Pan troglodytes (chimp) score: 25.36
auuuggcagg gcaucga agggaugcaucc augaa gucaccagucuc aa gcccaugugg uaggcggugau ggaa caacug ucaaauc aguuuuagca
auuuggcagg gcaucga agggaugcaucc augaa gucaccagucuc aa gcccaugugg uaggcggugau ggaa caacug ucaaauc aguuuuagca


>TXNRD1_otoGar Otolemur garnettii (bushbaby) COVE score: 23.42
>TXNRD1_otoGar Otolemur garnettii (bushbaby) score: 23.42
aucggcagug caucgac gggaugcgucc augaa gucaccagccuc aa gccugugugg ugggcagugau ggaa caacu guccaau caguuucuau
aucggcagug caucgac gggaugcgucc augaa gucaccagccuc aa gccugugugg ugggcagugau ggaa caacu guccaau caguuucuau


>TXNRD1_tupBel Tupaia belangeri (tree_shrew) COVE score: 25.13
>TXNRD1_tupBel Tupaia belangeri (tree_shrew) score: 25.13
ucuuggcagc gcaucag agggaugcgucc augaa gucaccagccuc aa gcccgugcgg ugggcggugau ggaa cgacug ccagauc aguuucagca
ucuuggcagc gcaucag agggaugcgucc augaa gucaccagccuc aa gcccgugcgg ugggcggugau ggaa cgacug ccagauc aguuucagca


>TXNRD1_musMus Mus musculus (mouse) COVE score: 27.9
>TXNRD1_musMus Mus musculus (mouse) score: 27.9
aucuggcaga gcaucac aggcaugcgucc augaa gucacuggccuc aa gcccaagug gugggcagugac agaa gagcu gccgggu cuguugagcu
aucuggcaga gcaucac aggcaugcgucc augaa gucacuggccuc aa gcccaagug gugggcagugac agaa gagcu gccgggu cuguugagcu


>TXNRD1_ratNor Rattus norvegicus (rat) COVE score: 28.03
>TXNRD1_ratNor Rattus norvegicus (rat) score: 28.03
uucggcagag caucacg gugcgucc augaa gucacuagccuc aa gcccaagugg ugggcagugac agaa agc ugucgau cuguuggguu
uucggcagag caucacg gugcgucc augaa gucacuagccuc aa gcccaagugg ugggcagugac agaa agc ugucgau cuguuggguu


>TXNRD1_cavPor Cavia porcellus (guinea_pig) COVE score: 23.88
>TXNRD1_cavPor Cavia porcellus (guinea_pig) score: 23.88
gcggcggcac cguaggg ugcgucc augag gucaccagccuc aa gcccgaggg ugggcggugac ggau cgc gccgcg uggcucagcu
gcggcggcac cguaggg ugcgucc augag gucaccagccuc aa gcccgaggg ugggcggugac ggau cgc gccgcg uggcucagcu


>TXNRD1_eriEur Erinaceus europaeus (hedgehog) COVE score: 26.25
>TXNRD1_eriEur Erinaceus europaeus (hedgehog) score: 26.25
ugucagcaga gcaucaa agggaugcgucc augaa gucaccagccuc aa gcccgugcggg ugggcagugac ggaa cacug ucgaagc aguuucaaca
ugucagcaga gcaucaa agggaugcgucc augaa gucaccagccuc aa gcccgugcggg ugggcagugac ggaa cacug ucgaagc aguuucaaca


>TXNRD1_canFam Canis familiaris (dog) COVE score: 24.54
>TXNRD1_canFam Canis familiaris (dog) score: 24.54
auucggcaug caucggc guggugcgucc augaa gucacuggccuc aa gccaugcg gugggcagugau ggag caac ugucgag caguuuuagu
auucggcaug caucggc guggugcgucc augaa gucacuggccuc aa gccaugcg gugggcagugau ggag caac ugucgag caguuuuagu


>TXNRD1_felCat Felis catus (cat) COVE score: 24.14
>TXNRD1_felCat Felis catus (cat) score: 24.14
acucggcagc gcaucgg agggcgcgucc augaa gucaccggcccc aa gcccccgcg gugggcggugau ggaa caagu gccgagc aguuuuagcg
acucggcagc gcaucgg agggcgcgucc augaa gucaccggcccc aa gcccccgcg gugggcggugau ggaa caagu gccgagc aguuuuagcg


>TXNRD1_equCab Equus caballus (horse) COVE score: 21.76
>TXNRD1_equCab Equus caballus (horse) score: 21.76
acucggcagu gcaucga agggaugcgucc augaa gucacuggccuc aa agcccaugug gugggcggugau ggaa cagcug ucgaagc aguuuuagca
acucggcagu gcaucga agggaugcgucc augaa gucacuggccuc aa agcccaugug gugggcggugau ggaa cagcug ucgaagc aguuuuagca


>TXNRD1_loxAfr Loxodonta africana (elephant) COVE score: 22.55
>TXNRD1_loxAfr Loxodonta africana (elephant) score: 22.55
auuggcagcg caucgag ggaugcaucc augaa gucacuggccuc aa gcccaugug gggggcggugau ggaa cagcu gucgaau cagcuuuggc
auuggcagcg caucgag ggaugcaucc augaa gucacuggccuc aa gcccaugug gggggcggugau ggaa cagcu gucgaau cagcuuuggc


>TXNRD1_echTel Echinops telfairi (tenrec) COVE score: 19.5
>TXNRD1_echTel Echinops telfairi (tenrec) score: 19.5
guggcagugc aucaaga gaugcguuc augaa aucgcuugcccc aa gcccga guggcgggcag cgau ggaaca ucugucu caucaguuuc
guggcagugc aucaaga gaugcguuc augaa aucgcuugcccc aa gcccga guggcgggcag cgau ggaaca ucugucu caucaguuuc


>TXNRD1_monDom Monodelphis domestica (opossum) COVE score: 23.46
>TXNRD1_monDom Monodelphis domestica (opossum) score: 23.46
ggcucgcggu gcaucgg ugagaugcguuc augaa gucgcugccug aa gcccauaucccgugg uggguggugac cgaa agaaccg ccggcc uccguuuuau
ggcucgcggu gcaucgg ugagaugcguuc augaa gucgcugccug aa gcccauaucccgugg uggguggugac cgaa agaaccg ccggcc uccguuuuau


>TXNRD1_ornAna Ornithorhynchus anatinus (platypus) COVE score: 18.89
>TXNRD1_ornAna Ornithorhynchus anatinus (platypus) score: 18.89
aggagugcac ccaaggg cugcauuu augaa gucagagccaa aa gccagcauuuugcgg uuggcugugau ggaa aaa cuccug ccacaguuuu
aggagugcac ccaaggg cugcauuu augaa gucagagccaa aa gccagcauuuugcgg uuggcugugau ggaa aaa cuccug ccacaguuuu


>TXNRD1_anoCar Anolis carolinensis (lizard) COVE score: 32.53
>TXNRD1_anoCar Anolis carolinensis (lizard) score: 32.53
uggcaaggca uuguuca agaugcuucc augaa gucacagucua aa accagugcuuucugg uaggcagugau ggaa aga uugcugg cacaacuuga
uggcaaggca uuguuca agaugcuucc augaa gucacagucua aa accagugcuuucugg uaggcagugau ggaa aga uugcugg cacaacuuga


>TXNRD1_galGal Gallus gallus (chicken) COVE score: 26.64
>TXNRD1_galGal Gallus gallus (chicken) score: 26.64
uagcagggca uuucaca caugcuuuc augaa aucacagccug aa gccugcacugucugg ugggcagugau ggaa gaacu gcugaca cagcugaaca
uagcagggca uuucaca caugcuuuc augaa aucacagccug aa gccugcacugucugg ugggcagugau ggaa gaacu gcugaca cagcugaaca
</pre>
</pre>
Line 987: Line 983:
=== TXNRD3: 9 SECIS insertion sequences (problematic) ===
=== TXNRD3: 9 SECIS insertion sequences (problematic) ===
<pre>
<pre>
>TXNRD3_homSap Homo sapiens (human) COVE score: 19.10
>TXNRD3_homSap Homo sapiens (human) score: 19.10
gacagcgaga agcagug ggacugcuucc uugac gccuuagcuu gg agccccguuaugaggu gagccaaggc ugac ucu cgcaagc caggacugag
gacagcgaga agcagug ggacugcuucc uugac gccuuagcuu gg agccccguuaugaggu gagccaaggc ugac ucu cgcaagc caggacugag


>TXNRD3_panTro Pan troglodytes (chimp) COVE score: 19.10  
>TXNRD3_panTro Pan troglodytes (chimp) score: 19.10  
agcagugggc GACAGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUU GG AGCCCCGUUAUGAGGU GAGCCAAGGC UGAC UCU CGCAAGC CAGGACUGAG
agcagugggc GACAGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUU GG AGCCCCGUUAUGAGGU GAGCCAAGGC UGAC UCU CGCAAGC CAGGACUGAG


>TXNRD3_macMul Macaca mulatta (rhesus) COVE score: 17.86  
>TXNRD3_macMul Macaca mulatta (rhesus) score: 17.86  
GACuGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUU GG AGCCCuGUUgUGAGGU GAGCCAAGGC cGAC UCU CGCAAGC CAGGACUcAG
GACuGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUU GG AGCCCuGUUgUGAGGU GAGCCAAGGC cGAC UCU CGCAAGC CAGGACUcAG


>TXNRD3_calJac Callithrix jacchus (marmoset) COVE score: 25.26  
>TXNRD3_calJac Callithrix jacchus (marmoset) score: 25.26  
GACuGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUc Ga AGCCCuGUUAcGAGGU GAGCCAAGGC UGAu UCU CGCAAGC gAGGACUGAG
GACuGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUc Ga AGCCCuGUUAcGAGGU GAGCCAAGGC UGAu UCU CGCAAGC gAGGACUGAG


>TXNRD3_musMus Mus musculus (mouse) COVE score: 21.86  
>TXNRD3_musMus Mus musculus (mouse) score: 21.86  
CUGACGGCAU GCAGCAG CCAGGCUGCUUCC UUGAC ACCUUGGCUC GG AACCUGCAGAGGU GAGCCAAGGC CGAC UUC UGCACGU CAGCCUCGAC
CUGACGGCAU GCAGCAG CCAGGCUGCUUCC UUGAC ACCUUGGCUC GG AACCUGCAGAGGU GAGCCAAGGC CGAC UUC UGCACGU CAGCCUCGAC


>TXNRD3_ratNor Rattus norvegicus (rat) COVE score: 25.37  
>TXNRD3_ratNor Rattus norvegicus (rat) score: 25.37  
cugauggcgu gcagcag ccaggcugcaucc uugac gccuuggcuc gg aaccugcagagg ugagccaaggc cgac ucc ugcacgu cagccucgac
cugauggcgu gcagcag ccaggcugcaucc uugac gccuuggcuc gg aaccugcagagg ugagccaaggc cgac ucc ugcacgu cagccucgac


>TXNRD3_canFam Canis familiaris (dog) COVE score: 26.93
>TXNRD3_canFam Canis familiaris (dog) score: 26.93
GCUGGCUGGA GAGGCAG GCAGGCUGCCUCC UUGAC GCCUUAGCUC GG AACCGCUGUGAGG UGAGCUAAGGC CGAU GUC CUCCAU GCCAGGCCAG
GCUGGCUGGA GAGGCAG GCAGGCUGCCUCC UUGAC GCCUUAGCUC GG AACCGCUGUGAGG UGAGCUAAGGC CGAU GUC CUCCAU GCCAGGCCAG


>TXNRD3_felCat Felis catus (cat) COVE score: 20.14
>TXNRD3_felCat Felis catus (cat) score: 20.14
CUGGCUgGGA GAGGCAG GucGGCUGCCUCC UUGAC GuCUUAGCUC GG AgcccgaUGUGAGG UGAGCUAAGGC CGAU Ggu cuuccac gucagaaucg
CUGGCUgGGA GAGGCAG GucGGCUGCCUCC UUGAC GuCUUAGCUC GG AgcccgaUGUGAGG UGAGCUAAGGC CGAU Ggu cuuccac gucagaaucg
 
>TXNRD3_bosTau Bos taurus (cow) COVE score: 12.55
>TXNRD3_bosTau Bos taurus (cow) score: 12.55
GGCUGACGGG AGGGCAG ACUCGCUGCCUCC UUGAC GUCUUCGCUC AG AGCCGCCAGGU GAGCCAAGAC CGAC CUC UGCCCA CCAGCUCCUC
GGCUGACGGG AGGGCAG ACUCGCUGCCUCC UUGAC GUCUUCGCUC AG AGCCGCCAGGU GAGCCAAGAC CGAC CUC UGCCCA CCAGCUCCUC
</pre>
</pre>
Line 1,017: Line 1,013:
=== TXNRD2: 10 SECIS insertion sequences ===
=== TXNRD2: 10 SECIS insertion sequences ===
<pre>
<pre>
>TXNRD2 homSap Homo sapiens (human) COVE score: 31.00
>TXNRD2 homSap Homo sapiens (human) score: 31.00
cacccccccc caggcuc cuggugccagaug augac gaccugggugg aa accuacccugugg gcacccauguc cgag ccccc uggcauu ucugcaaugc
cacccccccc caggcuc cuggugccagaug augac gaccugggugg aa accuacccugugg gcacccauguc cgag ccccc uggcauu ucugcaaugc


>TXNRD2 panTro Pan troglodytes (chimp) COVE score: 31.00
>TXNRD2 panTro Pan troglodytes (chimp) score: 31.00
ggcacccccc caggcuc cuggugccagaug augac gaccugggugg aa accuacccugugg gcacccauguc cgag ccccc uggcauu ucugcauugc
ggcacccccc caggcuc cuggugccagaug augac gaccugggugg aa accuacccugugg gcacccauguc cgag ccccc uggcauu ucugcauugc


>TXNRD2 tupBel Tupaia belangeri (tree shrew) COVE score: 36.55
>TXNRD2 tupBel Tupaia belangeri (tree shrew) score: 36.55
cucccucccc aggcccc cgaugccagaug augac ggccuggacag aa acccacccuguggg cugcccagguc ugaa cccuccc uggugucu uuggggugua
cucccucccc aggcccc cgaugccagaug augac ggccuggacag aa acccacccuguggg cugcccagguc ugaa cccuccc uggugucu uuggggugua


>TXNRD2 musMus Mus musculus (mouse) COVE score: 36.94
>TXNRD2 musMus Mus musculus (mouse) score: 36.94
gccagccucu gacacuc ccagcgucagaug augau ggccugggcag aa accccauguggg ccgcccagguu ugaa ccccu ggcauuu cuagagcacu
gccagccucu gacacuc ccagcgucagaug augau ggccugggcag aa accccauguggg ccgcccagguu ugaa ccccu ggcauuu cuagagcacu


>TXNRD2 ratNor Rattus norvegicus (rat) COVE score: 34.71
>TXNRD2 ratNor Rattus norvegicus (rat) score: 34.71
cagccuucac acacugc cagugucagaug augac ggccugugcag aa acccccacguggg cugcccagguu ugaa ccccug gcauuu cuggagugcu
cagccuucac acacugc cagugucagaug augac ggccugugcag aa acccccacguggg cugcccagguu ugaa ccccug gcauuu cuggagugcu


>TXNRD2 cavPor Cavia porcellus (guinea pig) COVE score: 34.41
>TXNRD2 cavPor Cavia porcellus (guinea pig) score: 34.41
ucuggccccc caggucc ccagugccaguug augau ggccugggcag aa acccacccuguggg caguccauguc ugaa cuccc uggcauu ucuggagugc
ucuggccccc caggucc ccagugccaguug augau ggccugggcag aa acccacccuguggg caguccauguc ugaa cuccc uggcauu ucuggagugc


>TXNRD2 eriEur Erinaceus europaeus (hedgehog) COVE score: 34.68
>TXNRD2 eriEur Erinaceus europaeus (hedgehog) score: 34.68
ccagccccac caggccc ccgaugccagaua augau gacuugugcag aa acccacccggg cugcccauguc ugag ccucug uggcauu cuggagugua
ccagccccac caggccc ccgaugccagaua augau gacuugugcag aa acccacccggg cugcccauguc ugag ccucug uggcauu cuggagugua


>TXNRD2 canFam Canis familiaris (dog) COVE score: 34.36
>TXNRD2 canFam Canis familiaris (dog) score: 34.36
accagccccg ccaggcc ccgaugccagaag augac gacgugugcag aa accccccuguggg cugcccgcguc cgag cccccuggc guuucugg aauguaaaua
accagccccg ccaggcc ccgaugccagaag augac gacgugugcag aa accccccuguggg cugcccgcguc cgag cccccuggc guuucugg aauguaaaua


>TXNRD2 equCab Equus caballus (horse) COVE score: 31.37
>TXNRD2 equCab Equus caballus (horse) score: 31.37
ccagcccugc cagguuc ccgaugccagacg augac gaccugcgcgg aa acccacccuguggg cugcccacguc cgag ccccc uggcauu ucugaagugc
ccagcccugc cagguuc ccgaugccagacg augac gaccugcgcgg aa acccacccuguggg cugcccacguc cgag ccccc uggcauu ucugaagugc


>TXNRD2 echTel Echinops telfairi (tenrec) COVE score: 37.41
>TXNRD2 echTel Echinops telfairi (tenrec) score: 37.41
cccuugcccc caccuca gcgccagaug augaa gacaugugcag aa acccagcccguggg cugcccauguc ugag ccccc ugacgu uucuggagug
cccuugcccc caccuca gcgccagaug augaa gacaugugcag aa acccagcccguggg cugcccauguc ugag ccccc ugacgu uucuggagug
</pre>
</pre>
Line 1,050: Line 1,046:
=== SELS: 20 SECIS insertion sequences ===
=== SELS: 20 SECIS insertion sequences ===
<pre>
<pre>
>SELS_homSap Homo sapiens (human) COVE score 36.61
>SELS_homSap Homo sapiens (human) score 36.61
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu


>SELS_panTro Pan troglodytes (chimp) COVE score 36.61
>SELS_panTro Pan troglodytes (chimp) score 36.61
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu


>SELS_macMul Macaca mulatta (rhesus) COVE score 36.61
>SELS_macMul Macaca mulatta (rhesus) score 36.61
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu


>SELS_otoGar Otolemur garnettii (bushbaby) COVE score 38.23
>SELS_otoGar Otolemur garnettii (bushbaby) score 38.23
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau acaga caguuga ugggguuugu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau acaga caguuga ugggguuugu


>SELS_tupBel Tupaia belangeri (tree_shrew) COVE score 40.14
>SELS_tupBel Tupaia belangeri (tree_shrew) score 40.14
gagaacaguc ucuguga cagggugcgucga augau gucuuccuuau aa auggugagcccacca cugaggaguac ugau gcaga caguuga caggguuugu
gagaacaguc ucuguga cagggugcgucga augau gucuuccuuau aa auggugagcccacca cugaggaguac ugau gcaga caguuga caggguuugu


>SELS_musMus Mus musculus (mouse) COVE score 41.68
>SELS_musMus Mus musculus (mouse) score 41.68
caggaugguc ucuguga cgggaugcguuga augau gucuuccuuau aa auggugaacccacca gugaggauuac ugau guu cacagu ugacgggguu
caggaugguc ucuguga cgggaugcguuga augau gucuuccuuau aa auggugaacccacca gugaggauuac ugau guu cacagu ugacgggguu


>SELS_ratNor Rattus norvegicus (rat) COVE score 40.42
>SELS_ratNor Rattus norvegicus (rat) score 40.42
cagggugguc ucuguga caggaugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau gua cacagu ugaugggguu
cagggugguc ucuguga caggaugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau gua cacagu ugaugggguu


>SELS_cavPor Cavia porcellus (guinea_pig) COVE score 40.42
>SELS_cavPor Cavia porcellus (guinea_pig) score 40.42
aaggacaguc ucuguga cgagcugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau gcaga caguuga ugggguuuau
aaggacaguc ucuguga cgagcugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau gcaga caguuga ugggguuuau


>SELS_canFam Canis familiaris (dog) COVE score 39.26
>SELS_canFam Canis familiaris (dog) score 39.26
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa acggugagcccacca gcgaggauuac ugau gcaga caguuga ugggguuguu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa acggugagcccacca gcgaggauuac ugau gcaga caguuga ugggguuguu


>SELS_felCat Felis catus (cat) COVE score 41.01
>SELS_felCat Felis catus (cat) score 41.01
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa auggugagcccacca gcgaggauuac ugau gcaga caguuga ugggguuguu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa auggugagcccacca gcgaggauuac ugau gcaga caguuga ugggguuguu


>SELS_equCab Equus caballus (horse) COVE score 41.01
>SELS_equCab Equus caballus (horse) score 41.01
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa auggugagcccacca gcgaggauuac ugau gcaga caguuga uggguuguuu
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa auggugagcccacca gcgaggauuac ugau gcaga caguuga uggguuguuu


>SELS_bosTau Bos taurus (cow) COVE score 41.15
>SELS_bosTau Bos taurus (cow) score 41.15
uaggacaguc ucuguga cagcuugcguuga augau gucuuccuugu aa auggugagcccacca gcaaggauuac ugau gcaga caguuga ugggguuguu
uaggacaguc ucuguga cagcuugcguuga augau gucuuccuugu aa auggugagcccacca gcaaggauuac ugau gcaga caguuga ugggguuguu


>SELS_eriEur Erinaceus europaeus (hedgehog) COVE score 36.87
>SELS_eriEur Erinaceus europaeus (hedgehog) score 36.87
cucucuguga uggguug cguugg augau gucuuccuuguc aa uggugaacccacca gcgaggaucac ugau gcag acaguug augggguugu
cucucuguga uggguug cguugg augau gucuuccuuguc aa uggugaacccacca gcgaggaucac ugau gcag acaguug augggguugu


>SELS_sorAra Sorex araneus (shrew) COVE score 35.70
>SELS_sorAra Sorex araneus (shrew) score 35.70
ugccgggccc gucucug ugauaggcgacga augac gucguccucgg aa auggugugccacca gcgaggaccac cgau gaagacacu ccugggc gccccccccc
ugccgggccc gucucug ugauaggcgacga augac gucguccucgg aa auggugugccacca gcgaggaccac cgau gaagacacu ccugggc gccccccccc


>SELS_dasNov Dasypus novemcinctus (armadillo) COVE score 35.89
>SELS_dasNov Dasypus novemcinctus (armadillo) score 35.89
uagaacaguc ucuguga cagguugcguuga augau gucuuccuuau aa aauggugaacccacca gugaggauuac ugau aauaga caguuga ugggguuugu
uagaacaguc ucuguga cagguugcguuga augau gucuuccuuau aa aauggugaacccacca gugaggauuac ugau aauaga caguuga ugggguuugu


>SELS_echTel Echinops telfairi (tenrec) COVE score 38.43
>SELS_echTel Echinops telfairi (tenrec) score 38.43
uagaacaguc ucuguga cagguugcguuga augaa gucuuccuuau aa auggugaacucacca gugaggauuac ugau aaaga caguuga ugagguuugu
uagaacaguc ucuguga cagguugcguuga augaa gucuuccuuau aa auggugaacucacca gugaggauuac ugau aaaga caguuga ugagguuugu


>SELS_monDom Monodelphis domestica (opossum) COVE score 40.64
>SELS_monDom Monodelphis domestica (opossum) score 40.64
uagaugaguc ucuguga caggcugcgcaga augau gucuuccuuau aa auggugagcucacca gugaggauuac ugau gauagauag uuguugg uguuuuuuuc
uagaugaguc ucuguga caggcugcgcaga augau gucuuccuuau aa auggugagcucacca gugaggauuac ugau gauagauag uuguugg uguuuuuuuc


>SELS_ornAna Ornithorhynchus anatinus (platypus) COVE score 33.47
>SELS_ornAna Ornithorhynchus anatinus (platypus) score 33.47
ucaauaaguc ucuguga caggcggcauuga augau gucuuccuugu aa auggugaaacccacca gugaggauuac ugau aua gacagg agaugguauu
ucaauaaguc ucuguga caggcggcauuga augau gucuuccuugu aa auggugaaacccacca gugaggauuac ugau aua gacagg agaugguauu


>SELS_anoCar Anolis carolinensis (lizard) COVE score 25.44
>SELS_anoCar Anolis carolinensis (lizard) score 25.44
gaaacucccu guaacaa gcagcaacaa augac gugguccuuau aa augguggacacauca cugaggaccuc cgaa gauaagacag cugauug gggacaguuc
gaaacucccu guaacaa gcagcaacaa augac gugguccuuau aa augguggacacauca cugaggaccuc cgaa gauaagacag cugauug gggacaguuc


>SELS_galGal Gallus gallus (chicken) COVE score 35.60
>SELS_galGal Gallus gallus (chicken) score 35.60
cgggagaguc ucuguga caagcugcucugu augau guuuuccuuau aa augguaaacaaacca augaggauuac ugau gcua gacagca gauggggguu
cgggagaguc ucuguga caagcugcucugu augau guuuuccuuau aa augguaaacaaacca augaggauuac ugau gcua gacagca gauggggguu
</pre>
</pre>
Line 1,113: Line 1,109:
=== SELT: 21 SECIS insertion sequences ===
=== SELT: 21 SECIS insertion sequences ===
<pre>
<pre>
>SELT_homSap Homo sapiens (human) COVE score: 39.15
>SELT_homSap Homo sapiens (human) score: 39.15
gaucauugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
gaucauugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_panTro Pan troglodytes (chimp) COVE score: 39.15
>SELT_panTro Pan troglodytes (chimp) score: 39.15
gaucauuuca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
gaucauuuca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_macMul Macaca mulatta (rhesus) COVE score: 39.15
>SELT_macMul Macaca mulatta (rhesus) score: 39.15
gaucauugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
gaucauugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_otoGar Otolemur garnettii (bushbaby) COVE score: 39.15
>SELT_otoGar Otolemur garnettii (bushbaby) score: 39.15
gauuuuugca agagcag cgugacugacagu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
gauuuuugca agagcag cgugacugacagu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_musMus Mus musculus (mouse) COVE score: 39.15
>SELT_musMus Mus musculus (mouse) score: 39.15
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau guuucuugg caggcuc guuguaccuc
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau guuucuugg caggcuc guuguaccuc


>SELT_ratNor Rattus norvegicus (rat) COVE score: 39.15
>SELT_ratNor Rattus norvegicus (rat) score: 39.15
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau guuucuugg caggcuc guuguaccuc
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau guuucuugg caggcuc guuguaccuc


>SELT_cavPor Cavia porcellus (guinea_pig) COVE score: 39.15
>SELT_cavPor Cavia porcellus (guinea_pig) score: 39.15
aauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uuuuug gcaggaucgu
aauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uuuuug gcaggaucgu


>SELT_oryCun Oryctolagus cuniculus (rabbit) COVE score: 39.15
>SELT_oryCun Oryctolagus cuniculus (rabbit) score: 39.15
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uuuuug gcaggcucgu
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uuuuug gcaggcucgu


>SELT_canFam Canis familiaris (dog) COVE score: 39.15
>SELT_canFam Canis familiaris (dog) score: 39.15
auuuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
auuuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_felCat Felis catus (cat) COVE score: 39.15
>SELT_felCat Felis catus (cat) score: 39.15
auuuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
auuuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_equCab Equus caballus (horse) COVE score: 38.49
>SELT_equCab Equus caballus (horse) score: 38.49
gacuuuugca agagcag cguggcugacagu augaa ggccuguacug aa gacagcaagcugu uaguacagacc cgau gcu uucuug gcaggcucgu
gacuuuugca agagcag cguggcugacagu augaa ggccuguacug aa gacagcaagcugu uaguacagacc cgau gcu uucuug gcaggcucgu


>SELT_bosTau Bos taurus (cow) COVE score: 39.15
>SELT_bosTau Bos taurus (cow) score: 39.15
gauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
gauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_eriEur Erinaceus europaeus (hedgehog) COVE score: 39.15
>SELT_eriEur Erinaceus europaeus (hedgehog) score: 39.15
gauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu
gauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu


>SELT_sorAra Sorex araneus (shrew) COVE score: 35.80
>SELT_sorAra Sorex araneus (shrew) score: 35.80
ggauucucca agagcag cgcggcugcccuc augaa ggccugcacug aa gacagcagcugu uggugcaggcu ggau cuuccugg caggcuc guuguaccuc
ggauucucca agagcag cgcggcugcccuc augaa ggccugcacug aa gacagcagcugu uggugcaggcu ggau cuuccugg caggcuc guuguaccuc


>SELT_loxAfr Loxodonta africana (elephant) COVE score: 36.15
>SELT_loxAfr Loxodonta africana (elephant) score: 36.15
gauuuuuuca agagcag cgugacugacauu augaa ggccuguacug aa gacagcgagcugu uaguacagacc agau gcu uuuuug gcaggcgcgu
gauuuuuuca agagcag cgugacugacauu augaa ggccuguacug aa gacagcgagcugu uaguacagacc agau gcu uuuuug gcaggcgcgu


>SELT_monDom Monodelphis domestica (opossum) COVE score: 36.95
>SELT_monDom Monodelphis domestica (opossum) score: 36.95
auuuuugcga gagcagc gugguuggcacca augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau acuu acuuugc agccucguug
auuuuugcga gagcagc gugguuggcacca augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau acuu acuuugc agccucguug


>SELT_ornAna Ornithorhynchus anatinus (platypus) COVE score: 36.17
>SELT_ornAna Ornithorhynchus anatinus (platypus) score: 36.17
gaucuuucua agggcaa cgugauugaaacu augaa ggccuguacug aa ggcagcaaacugu uaguacagacc agau guuccu uugcagu cucguuguac
gaucuuucua agggcaa cgugauugaaacu augaa ggccuguacug aa ggcagcaaacugu uaguacagacc agau guuccu uugcagu cucguuguac


>SELT_anoCar Anolis carolinensis (lizard) COVE score: 34.03
>SELT_anoCar Anolis carolinensis (lizard) score: 34.03
acaguuuuga aaggcaa caugaacgaaaua augaa ggucuguacug aa gacagcaugcugu uggugcagacu ggau acuucuc cucgccuu cauguuguug
acaguuuuga aaggcaa caugaacgaaaua augaa ggucuguacug aa gacagcaugcugu uggugcagacu ggau acuucuc cucgccuu cauguuguug


>SELT_galGal Gallus gallus (chicken) COVE score: 38.05
>SELT_galGal Gallus gallus (chicken) score: 38.05
gugauuucca aggccgc gugucucggacca augaa ggccuguacug aa gacagcuugcugu ugguacagacu ggau gcuucucuu gcaguc acguugugcc
gugauuucca aggccgc gugucucggacca augaa ggccuguacug aa gacagcuugcugu ugguacagacu ggau gcuucucuu gcaguc acguugugcc


>SELT_danRer Danio rerio (zebrafish) COVE score: 34.86
>SELT_danRer Danio rerio (zebrafish) score: 34.86
ccggucagcg ggacugu ggacuguggcaua augaa ggccugcgcugc aa acagcacacug uuggcacaggcu ggau gcu cagccac cacacacacu
ccggucagcg ggacugu ggacuguggcaua augaa ggccugcgcugc aa acagcacacug uuggcacaggcu ggau gcu cagccac cacacacacu


>SELT_tetNig Tetraodon nigroviridis (pufferfish) COVE score: 33.32
>SELT_tetNig Tetraodon nigroviridis (pufferfish) score: 33.32
ggugggucuc ccugugg gcugugagguu augaa ggucugugcug aa ggcaggacgacugc uagcucagacu ggau gucccca ucacug uucaccgugc
ggugggucuc ccugugg gcugugagguu augaa ggucugugcug aa ggcaggacgacugc uagcucagacu ggau gucccca ucacug uucaccgugc
</pre>
</pre>
Line 1,179: Line 1,175:
=== SELO: 5 SECIS insertion sequences ===
=== SELO: 5 SECIS insertion sequences ===
<pre>
<pre>
>SELO_homSap Homo sapiens (human) COVE score: 25.77
>SELO_homSap Homo sapiens (human) score: 25.77
cugcccuggc ccaugca cacccgucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccggcuc agcagug cagccugguc
cugcccuggc ccaugca cacccgucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccggcuc agcagug cagccugguc


>SELO_panTro Pan troglodytes (chimp) COVE score: 25.77
>SELO_panTro Pan troglodytes (chimp) score: 25.77
cugcccuggc ccaugca cacccgucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccggcuc agcagug cagcuugguc
cugcccuggc ccaugca cacccgucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccggcuc agcagug cagcuugguc


>SELO_macMul Macaca mulatta (rhesus) COVE score: 25.77
>SELO_macMul Macaca mulatta (rhesus) score: 25.77
cugccugggc ccaugca caccugucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccagcuc agcagug cagccugguc
cugccugggc ccaugca caccugucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccagcuc agcagug cagccugguc


>SELO_monDom Monodelphis domestica (opossum) COVE score: 24.43
>SELO_monDom Monodelphis domestica (opossum) score: 24.43
gucuggggcc uccccga uggcugcuucucc augaa ggcagagaugu cc agucggcuccga cccgucucuguc cgac gcugac ucggca gcccgagcuc
gucuggggcc uccccga uggcugcuucucc augaa ggcagagaugu cc agucggcuccga cccgucucuguc cgac gcugac ucggca gcccgagcuc


>SELO_takRub Takifugu rubripes (fugu) COVE score: 20.04
>SELO_takRub Takifugu rubripes (fugu) score: 20.04
ccugcuugcc ccgaguu cuaccugcgaaua augac gacucagacaa ca agucugccagugac cugucugacuc ugaa cugugu ggugucg ccucagcaaa
ccugcuugcc ccgaguu cuaccugcgaaua augac gacucagacaa ca agucugccagugac cugucugacuc ugaa cugugu ggugucg ccucagcaaa
</pre>
</pre>
Line 1,197: Line 1,193:
=== SELV: 10 SECIS insertion sequences ===
=== SELV: 10 SECIS insertion sequences ===
<pre>
<pre>
>SELV_homSap Homo sapiens (human) COVE score: 34.00
>SELV_homSap Homo sapiens (human) score: 34.00
uuucucuccc aucuuag gagucucagcugg augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cuggggugag
uuucucuccc aucuuag gagucucagcugg augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cuggggugag


>SELV_panTro Pan troglodytes (chimp) COVE score: 34.00
>SELV_panTro Pan troglodytes (chimp) score: 34.00
uuucucuccc aucuuag gagucucagcggg augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cuggggugag
uuucucuccc aucuuag gagucucagcggg augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cuggggugag


>SELV_otoGar Otolemur garnettii (bushbaby) COVE score: 27.28
>SELV_otoGar Otolemur garnettii (bushbaby) score: 27.28
cuucucuccc aucucag gagccucgguagg augac gagaagggcug aa auauugccaugu cagguccuuuu cugau ggug gcuggga cugggguacg
cuucucuccc aucucag gagccucgguagg augac gagaagggcug aa auauugccaugu cagguccuuuu cugau ggug gcuggga cugggguacg


>SELV_musMus Mus musculus (mouse) COVE score: 33.37
>SELV_musMus Mus musculus (mouse) score: 33.37
cucucucccc aucucag gagccucagcagg augau gagaagggcug aa augcugccaaac cagguccuuuu cugau ggug gcugggg cuuggguggg
cucucucccc aucucag gagccucagcagg augau gagaagggcug aa augcugccaaac cagguccuuuu cugau ggug gcugggg cuuggguggg


>SELV_ratNor Rattus norvegicus (rat) COVE score: 33.37
>SELV_ratNor Rattus norvegicus (rat) score: 33.37
uucucucccu gucucag gaaccucagcggg augau gagaagggcug aa augcugccaaac cagguccuuuu cugau ggug gcuggggc uugguuaggg
uucucucccu gucucag gaaccucagcggg augau gagaagggcug aa augcugccaaac cagguccuuuu cugau ggug gcuggggc uugguuaggg


>SELV_cavPor Cavia porcellus (guinea_pig) COVE score: 34.34
>SELV_cavPor Cavia porcellus (guinea_pig) score: 34.34
uuuucucccc auguuag gagcugcagcagg augau gagaagggcug aa auguuguugagu cagguccuuuu cugau ggugg cugggcu gaguggagcu
uuuucucccc auguuag gagcugcagcagg augau gagaagggcug aa auguuguugagu cagguccuuuu cugau ggugg cugggcu gaguggagcu


>SELV_equCab Equus caballus (horse) COVE score: 32.67
>SELV_equCab Equus caballus (horse) score: 32.67
uucucucucc aucucag gagccucggugag augac gagaagggcug aa auguugccaagu cagguccuuuu cugau ggcg gcugggg cugagguggg
uucucucucc aucucag gagccucggugag augac gagaagggcug aa auguugccaagu cagguccuuuu cugau ggcg gcugggg cugagguggg


>SELV_sorAra Sorex araneus (shrew) COVE score: 26.16  
>SELV_sorAra Sorex araneus (shrew) score: 26.16  
cuucucuccc caucuca ggaaccucagaag augaa gggaagggcug aa auguugg cagguccuuuu cugac agu ggcugug gcuaugaugg
cuucucuccc caucuca ggaaccucagaag augaa gggaagggcug aa auguugg cagguccuuuu cugac agu ggcugug gcuaugaugg


>SELV_loxAfr Loxodonta africana (elephant) COVE score: 34.00
>SELV_loxAfr Loxodonta africana (elephant) score: 34.00
uucucucccc aucucag gagccucagcaag augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cugggguggg
uucucucccc aucucag gagccucagcaag augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cugggguggg


>SELV_echTel Echinops telfairi (tenrec) COVE score: 26.31
>SELV_echTel Echinops telfairi (tenrec) score: 26.31
uucucucucc accccag gagccgcagcaag augac gagaagggcug aa augucgu caggcccuuuu cugag ggug gcugggg cuaggcucgg
uucucucucc accccag gagccgcagcaag augac gagaagggcug aa augucgu caggcccuuuu cugag ggug gcugggg cuaggcucgg
</pre>
</pre>
Line 1,230: Line 1,226:
=== SELH: 18 SECIS insertion sequences ===
=== SELH: 18 SECIS insertion sequences ===
<pre>
<pre>
>SELH_homSap Homo sapiens (human) COVE score: 23.94
>SELH_homSap Homo sapiens (human) score: 23.94
UUUGUGUCCC UGGUGAU GUUGGAACAUUA AUGAU GGAACAUGGCC AA ACUUC AGUCAUGAUCC UGAA GCC AUGGUU UCUUCCCUGC
UUUGUGUCCC UGGUGAU GUUGGAACAUUA AUGAU GGAACAUGGCC AA ACUUC AGUCAUGAUCC UGAA GCC AUGGUU UCUUCCCUGC


>SELH_panTro Pan troglodytes (chimp) COVE score: 23.94  
>SELH_panTro Pan troglodytes (chimp) score: 23.94  
uuuguguccc uggugau guuggaacauua augau ggaacauggcc aa acuuc agucaugaucc ugaa gcc augguu ucuucccugc
uuuguguccc uggugau guuggaacauua augau ggaacauggcc aa acuuc agucaugaucc ugaa gcc augguu ucuucccugc


>SELH_macMul Macaca mulatta (rhesus) COVE score: 26.97  
>SELH_macMul Macaca mulatta (rhesus) score: 26.97  
cuuugugucc cugguga ugcuggaacauua augau ggaacauggcc aa acuuc agucaugugcc ugaa gccaugg uuucua ccccgccaga
cuuugugucc cugguga ugcuggaacauua augau ggaacauggcc aa acuuc agucaugugcc ugaa gccaugg uuucua ccccgccaga


>SELH_otoGar Otolemur garnettii (bushbaby) COVE score: 22.59  
>SELH_otoGar Otolemur garnettii (bushbaby) score: 22.59  
cuuucugugc uggugau guuggagcaugu augac gggacauggcc aa acuua agucaugugcc ugaa gcu acaguuu cuuccccucc
cuuucugugc uggugau guuggagcaugu augac gggacauggcc aa acuua agucaugugcc ugaa gcu acaguuu cuuccccucc


>SELH_tupBel Tupaia belangeri (tree_shrew) COVE score: 26.55  
>SELH_tupBel Tupaia belangeri (tree_shrew) score: 26.55  
gcuuuuccug gugaugu ugaagggacauuu augau gggacauggcc aa acuuc agucaugugcc ugaa gcc aagguuu cuuccccucc
gcuuuuccug gugaugu ugaagggacauuu augau gggacauggcc aa acuuc agucaugugcc ugaa gcc aagguuu cuuccccucc


>SELH_musMus Mus musculus (mouse) COVE score: 24.55  
>SELH_musMus Mus musculus (mouse) score: 24.55  
cuuucagucc cuggaga uguugaagcauuu augau ggugcauggcc aa acuua agcuaugcacc ugaa gccauag uuucuu ccucaccaga
cuuucagucc cuggaga uguugaagcauuu augau ggugcauggcc aa acuua agcuaugcacc ugaa gccauag uuucuu ccucaccaga


>SELH_ratNor Rattus norvegicus (rat) COVE score: 23.97
>SELH_ratNor Rattus norvegicus (rat) score: 23.97
cuuucagucc cuggaga uguugaagcauuu augau ggugcauggcc aa acuua agcuauguacc ugaa gccauag uuucuu ccucaccaga
cuuucagucc cuggaga uguugaagcauuu augau ggugcauggcc aa acuua agcuauguacc ugaa gccauag uuucuu ccucaccaga


>SELH_cavPor Cavia porcellus (guinea_pig) COVE score: 19.25  
>SELH_cavPor Cavia porcellus (guinea_pig) score: 19.25  
uuucuguucc ugguccu guuggggcgucu gugau gggacauggc ca aacuaaag ccauggccc ugaa gcc augguc ucuagcaucc
uuucuguucc ugguccu guuggggcgucu gugau gggacauggc ca aacuaaag ccauggccc ugaa gcc augguc ucuagcaucc


>SELH_canFam Canis familiaris (dog) COVE score: 23.64  
>SELH_canFam Canis familiaris (dog) score: 23.64  
agcauauccc uggugau guuggagcauuu augac ggaacauggcc aa acuuc agucauguacc ugaa gcc augguu ucuucccucc
agcauauccc uggugau guuggagcauuu augac ggaacauggcc aa acuuc agucauguacc ugaa gcc augguu ucuucccucc


>SELH_felCat Felis catus (cat) COVE score: 24.80  
>SELH_felCat Felis catus (cat) score: 24.80  
cuucucuccc uggugac guuuggagcauuu augac gggacauggcc aa auuuc agucaugugcc ugaa gcccug guuucu uccccuccag
cuucucuccc uggugac guuuggagcauuu augac gggacauggcc aa auuuc agucaugugcc ugaa gcccug guuucu uccccuccag


>SELH_equCab Equus caballus (horse) COVE score: 25.73
>SELH_equCab Equus caballus (horse) score: 25.73
ccuucguccc ugguguu guuggagcauuu augac gguacauggcc aa acauc agucaugugcc ugaa gcu gugguuu cuuccccucc
ccuucguccc ugguguu guuggagcauuu augac gguacauggcc aa acauc agucaugugcc ugaa gcu gugguuu cuuccccucc


>SELH_bosTau Bos taurus (cow) COVE score: 28.39
>SELH_bosTau Bos taurus (cow) score: 28.39
ccucuguccc uggugau guuggagcauuu augac gggacauggcc aa acuuc agucauguccc ugaa gcu gugguu uccuccccuc
ccucuguccc uggugau guuggagcauuu augac gggacauggcc aa acuuc agucauguccc ugaa gcu gugguu uccuccccuc


>SELH_sorAra Sorex araneus (shrew) COVE score: 24.10
>SELH_sorAra Sorex araneus (shrew) score: 24.10
cuuucuguuc uggugau guuggagcauug augau ggaacaugacc aa acguc agucaugugcc ugaa gccaa guuucu uucucuccag
cuuucuguuc uggugau guuggagcauug augau ggaacaugacc aa acguc agucaugugcc ugaa gccaa guuucu uucucuccag


>SELH_dasNov Dasypus novemcinctus (armadillo) COVE score: 25.97
>SELH_dasNov Dasypus novemcinctus (armadillo) score: 25.97
cuucuauccu uggugau guuggagcauuu augau gggacauggcc aa acuuc agucauguacc ugaa gcca guuucu cccccuccag
cuucuauccu uggugau guuggagcauuu augau gggacauggcc aa acuuc agucauguacc ugaa gcca guuucu cccccuccag


>SELH_loxAfr Loxodonta africana (elephant) COVE score: 25.83  
>SELH_loxAfr Loxodonta africana (elephant) score: 25.83  
cuucuguccc uggugau guuggagcauuu augac ggaacauggcc aa accuc agucaugugcc ugaa gcc acgguuu cuuccccucc
cuucuguccc uggugau guuggagcauuu augac ggaacauggcc aa accuc agucaugugcc ugaa gcc acgguuu cuuccccucc


>SELH_echTel Echinops telfairi (tenrec) COVE score: 26.97
>SELH_echTel Echinops telfairi (tenrec) score: 26.97
agucccgucc cugguga uguuggagcauuu augau ggaacauggcc aa acuuc agucaugugcc ugaa gcccguc uccuca cuuccagaaa
agucccgucc cugguga uguuggagcauuu augau ggaacauggcc aa acuuc agucaugugcc ugaa gcccguc uccuca cuuccagaaa


>SELH_monDom Monodelphis domestica (opossum) COVE score: 26.74  
>SELH_monDom Monodelphis domestica (opossum) score: 26.74  
ugccuguccc cagugag uuuggagcaucc augau ggaaccugacc aa aucuccca gucacguccc ugaa gcuuggg cuccuu cuccugggaa
ugccuguccc cagugag uuuggagcaucc augau ggaaccugacc aa aucuccca gucacguccc ugaa gcuuggg cuccuu cuccugggaa


>SELH_anoCar Anolis carolinensis (lizard) COVE score: 27.10  
>SELH_anoCar Anolis carolinensis (lizard) score: 27.10  
auacauucuc ugugagu uggagcauuc augau gggauaugauc aa guggagcaaaucc agucacaucuc ugaa gcu guugcc cuccuccaca
auacauucuc ugugagu uggagcauuc augau gggauaugauc aa guggagcaaaucc agucacaucuc ugaa gcu guugcc cuccuccaca
</pre>
</pre>
Line 1,287: Line 1,283:
=== SEPP2: 5 SECIS sequences ===
=== SEPP2: 5 SECIS sequences ===
<pre>
<pre>
>SEPP2_SECIS_monDom Monodelphis domestica (opossum) chr2:9455773-9456962 COVE: 30 55 bp after stop codon
>SEPP2_SECIS_monDom Monodelphis domestica (opossum) chr2:9455773-9456962 score: 30 55 bp after stop codon
ACGUGCCGCU GCCCCUC CCUCCCUCCAAGA AUGAC GCCCACAGUGA AA CCCAGAGAACUGG UCCCUGUGGGC UGAU GCCC CAGAGGG GAGGAGAGGC
ACGUGCCGCU GCCCCUC CCUCCCUCCAAGA AUGAC GCCCACAGUGA AA CCCAGAGAACUGG UCCCUGUGGGC UGAU GCCC CAGAGGG GAGGAGAGGC


>SEPP2_SECIS_macEug Macropus eugenii (wallaby) SECIS COVE score: 26.38 trace ti|975557399 contains terminal exon
>SEPP2_SECIS_macEug Macropus eugenii (wallaby) SECIS score: 26.38 trace ti|975557399 contains terminal exon
CUUGCCCAUU GCCCUUC CCUCCCUCAAUUA AUGAU GCCCACAGUGA AA CCCGGGGAACCGG CCAUGGUGGGC UGAU GCCAU GGAGAAG AGGAAUGAGG
CUUGCCCAUU GCCCUUC CCUCCCUCAAUUA AUGAU GCCCACAGUGA AA CCCGGGGAACCGG CCAUGGUGGGC UGAU GCCAU GGAGAAG AGGAAUGAGG


>SEPP2a_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE: 34.28
>SEPP2a_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 34.28
UCCCUCGACU CCCGCUC CCGCCUCGCACUC AUGAC GUCCACGGUGUC AA CCGGCCCGCCG GGCACCGUGGAC UGAC GCC GGUCGAG GCGGAGGGGU
UCCCUCGACU CCCGCUC CCGCCUCGCACUC AUGAC GUCCACGGUGUC AA CCGGCCCGCCG GGCACCGUGGAC UGAC GCC GGUCGAG GCGGAGGGGU


>SEPP2b_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE: 22.82
>SEPP2b_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 22.82
GGAAUCAGGA ACCCAGU AAC AUGAG GUCAUCUUCGG AA GCCUGUGCCUAGAGGA CCAAGAUAAU GGAA AAAGUGACGG ACAAGGGU GUGUAGCUGG
GGAAUCAGGA ACCCAGU AAC AUGAG GUCAUCUUCGG AA GCCUGUGCCUAGAGGA CCAAGAUAAU GGAA AAAGUGACGG ACAAGGGU GUGUAGCUGG


>SEPP2_SECIS_tetNig Tetraodon nigroviridis (pufferfish) COVE: 17
>SEPP2_SECIS_tetNig Tetraodon nigroviridis (pufferfish) score: 17
GCUGGACCCA GGCUGCU GGUGGUCCCGUUG AUGAC GUCUGCGCUGGU AA ACCUGCCUGCAGG AGCCUGUGGAC CGAC GUG UGUGGAC CCACCGGCAG
GCUGGACCCA GGCUGCU GGUGGUCCCGUUG AUGAC GUCUGCGCUGGU AA ACCUGCCUGCAGG AGCCUGUGGAC CGAC GUG UGUGGAC CCACCGGCAG
</pre>
</pre>
Line 1,306: Line 1,302:


<pre>
<pre>
>SELI_SECIS_homSap Homo sapiens (human) COVE score: 21.61
>SELI_SECIS_homSap Homo sapiens (human) score: 21.61
UUUCACUGAA UGAAGUU UGUGCUUGA AUGAA GAGUGUAUCUUA AA CCCCCUUUUUUUGGA CAGGCUGCACUU GGAU AAAAUA GGCACCA CUGUGUUGAU
UUUCACUGAA UGAAGUU UGUGCUUGA AUGAA GAGUGUAUCUUA AA CCCCCUUUUUUUGGA CAGGCUGCACUU GGAU AAAAUA GGCACCA CUGUGUUGAU


>SELI_SECIS_panTro Pan troglodytes (chimp) COVE score: 21.61
>SELI_SECIS_panTro Pan troglodytes (chimp) score: 21.61
uuucacugaa ugaaguu ugugcuuga augaa gaguguaucuua aa cccccuuuuuuugga caggcugcacuu ggau aaaaua ggcacca cuguguugau
uuucacugaa ugaaguu ugugcuuga augaa gaguguaucuua aa cccccuuuuuuugga caggcugcacuu ggau aaaaua ggcacca cuguguugau


>SELI_SECIS_macMul Macaca mulatta (rhesus) COVE score: 21.25
>SELI_SECIS_macMul Macaca mulatta (rhesus) score: 21.25
uuucacugaa ugaaguu ugugcuuga augaa gaguguaucuua aa ccuccuuuuuuugga caggcugcacuu ggau aacaua ggcacca cuguguugau
uuucacugaa ugaaguu ugugcuuga augaa gaguguaucuua aa ccuccuuuuuuugga caggcugcacuu ggau aacaua ggcacca cuguguugau


>SELI_SECIS_otoGar Otolemur garnettii (bushbaby) COVE score: 21.25
>SELI_SECIS_otoGar Otolemur garnettii (bushbaby) score: 21.25
uuucacuaag ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuuuuuuggac agguugcacuu ggau aaaaua ggcacca uuguguugau
uuucacuaag ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuuuuuuggac agguugcacuu ggau aaaaua ggcacca uuguguugau


>SELI_SECIS_musMus Mus musculus (mouse) COVE score: 24.62
>SELI_SECIS_musMus Mus musculus (mouse) score: 24.62
uuccacugaa ugaaguu ugugcuuaa augaa gagugugucuu aa acccuuuuuuuuggac agguugcacuu ggau aaaaua ggcacca cuguguugau
uuccacugaa ugaaguu ugugcuuaa augaa gagugugucuu aa acccuuuuuuuuggac agguugcacuu ggau aaaaua ggcacca cuguguugau


>SELI_SECIS_ratNor Rattus norvegicus (rat) COVE score: 24.62
>SELI_SECIS_ratNor Rattus norvegicus (rat) score: 24.62
uuccacugaa ugaaguu ugugcuuaa augaa gagugugucuu aa acccuuuuuuuuggac agguugcacuu ggau aacaua ggcaccg cuguguugau
uuccacugaa ugaaguu ugugcuuaa augaa gagugugucuu aa acccuuuuuuuuggac agguugcacuu ggau aacaua ggcaccg cuguguugau


>SELI_SECIS_cavPor Cavia porcellus (guinea_pig) COVE score: 17.42
>SELI_SECIS_cavPor Cavia porcellus (guinea_pig) score: 17.42
uuccagugaa ugaaguu ugugcuuga augaa gaguguaucuua aa cccuuuuuuuuuugga cagguugcacuu ggau aaaaua ggcacca cuguguugau
uuccagugaa ugaaguu ugugcuuga augaa gaguguaucuua aa cccuuuuuuuuuugga cagguugcacuu ggau aaaaua ggcacca cuguguugau


>SELI_SECIS_oryCun Oryctolagus cuniculus (rabbit) COVE score: 19.47
>SELI_SECIS_oryCun Oryctolagus cuniculus (rabbit) score: 19.47
ucuacugaau gaaguuu gugcuuga augaa gaguguaucuua aa cccuuuuuuuuugga cagguugcacuu ggau aaaau aggcac cacuguugau
ucuacugaau gaaguuu gugcuuga augaa gaguguaucuua aa cccuuuuuuuuugga cagguugcacuu ggau aaaau aggcac cacuguugau


>SELI_SECIS_sorAra Sorex araneus (shrew) COVE score: COVE score: 8.13 loose
>SELI_SECIS_sorAra Sorex araneus (shrew) score: score: 8.13
uuccacugaa ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuauuuuguuuuuuugga cggauuacacuu ggau auaaua ggcacca uucuguugau
uuccacugaa ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuauuuuguuuuuuugga cggauuacacuu ggau auaaua ggcacca uucuguugau


>SELI_SECIS_eriEur Erinaceus europaeus (hedgehog) COVE score: 14.43 loose
>SELI_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 14.43
cacggaauga aguaugu gcuuga augaa gaguguaucuu aa acccuuuuuuuuuuuugga cagguugcacuu ggau aua auaggc accacucugu
cacggaauga aguaugu gcuuga augaa gaguguaucuu aa acccuuuuuuuuuuuugga cagguugcacuu ggau aua auaggc accacucugu


>SELI_SECIS_canFam Canis familiaris (dog) COVE score: 14.04
>SELI_SECIS_canFam Canis familiaris (dog) score: 14.04
uuccacugaa ugaaguu ugugcucga augaa gaguguaucuua aa cccuuuuuuuuuugga uggauugcacuu ggau aaaaua ggcacca cuguguugau
uuccacugaa ugaaguu ugugcucga augaa gaguguaucuua aa cccuuuuuuuuuugga uggauugcacuu ggau aaaaua ggcacca cuguguugau


>SELI_SECIS_equCab Equus caballus (horse) COVE score: 19.57
>SELI_SECIS_equCab Equus caballus (horse) score: 19.57
uuucacugag ugaaguu ugugcucga augaa gaguguauucuu aa acccuuguuuuugga uggauugcacuu ggau aaaaua agcacca cuguguugau
uuucacugag ugaaguu ugugcucga augaa gaguguauucuu aa acccuuguuuuugga uggauugcacuu ggau aaaaua agcacca cuguguugau


>SELI_SECIS_dasNov Dasypus novemcinctus (armadillo) COVE score: 17.76 loose
>SELI_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 17.76
cuacugaauu aaguuug ugcuuga augaa gaguguaucuu aa acccuuuguuuuuuugga cagguugcacuu ggau aaaa uaggca ccacuauguu
cuacugaauu aaguuug ugcuuga augaa gaguguaucuu aa acccuuuguuuuuuugga cagguugcacuu ggau aaaa uaggca ccacuauguu


>SELI_SECIS_loxAfr Loxodonta africana (elephant) COVE score: 25.81
>SELI_SECIS_loxAfr Loxodonta africana (elephant) score: 25.81
uuccacugaa ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuuuuuuggac agguugcacuu ggau aaagua ggcacca cuguguugau
uuccacugaa ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuuuuuuggac agguugcacuu ggau aaagua ggcacca cuguguugau


>SELI_SECIS_monDom Monodelphis domestica (opossum) COVE score: 26.46
>SELI_SECIS_monDom Monodelphis domestica (opossum) score: 26.46
uucuacugaa ugcaauu ugugcuuga augaa gagugugucuu aa auccuuuauauggac aggcugcacuu ggag aga auaagca caaccauguu
uucuacugaa ugcaauu ugugcuuga augaa gagugugucuu aa auccuuuauauggac aggcugcacuu ggag aga auaagca caaccauguu


>SELI_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE score: 19.25
>SELI_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 19.25
ucccagugaa ugaagcu ugugcuuga augaa gagugcaucuua aa cccauuuuuuuugga aaagcugcacuu ggag agaaag ggcacg acuguguuua
ucccagugaa ugaagcu ugugcuuga augaa gagugcaucuua aa cccauuuuuuuugga aaagcugcacuu ggag agaaag ggcacg acuguguuua


>SELI_SECIS_anoCar Anolis carolinensis (lizard) COVE score: 22.02
>SELI_SECIS_anoCar Anolis carolinensis (lizard) score: 22.02
uccccuuugu guguguc cuuugugcgugu augaa gagugcggccuc aa cccaggcgucuugga agggccgcaccc ggaa gaa acggagc acagcaaaga
uccccuuugu guguguc cuuugugcgugu augaa gagugcggccuc aa cccaggcgucuugga agggccgcaccc ggaa gaa acggagc acagcaaaga


>SELI_SECIS_galGal Gallus gallus (chicken) COVE score: 24.62
>SELI_SECIS_galGal Gallus gallus (chicken) score: 24.62
uuuuauugag uuuauuu gugcuuaa augaa gagugcgcuuc aa acccagaccaggag agggcgcacuu ggag ugagc gagucaa accuugcucc
uuuuauugag uuuauuu gugcuuaa augaa gagugcgcuuc aa acccagaccaggag agggcgcacuu ggag ugagc gagucaa accuugcucc
</pre>
</pre>
Line 1,363: Line 1,359:
=== SELK: 19 SECIS sequences ===
=== SELK: 19 SECIS sequences ===
<pre>
<pre>
>SELK_SECIS_homSap Homo sapiens (human) COVE score: 34.53
>SELK_SECIS_homSap Homo sapiens (human) score: 34.53
acaaggacug cucugug uccucacagauga augag gucaugcuggg aa uucccucugcaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu
acaaggacug cucugug uccucacagauga augag gucaugcuggg aa uucccucugcaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu


>SELK_SECIS_panTro Pan troglodytes (chimp) COVE score: 34.53  
>SELK_SECIS_panTro Pan troglodytes (chimp) score: 34.53  
acaaggacug cucugug uccucacagauga augag gucaugcuggg aa uucccucugcaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu
acaaggacug cucugug uccucacagauga augag gucaugcuggg aa uucccucugcaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu


>SELK_SECIS_macMul Macaca mulatta (rhesus) COVE score: 36.14  
>SELK_SECIS_macMul Macaca mulatta (rhesus) score: 36.14  
acaaggacug cucugug uccucacagauga augag gucaugcuagg aa uucccucuacaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu
acaaggacug cucugug uccucacagauga augag gucaugcuagg aa uucccucuacaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu


>SELK_SECIS_otoGar Otolemur garnettii (bushbaby) COVE score: 31.99
>SELK_SECIS_otoGar Otolemur garnettii (bushbaby) score: 31.99
caaggauugc ucugugu cuucacagauga augag gucaggcuggg aa uucucucuucaggga acuggccugac ugac augcagu ucuauaa acgcacuuuu
caaggauugc ucugugu cuucacagauga augag gucaggcuggg aa uucucucuucaggga acuggccugac ugac augcagu ucuauaa acgcacuuuu
 
>SELK_SECIS_tupBel Tupaia belangeri (tree_shrew) COVE score: 36.65
>SELK_SECIS_tupBel Tupaia belangeri (tree_shrew) score: 36.65
acaaggauug cucugug uccccacagauga augag guuaugccggg aa uucccuccacaggga ucuggccugac ugau acgcaguuc uauaaa ugcacauguu
acaaggauug cucugug uccccacagauga augag guuaugccggg aa uucccuccacaggga ucuggccugac ugau acgcaguuc uauaaa ugcacauguu


>SELK_SECIS_musMus Mus musculus (mouse) COVE score: 31.73
>SELK_SECIS_musMus Mus musculus (mouse) score: 31.73
acaaggauug cucugug uccccacagauga augag gucaugcuggg aa uucccucugcagga ucuagccugac ugau acgcaguuc uauaaa uguacauguu
acaaggauug cucugug uccccacagauga augag gucaugcuggg aa uucccucugcagga ucuagccugac ugau acgcaguuc uauaaa uguacauguu
 
>SELK_SECIS_ratNor Rattus norvegicus (rat) COVE score: 33.02
>SELK_SECIS_ratNor Rattus norvegicus (rat) score: 33.02
acaaggacug cucugug uccucacagaaga augag gucaugcuggg aa cucccucugcagga ucuggccugac ugau gugcaguuc uauaaa uguacaugug
acaaggacug cucugug uccucacagaaga augag gucaugcuggg aa cucccucugcagga ucuggccugac ugau gugcaguuc uauaaa uguacaugug
 
>SELK_SECIS_cavPor Cavia porcellus (guinea_pig) COVE score: 33.72
>SELK_SECIS_cavPor Cavia porcellus (guinea_pig) score: 33.72
cucuguguuc ucacaga uaa augag gucacgccagg aa uucucucagcaggga ucuggcuugac ugau acgcagu ucucua aaugcauaug
cucuguguuc ucacaga uaa augag gucacgccagg aa uucucucagcaggga ucuggcuugac ugau acgcagu ucucua aaugcauaug
 
>SELK_SECIS_oryCun Oryctolagus cuniculus (rabbit) COVE score: 38.80  
>SELK_SECIS_oryCun Oryctolagus cuniculus (rabbit) score: 38.80  
accaggauug cucugug uccccacagauga augau gucaggcuggg aa uucccuccacaggga ucuggccugau ugag augcaguuc uauaaa ugcguauguu
accaggauug cucugug uccccacagauga augau gucaggcuggg aa uucccuccacaggga ucuggccugau ugag augcaguuc uauaaa ugcguauguu


>SELK_SECIS_sorAra Sorex araneus (shrew) COVE score: 40.91
>SELK_SECIS_sorAra Sorex araneus (shrew) score: 40.91
auaaggacug uucugug uccacacagauga augag gucaugcuggg aa uucccucuacgggga ucuggcaugac ugau augcag uucgaua aaugcacaug
auaaggacug uucugug uccacacagauga augag gucaugcuggg aa uucccucuacgggga ucuggcaugac ugau augcag uucgaua aaugcacaug


>SELK_SECIS_eriEur Erinaceus europaeus (hedgehog) COVE score: 37.30
>SELK_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 37.30
acaaggauug cucugug uucucacagguga augag guuaugcuggg aa uucccuccaugggga ucuggcaugac ugau augcaguuc uauaaa ugcacauguu
acaaggauug cucugug uucucacagguga augag guuaugcuggg aa uucccuccaugggga ucuggcaugac ugau augcaguuc uauaaa ugcacauguu


>SELK_SECIS_canFam Canis familiaris (dog) COVE score: 36.30  
>SELK_SECIS_canFam Canis familiaris (dog) score: 36.30  
acaaggauug cucugug ccuucacagacgg augag guugugcuagg aa uucccuccccaggga ucuggcaugac ugac augcaguuc uauaaa ugcacauguu
acaaggauug cucugug ccuucacagacgg augag guugugcuagg aa uucccuccccaggga ucuggcaugac ugac augcaguuc uauaaa ugcacauguu


>SELK_SECIS_felCat Felis catus (cat) COVE score: 37.35
>SELK_SECIS_felCat Felis catus (cat) score: 37.35
acgagaauug cucugug uccucacagacag augag gucgugcuggg aa uucccuccccaggga ucuggcaugac ugac augcaguuc uauaaa ugcacauguu
acgagaauug cucugug uccucacagacag augag gucgugcuggg aa uucccuccccaggga ucuggcaugac ugac augcaguuc uauaaa ugcacauguu


>SELK_SECIS_bosTau Bos taurus (cow) COVE score: 39.16  
>SELK_SECIS_bosTau Bos taurus (cow) score: 39.16  
cucugugucc ucacaga cga augag gucaugcuggg aa uucccuccgcaggga ucuggcaugac ugac augcagu ucuaua aaugcacguu
cucugugucc ucacaga cga augag gucaugcuggg aa uucccuccgcaggga ucuggcaugac ugac augcagu ucuaua aaugcacguu


>SELK_SECIS_dasNov Dasypus novemcinctus (armadillo) COVE score: 29.00
>SELK_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 29.00
acaaggauug cucugug uccucacagauga augag gucauguuuggg aa uucccucugcaggg aucuggcaugac ugac uugcaguuc cauaaa ugcacauguu
acaaggauug cucugug uccucacagauga augag gucauguuuggg aa uucccucugcaggg aucuggcaugac ugac uugcaguuc cauaaa ugcacauguu


>SELK_SECIS_loxAfr Loxodonta africana (elephant) COVE score: 34.85  
>SELK_SECIS_loxAfr Loxodonta africana (elephant) score: 34.85  
acaaagacug cucugug uccccacagacgg augag gcugugcuggg aa uucccucugcaggga ucuggcauggc ugac augcaguuc cauaaa ugcacauguu
acaaagacug cucugug uccccacagacgg augag gcugugcuggg aa uucccucugcaggga ucuggcauggc ugac augcaguuc cauaaa ugcacauguu


>SELK_SECIS_monDom Monodelphis domestica (opossum) COVE score: 21.75
>SELK_SECIS_monDom Monodelphis domestica (opossum) score: 21.75
aagaauugcu cugucua cacagauua augau guugugcuggg aa cucccaucuuacagga uccaguguaac ugau ugcaa uuguaua aaugcacaug
aagaauugcu cugucua cacagauua augau guugugcuggg aa cucccaucuuacagga uccaguguaac ugau ugcaa uuguaua aaugcacaug


>SELK_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE score: 33.68
>SELK_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 33.68
aauaauugug cugugaa caagcagauua augau guuuugcuggg aa uuccuucaggga uccaguauaac ugau aaagc aauuaua uaaaggcaca
aauaauugug cugugaa caagcagauua augau guuuugcuggg aa uuccuucaggga uccaguauaac ugau aaagc aauuaua uaaaggcaca


>SELK_SECIS_anoCar Anolis carolinensis (lizard) COVE score: 33.87
>SELK_SECIS_anoCar Anolis carolinensis (lizard) score: 33.87
aauucccugc ucugcca auuggcgggacc augau guuguccuggg aa uuccuuauucuggga uccagggcaac ugaa aagcaguuc uguuaa auuaaaugca
aauucccugc ucugcca auuggcgggacc augau guuguccuggg aa uuccuuauucuggga uccagggcaac ugaa aagcaguuc uguuaa auuaaaugca


>SELK_SECIS_galGal Gallus gallus (chicken) COVE score: 30.90
>SELK_SECIS_galGal Gallus gallus (chicken) score: 30.90
ugagaacugu ucugcaa uauaagcagauga augaa guuguacuggg aa cuccuucaagga uccaguguaac ugaa gugcagug uuauuaa auacauguuu
ugagaacugu ucugcaa uauaagcagauga augaa guuguacuggg aa cuccuucaagga uccaguguaac ugaa gugcagug uuauuaa auacauguuu
</pre>
</pre>
Line 1,426: Line 1,422:
=== GPX3: 15 SECIS sequences ===
=== GPX3: 15 SECIS sequences ===
<pre>
<pre>
>GPX3_SECIS_homSap Homo sapiens (human) COVE score: 27.80
>GPX3_SECIS_homSap Homo sapiens (human) score: 27.80
CACGGACCCCA UGGCAGG GGUGGCGUCUUC AUGAG GGAGGGGCCCA AA GCCCUUGUGGGC GGACCUCCCC UGAG CCUG UCUGAG GGGCCAGCCCT
CACGGACCCCA UGGCAGG GGUGGCGUCUUC AUGAG GGAGGGGCCCA AA GCCCUUGUGGGC GGACCUCCCC UGAG CCUG UCUGAG GGGCCAGCCCT


>GPX3_SECIS_panTro Pan troglodytes (chimp) COVE score: 27.80
>GPX3_SECIS_panTro Pan troglodytes (chimp) score: 27.80  
cacguacccc augucgg ggguggugucuuc augag ggaggggccca aa gcccuugugggc ggaccucccc ugag ccugu cugagg ggccagcccu
cacguacccc augucgg ggguggugucuuc augag ggaggggccca aa gcccuugugggc ggaccucccc ugag ccugu cugagg ggccagcccu


>GPX3_SECIS_macMul Macaca mulatta (rhesus) COVE score: 27.80  
>GPX3_SECIS_macMul Macaca mulatta (rhesus) score: 27.80  
cacguacccc augucag ggguggcgucuuc augag ggaggggccca aa gcccuugugggc ggaccucccc ugag ccugu cugagg ggccagcucu
cacguacccc augucag ggguggcgucuuc augag ggaggggccca aa gcccuugugggc ggaccucccc ugag ccugu cugagg ggccagcucu


>GPX3_SECIS_tupBel Tupaia belangeri (tree_shrew) COVE score: 29.38  
>GPX3_SECIS_tupBel Tupaia belangeri (tree_shrew) score: 29.38  
ccacaucccu gugucag ggguggcaucucc augag ggaggggcccg aa gcccuuguggg cggaccucccc ugag ccugu cugagg ggccggcccu
ccacaucccu gugucag ggguggcaucucc augag ggaggggcccg aa gcccuuguggg cggaccucccc ugag ccugu cugagg ggccggcccu


>GPX3_SECIS_musMus Mus musculus (mouse) COVE score: 33.37  
>GPX3_SECIS_musMus Mus musculus (mouse) score: 33.37  
cguguacccc aggucag ggguggugucucu augaa ggaggggcccg aa gcccuuguggg cgggccucccc ugag cccgu cuguggu gccagcccuu
cguguacccc aggucag ggguggugucucu augaa ggaggggcccg aa gcccuuguggg cgggccucccc ugag cccgu cuguggu gccagcccuu
>GPX3_SECIS_ratNor Rattus norvegicus (rat) COVE score: 33.37
caugugcucc aagucag ggguggugucucc  augaa  ggaggggcccg  aa  gcccuuguggg cgggccucccc ugag cccgu cuguggu gccagcccuu
>GPX3_SECIS_canFam Canis familiaris (dog) COVE score: 29.96
cauguucccc gugucag gaauggcaucucc  augaa  ggaggggccc  ga  agcccucaugggc ggaccucccc ugag ccugu cugaag ggccggcccu


>GPX3_SECIS_felCat Felis catus (cat) COVE score: 30.08
>GPX3_SECIS_ratNor Rattus norvegicus (rat) score: 33.37
ccacguccc gugucag ggauggcgucucc  augaa ggaggggccc  ga  agcccuugugggc ggaccucccc ugag ccugu cugaag ggccagcccu
caugugcucc aagucag ggguggugucucc augaa ggaggggcccg aa gcccuuguggg cgggccucccc ugag cccgu cuguggu gccagcccuu


>GPX3_SECIS_equCab Equus caballus (horse) COVE score: 26.20
>GPX3_SECIS_canFam Canis familiaris (dog) score: 29.96
uacauucccc augucag ggguggcaucucc  augau  ggaggggcccg  aa  gcccugguggg cggaccucccc agag ccugu cugaag ggccagcccu
cauguucccc gugucag gaauggcaucucc augaa ggaggggccc ga agcccucaugggc ggaccucccc ugag ccugu cugaag ggccggcccu


>GPX3_SECIS_bosTau Bos taurus (cow) COVE score: 30.87
>GPX3_SECIS_felCat Felis catus (cat) score: 30.08
cacguuccccg ugucagg gggcggcaucgcc  augaa ggaggggcccg  aa  gcccgcguggg cgggccucccu ugag ccu gucugag gggccagccuu
ccacguccc gugucag ggauggcgucucc augaa ggaggggccc ga agcccuugugggc ggaccucccc ugag ccugu cugaag ggccagcccu


>GPX3_SECIS_loxAfr Loxodonta africana (elephant) COVE score: 16.32
>GPX3_SECIS_equCab Equus caballus (horse) score: 26.20
cuacgucccc gugucaa gagcggcaucucc  augau gguggggcccg  aa gccccugugg cggaccucccc agag ccugucc caugggc cagcccuu
uacauucccc augucag ggguggcaucucc augau ggaggggcccg aa gcccugguggg cggaccucccc agag ccugu cugaag ggccagcccu


>GPX3_SECIS_echTel Echinops telfairi (tenrec) COVE score: 12.78
>GPX3_SECIS_bosTau Bos taurus (cow) score: 30.87
ggcugugucc cgugcag agggagcaucucc  augag  ggugaggcccg  aa gcccccgugg cggaccucgac ccgag ucug cucugg gccugccuuc
cacguuccccg ugucagg gggcggcaucgcc augaa ggaggggcccg aa gcccgcguggg cgggccucccu ugag ccu gucugag gggccagccuu


>GPX3_SECIS_monDom Monodelphis domestica (opossum) COVE score: 22.94
>GPX3_SECIS_loxAfr Loxodonta africana (elephant) score: 16.32
ugaacauaag ggauggc aucucu  augau ggugggaucca  aa gccucuucaggg cggguuccauc agag ccugcaaaa gguguc aggacccuua
cuacgucccc gugucaa gagcggcaucucc augau gguggggcccg aa gccccugugg cggaccucccc agag ccugucc caugggc cagcccuu


>GPX3_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE score: 31.33
>GPX3_SECIS_echTel Echinops telfairi (tenrec) score: 12.78
ugucccagaa uggggag guggcaucauc  augac  agcggggucug  aa agccccuccugga uggaccccgcc cgaa ccug cucggcg guggcaugac
ggcugugucc cgugcag agggagcaucucc augag ggugaggcccg aa gcccccgugg cggaccucgac ccgag ucug cucugg gccugccuuc


>GPX3_SECIS_anoCar Anolis carolinensis (lizard) COVE score: 28.20
>GPX3_SECIS_monDom Monodelphis domestica (opossum) score: 22.94
GAGAUUUUGG GCCAAGG AAGUUGCAUCACU  AUGAG  GGUUAGGUCUG  AA  AGCUCCCAAAAAGAG CGGACCUAGCC UGAG GCUGCAAA GCUCUGGU GUAGCCCUUU
ugaacauaag ggauggc aucucu augau ggugggaucca aa gccucuucaggg cggguuccauc agag ccugcaaaa gguguc aggacccuua


>GPX3_SECIS_galGal Gallus gallus (chicken) COVE score: 30.65
>GPX3_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 31.33
GCCCUGGGGA GCAGAGG AUGACAUCUCC AUGAA GGCCUGGCCUG AA AGCCCCCACCAUGGGG UGGGCUCGGCC CGAU CCCG CCCAGGC GCGGUGCAGC  
ugucccagaa uggggag guggcaucauc augac agcggggucug aa agccccuccugga uggaccccgcc cgaa ccug cucggcg guggcaugac
 
>GPX3_SECIS_anoCar Anolis carolinensis (lizard) score: 28.20
GAGAUUUUGG GCCAAGG AAGUUGCAUCACU AUGAG GGUUAGGUCUG AA AGCUCCCAAAAAGAG CGGACCUAGCC UGAG GCUGCAAA GCUCUGGU GUAGCCCUUU
 
>GPX3_SECIS_galGal Gallus gallus (chicken) score: 30.65
GCCCUGGGGA GCAGAGG AUGACAUCUCC AUGAA GGCCUGGCCUG AA AGCCCCCACCAUGGGG UGGGCUCGGCC CGAU CCCG CCCAGGC GCGGUGCAGC  
</pre>
</pre>


=== GPX6: 10 SECIS sequences (most species have selenocysteine) ===
=== GPX6: 10 SECIS sequences (most species have selenocysteine) ===
<pre>
<pre>
>GPX6_SECIS_homSap Homo sapiens (human) chr6:28,578,901-28,580,158 Cove score: 18.10
>GPX6_SECIS_homSap Homo sapiens (human) chr6:28,578,901-28,580,158 score: 18.10
cccaccucac augaagg gaagggcaucucc augau gguggauccc aa aaccccucuggguc gcacccugcc agag ccu uccuug gugccugucc
cccaccucac augaagg gaagggcaucucc augau gguggauccc aa aaccccucuggguc gcacccugcc agag ccu uccuug gugccugucc
>GPX6_SECIS_panTro Pan troglodytes (chimp) COVE score: 23.45
cccaccucac augaagg gaggggcaucucc  augac  gguggguccc  aa  aaccucucgggguc ggacccugcc agag ccu uccuug gugccugucc
>GPX6_SECIS_macMul Macaca mulatta (rhesus) COVE score: 21.81
accucauuca cagaagg gaggggcaucuuu  augau  ggugggucuc  aa  aaccucucuggguc agacccuacc agag ccu uccuug gugccugucc


>GPX6_SECIS_cavPor Cavia porcellus (guinea_pig) AAKN02051715 Cove score: 19.91
>GPX6_SECIS_panTro Pan troglodytes (chimp) score: 23.45
AGAAGCCUCC CUAGAAG GAAGGGUGUCUCC  AUGAU  GGUGGGUCCC  AA  AAGCCCUGGAUC GGACCCUACC AGAA CCU UCCCUGG UGCCUGUCCU
cccaccucac augaagg gaggggcaucucc augac gguggguccc aa aaccucucgggguc ggacccugcc agag ccu uccuug gugccugucc


>GPX6_SECIS_canFam Canis familiaris (dog) Cove score: 24.33 but not found in 28way
>GPX6_SECIS_macMul Macaca mulatta (rhesus) score: 21.81
CCUGGCCUCA UAUGAAA GGAGGGCAUCUCC  AUGAU  GGUGGGUUCC  CA  AGCCCCUGCGGUC GGACCCUACC AGAG CCU UCUUGG GUGCCUGUCC
accucauuca cagaagg gaggggcaucuuu augau ggugggucuc aa aaccucucuggguc agacccuacc agag ccu uccuug gugccugucc


>GPX6_SECIS_equCab Equus caballus (horse) COVE score: 25.00
>GPX6_SECIS_cavPor Cavia porcellus (guinea_pig) AAKN02051715 score: 19.91
uucaucucac augagcu gaggggcaucucc  augau  gguggguccc  aa  agccccugugggc aggacccaac cagaa cucug ugccugu cccuuagugc
AGAAGCCUCC CUAGAAG GAAGGGUGUCUCC AUGAU GGUGGGUCCC AA AAGCCCUGGAUC GGACCCUACC AGAA CCU UCCCUGG UGCCUGUCCU
>GPX6_SECIS_bosTau Bos taurus (cow) COVE score: 23.33
cucacuucac augagga aaagggcaucucc  augau  gguggguccc  aa  agccucucuggguc ggaccccacc agag ccu uccuugg ugccuguccc
>GPX6_SECIS_eriEur Erinaceus europaeus (hedgehog) COVE score: 24.33
ccuggccuca uaugaaa ggagggcaucucc  augau  gguggguucc  ca  agccccugcgguc ggacccuacc agag ccu uccuugg ugucuguccu


>GPX6_SECIS_sorAra Sorex araneus (shrew) frag COVE score: 22.95
>GPX6_SECIS_canFam Canis familiaris (dog) score: 24.33 but not found in 28way
uuucauauga aaggagg gggcaucucc  augau  ggugggucuc  aa  agccccucuggguc ggacccuacc agag cccugcugg guguccu gucccuuugu
CCUGGCCUCA UAUGAAA GGAGGGCAUCUCC AUGAU GGUGGGUUCC CA AGCCCCUGCGGUC GGACCCUACC AGAG CCU UCUUGG GUGCCUGUCC


>GPX6_SECIS_dasNov Dasypus novemcinctus (armadillo) COVE score: 19.82
>GPX6_SECIS_equCab Equus caballus (horse) score: 25.00
cucaccuuac augaagg gagggacauaucc  augau gguggguccu  aa agcccuucuggguc agacccuacc agaa ccu ucucug gugccugucc
uucaucucac augagcu gaggggcaucucc augau gguggguccc aa agccccugugggc aggacccaac cagaa cucug ugccugu cccuuagugc


>GPX6_SECIS_loxAfr Loxodonta africana (elephant) COVE score: 19.28  
>GPX6_SECIS_bosTau Bos taurus (cow) score: 23.33
cucaccucac augaaug gaggggcauaucc augau gguggguccc aa agccucucuagguc ggacccuauc agaa ucuucccugg ugccugu cccuuagugc
cucacuucac augagga aaagggcaucucc augau gguggguccc aa agccucucuggguc ggaccccacc agag ccu uccuugg ugccuguccc
 
>GPX6_SECIS_echTel Echinops telfairi (tenrec) frag COVE score: 31.33  
>GPX6_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 24.33
ugugucccag aaugggg agguggcaucauc augac agcggggucu ga aagccccuccuggau ggaccccgcc cgaa ccu ucccug gugccugucc
ccuggccuca uaugaaa ggagggcaucucc augau gguggguucc ca agccccugcgguc ggacccuacc agag ccu uccuugg ugucuguccu
 
>GPX6_SECIS_sorAra Sorex araneus (shrew) frag score: 22.95
uuucauauga aaggagg gggcaucucc augau ggugggucuc aa agccccucuggguc ggacccuacc agag cccugcugg guguccu gucccuuugu
 
>GPX6_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 19.82
cucaccuuac augaagg gagggacauaucc augau gguggguccu aa agcccuucuggguc agacccuacc agaa ccu ucucug gugccugucc
 
>GPX6_SECIS_loxAfr Loxodonta africana (elephant) score: 19.28  
cucaccucac augaaug gaggggcauaucc augau gguggguccc aa agccucucuagguc ggacccuauc agaa ucuucccugg ugccugu cccuuagugc
 
>GPX6_SECIS_echTel Echinops telfairi (tenrec) frag score: 31.33  
ugugucccag aaugggg agguggcaucauc augac agcggggucu ga aagccccuccuggau ggaccccgcc cgaa ccu ucccug gugccugucc
</pre>
</pre>


=== GPX1: 17 SECIS insertion sequences ===
=== GPX1: 17 SECIS insertion sequences ===
<pre>
<pre>
>GPX1_homSap Homo sapiens (human) COVE score: 20.45
>GPX1_homSap Homo sapiens (human) score: 20.45
UGCUGUCUCG GGGGGGU UUUCAUCU AUGAG GGUGUUUCCUCU AA ACCUACGA GGGAGGAACACC UGAU CUUACAGAAA AUACCAC CUCGAGAUGG
UGCUGUCUCG GGGGGGU UUUCAUCU AUGAG GGUGUUUCCUCU AA ACCUACGA GGGAGGAACACC UGAU CUUACAGAAA AUACCAC CUCGAGAUGG


>GPX1_panTro Pan troglodytes (chimp) COVE score: 20.45  
>GPX1_panTro Pan troglodytes (chimp) score: 20.45  
gugcugcucu guggggg gguuuucaucu augag gguguuuccucu aa accuacga gggaggaacacc ugau cuuacagaaa auacccc cucgagaugg
gugcugcucu guggggg gguuuucaucu augag gguguuuccucu aa accuacga gggaggaacacc ugau cuuacagaaa auacccc cucgagaugg


>GPX1_macMul Macaca mulatta (rhesus) COVE score: 26.45  
>GPX1_macMul Macaca mulatta (rhesus) score: 26.45  
gcagcgcugc ucucugg gggguuuucaucu augag gguguuuccucu aa accuaca aggaggaacacc ugau aau acagaa aauacccccu
gcagcgcugc ucucugg gggguuuucaucu augag gguguuuccucu aa accuaca aggaggaacacc ugau aau acagaa aauacccccu


>GPX1_otoGar Otolemur garnettii (bushbaby) COVE score: 25.30  
>GPX1_otoGar Otolemur garnettii (bushbaby) score: 25.30  
auagcgcugc ucucugg ggggguuucauuc augau aguguuaccucu aa acuugcau gggggaacacc ugau gcc ccagaaa auccccugag
auagcgcugc ucucugg ggggguuucauuc augau aguguuaccucu aa acuugcau gggggaacacc ugau gcc ccagaaa auccccugag


>GPX1_tupBel Tupaia belangeri (tree_shrew) COVE score: 21.14
>GPX1_tupBel Tupaia belangeri (tree_shrew) score: 21.14
cagcgcugcg ucugggg gguuucaucc augac ggugucuccucu aa accccga aggaggaacgcc ugau guccggaaaa cccccca ggugggcgcc
cagcgcugcg ucugggg gguuucaucc augac ggugucuccucu aa accccga aggaggaacgcc ugau guccggaaaa cccccca ggugggcgcc


>GPX1_musMus Mus musculus (mouse) COVE score: 29.78  
>GPX1_musMus Mus musculus (mouse) score: 29.78  
ggcugcacuc ugggggg cgguucuucc augau gguguuuccucu aa auuugca cggagaaacacc ugau uuccaggaa aaucccc ucagaugggc
ggcugcacuc ugggggg cgguucuucc augau gguguuuccucu aa auuugca cggagaaacacc ugau uuccaggaa aaucccc ucagaugggc


>GPX1_ratNor Rattus norvegicus (rat) COVE score: 25.72
>GPX1_ratNor Rattus norvegicus (rat) score: 25.72
ggcugcccuc cgggggg agguuuuucc augac gguguuuccucu aa auuuaca uggagaaacacc ugau uuccagaaa aaucccc ucagaugggc
ggcugcccuc cgggggg agguuuuucc augac gguguuuccucu aa auuuaca uggagaaacacc ugau uuccagaaa aaucccc ucagaugggc


>GPX1_cavPor Cavia porcellus (guinea_pig) COVE score: 15.34  
>GPX1_cavPor Cavia porcellus (guinea_pig) score: 15.34  
uugcccagau gcucucc ugaggguucuucc augaa gguguuuccucuc aa ccugua uagaggaacauc cgau uccca ggaauu ucccagagag
uugcccagau gcucucc ugaggguucuucc augaa gguguuuccucuc aa ccugua uagaggaacauc cgau uccca ggaauu ucccagagag


>GPX1_oryCun Oryctolagus cuniculus (rabbit) COVE score: 24.38  
>GPX1_oryCun Oryctolagus cuniculus (rabbit) score: 24.38  
guggccugcu gcucucu ggggguuucaucc augag ggcguucccccg aa aacaaa uggaggaacgcc ugau gucc gggaaac ccccaggugg
guggccugcu gcucucu ggggguuucaucc augag ggcguucccccg aa aacaaa uggaggaacgcc ugau gucc gggaaac ccccaggugg


>GPX1_eriEur Erinaceus europaeus (hedgehog) COVE score: 19.31  
>GPX1_eriEur Erinaceus europaeus (hedgehog) score: 19.31  
auagccgcga gccgcug ggcaucucaucc augac ggcgccgccuuc aa accugcgagcag gaaggagcgcc cgau agc cgcgaga gcccccagcg
auagccgcga gccgcug ggcaucucaucc augac ggcgccgccuuc aa accugcgagcag gaaggagcgcc cgau agc cgcgaga gcccccagcg


>GPX1_canFam Canis familiaris (dog) COVE score: 22.40  
>GPX1_canFam Canis familiaris (dog) score: 22.40  
ucacagcgcu gcccucu ggggauuucaucc augau gguguuuccuug aa aucugca uggaggaacgcc ugau uucca ggaaagu ccccugagcu
ucacagcgcu gcccucu ggggauuucaucc augau gguguuuccuug aa aucugca uggaggaacgcc ugau uucca ggaaagu ccccugagcu


>GPX1_felCat Felis catus (cat) COVE score: 27.75  
>GPX1_felCat Felis catus (cat) score: 27.75  
cacagcacug cccucug gggauuucaucc augau ggcguuuccucg aa auuugca uagaggaacgcc ugau uuc cagaag aauccccuga
cacagcacug cccucug gggauuucaucc augau ggcguuuccucg aa auuugca uagaggaacgcc ugau uuc cagaag aauccccuga


>GPX1_equCab Equus caballus (horse) COVE score: 27.08
>GPX1_equCab Equus caballus (horse) score: 27.08
ucacagugcu uuucucu ggggauuucaucc augau ggcguuuccucu aa acaugc augaggaacgcc ugau guu aaggaga aucccccgag
ucacagugcu uuucucu ggggauuucaucc augau ggcguuuccucu aa acaugc augaggaacgcc ugau guu aaggaga aucccccgag


>GPX1_bosTau Bos taurus (cow) COVE score: 29.83  
>GPX1_bosTau Bos taurus (cow) score: 29.83  
agucagcgcu gcucucc agggauuuugccc augaa gguguucccucu aa accuacg uggaggaaugcc ugau gucca ggaaaau ccccugaggu
agucagcgcu gcucucc agggauuuugccc augaa gguguucccucu aa accuacg uggaggaaugcc ugau gucca ggaaaau ccccugaggu


>GPX1_dasNov Dasypus novemcinctus (armadillo) COVE score: 28.92
>GPX1_dasNov Dasypus novemcinctus (armadillo) score: 28.92
uguccuccac acggggu uuucaucc augac gguguuuccucu aa accugca gggaggaacacc ugaa guccggcaaa aucccc cgagaugggu
uguccuccac acggggu uuucaucc augac gguguuuccucu aa accugca gggaggaacacc ugaa guccggcaaa aucccc cgagaugggu


>GPX1_loxAfr Loxodonta africana (elephant) COVE score: 25.48  
>GPX1_loxAfr Loxodonta africana (elephant) score: 25.48  
acuaggcggc uuuccgu ggggguuucauua augag gguguuuucucu aa accugaa uggaggaacacc ugau guc ugggaa gauacccccc
acuaggcggc uuuccgu ggggguuucauua augag gguguuuucucu aa accugaa uggaggaacacc ugau guc ugggaa gauacccccc


>GPX1_monDom Monodelphis domestica (opossum) COVE score: 26.38  
>GPX1_monDom Monodelphis domestica (opossum) score: 26.38  
gugcuaaggg uccguga ggguuuuaucu augau gguguuguuuu aa accauuaagga gaaagaacacu ugau aaugc uuguaa aaucccauga
gugcuaaggg uccguga ggguuuuaucu augau gguguuguuuu aa accauuaagga gaaagaacacu ugau aaugc uuguaa aaucccauga


>GPX1_ornAna Ornithorhynchus anatinus (platypus) COVE score: 25.55
>GPX1_ornAna Ornithorhynchus anatinus (platypus) score: 25.55
ugcuauuugc ccauggg ggagaucucauuu augau ggugcuccuucu aa accuuua cggaagagcacu ugau gga uccugag gaacuccaug
ugcuauuugc ccauggg ggagaucucauuu augau ggugcuccuucu aa accuuua cggaagagcacu ugau gga uccugag gaacuccaug
</pre>
</pre>


=== GPX2: 17 SECIS insertion sequences ===
=== GPX2: 17 SECIS insertion sequences ===
<pre>
<pre>
>GPX2_homSap Homo sapiens (human) COVE score: 29.54  
>GPX2_homSap Homo sapiens (human) score: 29.54  
AGACUUGGGU AAGCUCU GGGCCUUCACAGA AUGAU GGCACCUUCCU AA ACCCUCA UGGGUGGUGUC UGAG AGGCGUGA AGGGCCU GGAGCCACUC
AGACUUGGGU AAGCUCU GGGCCUUCACAGA AUGAU GGCACCUUCCU AA ACCCUCA UGGGUGGUGUC UGAG AGGCGUGA AGGGCCU GGAGCCACUC


>GPX2_panTro Pan troglodytes (chimp) COVE score: 29.54  
>GPX2_panTro Pan troglodytes (chimp) score: 29.54  
agacuugggu aagcucu gggccuucacaga augau ggcaccuuccu aa acccuca ugggugguguc ugag aggcguga agggccu ggagccacuc
agacuugggu aagcucu gggccuucacaga augau ggcaccuuccu aa acccuca ugggugguguc ugag aggcguga agggccu ggagccacuc


>GPX2_macMul Macaca mulatta (rhesus) COVE score: 29.54
>GPX2_macMul Macaca mulatta (rhesus) score: 29.54
agacuugggu aagcucu gggccuucacaga augau ggcaccuuccu aa acccuca ugggugguguc ugag aggcguga agggccu gaagccaccc
agacuugggu aagcucu gggccuucacaga augau ggcaccuuccu aa acccuca ugggugguguc ugag aggcguga agggccu gaagccaccc


>GPX2_otoGar Otolemur garnettii (bushbaby) COVE score: 27.86
>GPX2_otoGar Otolemur garnettii (bushbaby) score: 27.86  
agacuugggu gggcucu gggccuucacaga augau ggcaccauccu aa acgccuc ugggugguguc ugag aagagcg gaaggcc uggagccacc
agacuugggu gggcucu gggccuucacaga augau ggcaccauccu aa acgccuc ugggugguguc ugag aagagcg gaaggcc uggagccacc


>GPX2_tupBel Tupaia belangeri (tree_shrew) COVE score: 28.69  
>GPX2_tupBel Tupaia belangeri (tree_shrew) score: 28.69  
agacuuaggu gggcucu gagccuucacaga augau agcaccuuccu aa acccccc cgggagguguc ugag aagugug acaggcc cggagccagc
agacuuaggu gggcucu gagccuucacaga augau agcaccuuccu aa acccccc cgggagguguc ugag aagugug acaggcc cggagccagc


>GPX2_musMus Mus musculus (mouse) COVE score: 33.65  
>GPX2_musMus Mus musculus (mouse) score: 33.65  
agucuggggu agguucu gggccuucacaga augau ggcaucuuccu aa acccuuc ugggagauguc ugag aaguugug aaggguc cagagccagu
agucuggggu agguucu gggccuucacaga augau ggcaucuuccu aa acccuuc ugggagauguc ugag aaguugug aaggguc cagagccagu


>GPX2_ratNor Rattus norvegicus (rat) COVE score: 30.80  
>GPX2_ratNor Rattus norvegicus (rat) score: 30.80  
cugggguagg ugcuagg ccuucuucacaga augau ggcaucuuccu aa acccuuc ugggggauguc ugag acg uugugaa gggcccagag
cugggguagg ugcuagg ccuucuucacaga augau ggcaucuuccu aa acccuuc ugggggauguc ugag acg uugugaa gggcccagag


>GPX2_cavPor Cavia porcellus (guinea_pig) COVE score: 20.08
>GPX2_cavPor Cavia porcellus (guinea_pig) score: 20.08  
cuaggacagg uggcucu gggccuucacaga augac ggcaccguccu aa acgcua ugggugguauc ugag aagugug aauggcug gagccagccu
cuaggacagg uggcucu gggccuucacaga augac ggcaccguccu aa acgcua ugggugguauc ugag aagugug aauggcug gagccagccu


>GPX2_sorAra Sorex araneus (shrew) COVE score: 29.00  
>GPX2_sorAra Sorex araneus (shrew) score: 29.00  
aagcuggggc aaacucu gggccuucgcaga augau ggcaccucccu aa auccau ggggugguguc ugag gcgugcg agggccu ggaaacagcc
aagcuggggc aaacucu gggccuucgcaga augau ggcaccucccu aa auccau ggggugguguc ugag gcgugcg agggccu ggaaacagcc


>GPX2_eriEur Erinaceus europaeus (hedgehog) COVE score: 25.06  
>GPX2_eriEur Erinaceus europaeus (hedgehog) score: 25.06  
aaagcugggu gguuucu ggaccuucacaga augau agcaccuuccu aa accuaua gggaugguguc ugag aaaugu gaagggc cugaaguaaa
aaagcugggu gguuucu ggaccuucacaga augau agcaccuuccu aa accuaua gggaugguguc ugag aaaugu gaagggc cugaaguaaa


>GPX2_canFam Canis familiaris (dog) COVE score: 22.57
>GPX2_canFam Canis familiaris (dog) score: 22.57  
aagacuuggg uggcucu gggccuucacaga augau ggcaccuuccu aa auagua ugggcgguguc ugag aagugug aagggcu cagagccagc
aagacuuggg uggcucu gggccuucacaga augau ggcaccuuccu aa auagua ugggcgguguc ugag aagugug aagggcu cagagccagc


>GPX2_felCat Felis catus (cat) COVE score: 22.45  
>GPX2_felCat Felis catus (cat) score: 22.45  
aagacuuggg uggaucu gggccuucacaga augau ggcaucuuccu aa acugua ugggcgguguc ugag gaguguga agggcu cggagccagc
aagacuuggg uggaucu gggccuucacaga augau ggcaucuuccu aa acugua ugggcgguguc ugag gaguguga agggcu cggagccagc


>GPX2_equCab Equus caballus (horse) COVE score: 28.45
>GPX2_equCab Equus caballus (horse) score: 28.45
agacuucggu aggcucu gggccuucacaga augau ggcaccuuccu aa accugua uggacgguguc ugaa aagcgug aagggcc ccgagucagc
agacuucggu aggcucu gggccuucacaga augau ggcaccuuccu aa accugua uggacgguguc ugaa aagcgug aagggcc ccgagucagc


>GPX2_bosTau Bos taurus (cow) COVE score: 26.14
>GPX2_bosTau Bos taurus (cow) score: 26.14
agacaugggu gggcucu gugucuucacaga augau ggcaccuuccu aa aucugua ugggcgguguu ugag aagagu gaaggcc uggagccagc
agacaugggu gggcucu gugucuucacaga augau ggcaccuuccu aa aucugua ugggcgguguu ugag aagagu gaaggcc uggagccagc


>GPX2_loxAfr Loxodonta africana (elephant) COVE score: 27.08
>GPX2_loxAfr Loxodonta africana (elephant) score: 27.08  
agacuugggu aggcucu ggaccuucgcaga augau ggcaccuuccu aa acucag ugggugguguc ugag aaaugug aagggccu agggccagcc
agacuugggu aggcucu ggaccuucgcaga augau ggcaccuuccu aa acucag ugggugguguc ugag aaaugug aagggccu agggccagcc


>GPX2_echTel Echinops telfairi (tenrec) COVE score: 29.95  
>GPX2_echTel Echinops telfairi (tenrec) score: 29.95  
agugcuggug uggcucu gggccuucacaga augau ggcaccuuccu aa acccuc cggaagguguc ugag aaaugug aagggcc uggggccggc
agugcuggug uggcucu gggccuucacaga augau ggcaccuuccu aa acccuc cggaagguguc ugag aaaugug aagggcc uggggccggc


>GPX2_monDom Monodelphis domestica (opossum) COVE score: 26.38  
>GPX2_monDom Monodelphis domestica (opossum) score: 26.38  
gugcuaaggg uccguga ggguuuuaucu augau gguguuguuuu aa accauuaagga gaaagaacacu ugau aaugc uuguaa aaucccauga
gugcuaaggg uccguga ggguuuuaucu augau gguguuguuuu aa accauuaagga gaaagaacacu ugau aaugc uuguaa aaucccauga


>GPX2_ornAna Ornithorhynchus anatinus (platypus) COVE score: 27.55
>GPX2_ornAna Ornithorhynchus anatinus (platypus) score: 27.55
gggcucgagc agccucc agaccuucacaga augac ggugucuccuu aa acccuaac cgggaggcacc cgag agccggu gaagggc cuggugacug
gggcucgagc agccucc agaccuucacaga augac ggugucuccuu aa acccuaac cgggaggcacc cgag agccggu gaagggc cuggugacug
</pre>
</pre>


=== GPX4: 14 SECIS sequences ===
=== GPX4: 14 SECIS sequences ===
<PRE>
<PRE>
>GPX4_SECIS_homSap Homo sapiens (human) chr19:1,057,512-1,057,793 COVE score: 29.19
>GPX4_SECIS_homSap Homo sapiens (human) chr19:1,057,512-1,057,793 score: 29.19
CCACGCCCUU GGAGCCU UCCACCGGCACUC AUGAC GGCCUGCCUG CA AACCUGCUGGU GGGGCAGACC CGAA AAUCC AGCGUGC ACCCCGCCGG
CCACGCCCUU GGAGCCU UCCACCGGCACUC AUGAC GGCCUGCCUG CA AACCUGCUGGU GGGGCAGACC CGAA AAUCC AGCGUGC ACCCCGCCGG


>GPX4_SECIS_panTro Pan troglodytes (chimp) COVE score: 29.19
>GPX4_SECIS_panTro Pan troglodytes (chimp) score: 29.19
CCACGCCCUC GGAGCCU UCCACCAGCACCC AUGAc ggccugccug ca aaccugcuggu ggggcagacc cgaa aaucc agcgugc acccugccgg
CCACGCCCUC GGAGCCU UCCACCAGCACCC AUGAc ggccugccug ca aaccugcuggu ggggcagacc cgaa aaucc agcgugc acccugccgg


>GPX4_SECIS_macMul Macaca mulatta (rhesus) COVE score: 33.09
>GPX4_SECIS_macMul Macaca mulatta (rhesus) score: 33.09
CCACGCCCUC GGAGCCU UCCACCGGCACCC AUGAc ggccugcuugc aa accagcuccuggu gaggcagacc cgaa aaucc agcgugc accccgcugg
CCACGCCCUC GGAGCCU UCCACCGGCACCC AUGAc ggccugcuugc aa accagcuccuggu gaggcagacc cgaa aaucc agcgugc accccgcugg


>GPX4_SECIS_tupBel Tupaia belangeri (tree_shrew) COVE score: 31.05  
>GPX4_SECIS_tupBel Tupaia belangeri (tree_shrew) score: 31.05  
CCGCGCCCCG GAACCUU CCACCCGGCACCU UUGAc ggucugccuau aa accugccacug gugaggcagacc cgag aaccu ggcgugc acccugccgg
CCGCGCCCCG GAACCUU CCACCCGGCACCU UUGAc ggucugccuau aa accugccacug gugaggcagacc cgag aaccu ggcgugc acccugccgg


>GPX4_SECIS_musMus Mus musculus (mouse) COVE score: 35.62  
>GPX4_SECIS_musMus Mus musculus (mouse) score: 35.62  
UGACCCCUGG AGCCUUC CACCCCGGCACUC AUGAa ggucugccug aa aaccagccugcuggu ggggcagucc ugag gaccu ggcgugc acccugccgg
UGACCCCUGG AGCCUUC CACCCCGGCACUC AUGAa ggucugccug aa aaccagccugcuggu ggggcagucc ugag gaccu ggcgugc acccugccgg


>GPX4_SECIS_ratNor Rattus norvegicus (rat) COVE score: 34.33
>GPX4_SECIS_ratNor Rattus norvegicus (rat) score: 34.33
UGACCCCUGG AGCCUUC CACCCCGGCACUC AUGAc ggucugccug aa aaccagcccgcuggu ggggcagucc cgag gaccu ggcgugc accccgccgg
UGACCCCUGG AGCCUUC CACCCCGGCACUC AUGAc ggucugccug aa aaccagcccgcuggu ggggcagucc cgag gaccu ggcgugc accccgccgg


>GPX4_SECIS_cavPor Cavia porcellus (guinea_pig) COVE score: 34.46  
>GPX4_SECIS_cavPor Cavia porcellus (guinea_pig) score: 34.46  
UGGCCGCCCC GAGUCUC CUACCCGGGUGCC AUGAc ggccugccug ca aaccagcgug cugguggggc agac ccg aggaugc gugcacugcc
UGGCCGCCCC GAGUCUC CUACCCGGGUGCC AUGAc ggccugccug ca aaccagcgug cugguggggc agac ccg aggaugc gugcacugcc


>GPX4_SECIS_canFam Canis familiaris (dog) COVE score: 31.12  
>GPX4_SECIS_canFam Canis familiaris (dog) score: 31.12  
AUGCCCCUCG GAGCCUU CCACCCGGCACCC AUGAc agucugucuaa aa accagcccgcugg uggggcagacc cgag aaccc ggcgugc acccugccgg
AUGCCCCUCG GAGCCUU CCACCCGGCACCC AUGAc agucugucuaa aa accagcccgcugg uggggcagacc cgag aaccc ggcgugc acccugccgg


>GPX4_SECIS_sorAra Sorex araneus (shrew) COVE score: 36.85  
>GPX4_SECIS_sorAra Sorex araneus (shrew) score: 36.85  
CUGCCCCUCG GAGCCUU CCACCCGGCGCCC AUGAc ggucugccugc aa accagccc gcugguggggc agac ccgagaaccc ggcgugc accuugccgg
CUGCCCCUCG GAGCCUU CCACCCGGCGCCC AUGAc ggucugccugc aa accagccc gcugguggggc agac ccgagaaccc ggcgugc accuugccgg


>GPX4_SECIS_bosTau Bos taurus (cow) COVE score: ?
>GPX4_SECIS_bosTau Bos taurus (cow) score: ?
tgttccgagaAGCCTTCCCCCGGtgCctATGACGGTCTGtCTGAAAACCAGCCCCTGGTGGGGCAGaCCtGAGaACCTGGCGTGCACtccttccgg
tgttccgagaAGCCTTCCCCCGGtgCctATGACGGTCTGtCTGAAAACCAGCCCCTGGTGGGGCAGaCCtGAGaACCTGGCGTGCACtccttccgg


>GPX4_SECIS_echTel Echinops telfairi (tenrec) COVE score: 40.88
>GPX4_SECIS_echTel Echinops telfairi (tenrec) score: 40.88
UUGAUCCCCA GAGUCUU CCACCCGGCACCA AUGAc ggucugccuuc aa accaggccucugg ugaggcagacc cgau gaccc ggcgugc acucagccgg
UUGAUCCCCA GAGUCUU CCACCCGGCACCA AUGAc ggucugccuuc aa accaggccucugg ugaggcagacc cgau gaccc ggcgugc acucagccgg


>GPX4_SECIS_monDom Monodelphis domestica (opossum) COVE score: 40.88  
>GPX4_SECIS_monDom Monodelphis domestica (opossum) score: 40.88  
UUGAUCCCCA GAGUCUU CCACCCGGCACCA AUGAC GGUCUGCCUUC AA ACCAGGCCUCUGG UGAGGCAGACC CGAU GACCC GGCGUGC ACCUCAGCCG
UUGAUCCCCA GAGUCUU CCACCCGGCACCA AUGAC GGUCUGCCUUC AA ACCAGGCCUCUGG UGAGGCAGACC CGAU GACCC GGCGUGC ACCUCAGCCG


>GPX4_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE score: 33.89
>GPX4_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 33.89
ACCUCCGCUU UCCCGGG ACGCUCUGCCUCC AUGAc ggccggccuu ca agccaaaaccaguugg uggggccggcc ugaa caa accggca cgggucccgg
ACCUCCGCUU UCCCGGG ACGCUCUGCCUCC AUGAc ggccggccuu ca agccaaaaccaguugg uggggccggcc ugaa caa accggca cgggucccgg


>GPX4_SECIS_anoCar Anolis carolinensis (lizard) COVE score: 38.77
>GPX4_SECIS_anoCar Anolis carolinensis (lizard) score: 38.77
UGCUCCCCGU GGGCCCC CUCCUCCAGCACC AUGAc ggccugccuug aa gccagcuugcugg ugaggcagacc cgaa gauuc ggcgugc acugcuggag
UGCUCCCCGU GGGCCCC CUCCUCCAGCACC AUGAc ggccugccuug aa gccagcuugcugg ugaggcagacc cgaa gauuc ggcgugc acugcuggag


>GPX4_SECIS_galGal Gallus gallus (chicken) COVE score: 38.77
>GPX4_SECIS_galGal Gallus gallus (chicken) score: 38.77
UGCUCCCCGU GGGCCCC CUCCUCCAGCACC AUGAc ggccugccuug aa gccagcuugcugg ugaggcagacc cgaa gauuc ggcgugc acugcuggag
UGCUCCCCGU GGGCCCC CUCCUCCAGCACC AUGAc ggccugccuug aa gccagcuugcugg ugaggcagacc cgaa gauuc ggcgugc acugcuggag
</PRE>
</PRE>


=== SEPW: 13 SECIS sequences ===
=== SEPW: 13 SECIS sequences ===
<pre>
<pre>
>SEPW_SECIS_homSap Homo sapiens (human) COVE score: 36.01
>SEPW_SECIS_homSap Homo sapiens (human) score: 36.01
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG


>SEPW_SECIS_panTro Pan troglodytes (chimp) COVE score: 36.01
>SEPW_SECIS_panTro Pan troglodytes (chimp) score: 36.01
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUuGUGG CUGCUGUUGG
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUuGUGG CUGCUGUUGG


>SEPW_SECIS_ponPyg Pongo pygmaeus (orang_sumatran) COVE score: 30.55
>SEPW_SECIS_ponPyg Pongo pygmaeus (orang_sumatran) score: 30.55
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAAUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAAUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG


>SEPW_SECIS_macMul Macaca mulatta (rhesus) COVE score: 33.55
>SEPW_SECIS_macMul Macaca mulatta (rhesus) score: 33.55
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACgCC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACgCC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG


>SEPW_SECIS_musMus Mus musculus (mouse) COVE score: 34.04
>SEPW_SECIS_musMus Mus musculus (mouse) score: 34.04
UUGGCCCAGC CCCUCGU GGCAGACGCUUC AUGAU GGGAAGAACUG AA AUGUCUCGUGGACGC CUGGUCUUUCC CUGAU GUCCCU GCGACUG CCACGUAGGG
UUGGCCCAGC CCCUCGU GGCAGACGCUUC AUGAU GGGAAGAACUG AA AUGUCUCGUGGACGC CUGGUCUUUCC CUGAU GUCCCU GCGACUG CCACGUAGGG


>SEPW_SECIS_ ratNor Rattus norvegicus (rat) COVE score: 26.55
>SEPW_SECIS_ ratNor Rattus norvegicus (rat) score: 26.55
UGGCCGGCCU UUCUUGG CAGCCGCUUC AUGAC AGGAAGGACUG AA AUGUCUCAAAGACCUG UGGUCUUUCUU CGAU GUU CCUGCGG CCACCAAGUC
UGGCCGGCCU UUCUUGG CAGCCGCUUC AUGAC AGGAAGGACUG AA AUGUCUCAAAGACCUG UGGUCUUUCUU CGAU GUU CCUGCGG CCACCAAGUC


>SEPW_SECIS_canFam Canis familiaris (dog) COVE score: 34.04
>SEPW_SECIS_canFam Canis familiaris (dog) score: 34.04
UUGGCCCAGC CCCUCGU GGCAGACGCUUC AUGAU GGGAAGAACU GA AAUGUCUCGUGGACGCC UGGUCUUUCC CUGAU GUCCCU GCGACUG CCACGUAGGG
UUGGCCCAGC CCCUCGU GGCAGACGCUUC AUGAU GGGAAGAACU GA AAUGUCUCGUGGACGCC UGGUCUUUCC CUGAU GUCCCU GCGACUG CCACGUAGGG


Line 1,702: Line 1,698:
AGTAACCTTGACCCAGCCCCTTTCATGCCTCAGCCTCGTCTCCATAGGCTAAGACTGGAGAAGTCTTGTGGACGCCTGGTCTTTCCCTGATGTTCTCGTGGCTGCTGTTGGGGGCAGAGATGGATGAGCTGGTCTTTAC
AGTAACCTTGACCCAGCCCCTTTCATGCCTCAGCCTCGTCTCCATAGGCTAAGACTGGAGAAGTCTTGTGGACGCCTGGTCTTTCCCTGATGTTCTCGTGGCTGCTGTTGGGGGCAGAGATGGATGAGCTGGTCTTTAC


>SEPW_SECIS_borAnc Boreoeuthere ancestralis (ancestral) COVE score: 33.54
>SEPW_SECIS_borAnc Boreoeuthere ancestralis (ancestral) score: 33.54
GGCCCAGCCC CUCUCAG CAGAUGCUUC AUGAC AGGAAGGACUG AA AUGUCUUGUGGACGCC UGGUCUUUCCC UGAU GUU CUUGUGG CUGCUGGUUG
GGCCCAGCCC CUCUCAG CAGAUGCUUC AUGAC AGGAAGGACUG AA AUGUCUUGUGGACGCC UGGUCUUUCCC UGAU GUU CUUGUGG CUGCUGGUUG


>SEPW_SECIS_dasNov Dasypus novemcinctus (armadillo) COVE score: 28.71
>SEPW_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 28.71
CCCAGCUGCC CUUGGCA GACGCUUC AUGAG GGGAAGGACCU AA AUGCGUCGUGGAUGCC UGGUCUUUCCC UGAU GCUCCUUCAC CUGCCAG AUGGGGCAGA
CCCAGCUGCC CUUGGCA GACGCUUC AUGAG GGGAAGGACCU AA AUGCGUCGUGGAUGCC UGGUCUUUCCC UGAU GCUCCUUCAC CUGCCAG AUGGGGCAGA


Line 1,717: Line 1,713:
=== DIO1: 8 SECIS sequences ===
=== DIO1: 8 SECIS sequences ===
<pre>
<pre>
>DIO1_SECIS_homSap Homo sapiens (human) COVE score: 29.16
>DIO1_SECIS_homSap Homo sapiens (human) score: 29.16
uuuuaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag
uuuuaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag


>DIO1_SECIS_ponPyg Pongo pygmaeus (orang) COVE score: 29.16
>DIO1_SECIS_ponPyg Pongo pygmaeus (orang) score: 29.16
uuuuaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag
uuuuaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag


>DIO1_SECIS_macMul Macaca mulatta (rhesus) COVE score: 29.16
>DIO1_SECIS_macMul Macaca mulatta (rhesus) score: 29.16
uuucaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag
uuucaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag


>DIO1_SECIS_cavPor Cavia porcellus (guinea pig) COVE score: 23.71
>DIO1_SECIS_cavPor Cavia porcellus (guinea pig) score: 23.71
uguuaacucu gcuucuu uucauauuuguuc augac ggucacagucu aa aguacaca cagcugugacc ugau uuga aagaaa auguuuuaag
uguuaacucu gcuucuu uucauauuuguuc augac ggucacagucu aa aguacaca cagcugugacc ugau uuga aagaaa auguuuuaag


>DIO1_SECIS_bosTau Bos taurus (cow) COVE score: 27.83
>DIO1_SECIS_bosTau Bos taurus (cow) score: 27.83
uuuaacucug ccucuuu ucauauuuguuc augac ggccacagccu aa aguacaca cggcugugacu ugau uug aaagaa aauguuuuaa
uuuaacucug ccucuuu ucauauuuguuc augac ggccacagccu aa aguacaca cggcugugacu ugau uug aaagaa aauguuuuaa


>DIO1_SECIS_sorAra Sorex araneus (shrew) COVE score: 23.57
>DIO1_SECIS_sorAra Sorex araneus (shrew) score: 23.57
ggaaacucag cuucucu ucauauuuguuu augac agccccagcug aa aguacaca cagcuguggcu ugau ugg aaagaa aauguuuuaa
ggaaacucag cuucucu ucauauuuguuu augac agccccagcug aa aguacaca cagcuguggcu ugau ugg aaagaa aauguuuuaa


>DIO1_SECIS_eriEur Erinaceus europaeus (hedgehog) COVE score: 25.87
>DIO1_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 25.87
uuuaacucug cuuucuu cucauauuugcuu augau ggucacagcuu aa aguauaca cagcugugacu ugau ugg aaagaa aauauuuuaa
uuuaacucug cuuucuu cucauauuugcuu augau ggucacagcuu aa aguauaca cagcugugacu ugau ugg aaagaa aauauuuuaa


>DIO1_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE score: 23.83
>DIO1_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 23.83
cccggauccg guuccgu gaauauugguuu augag ggucacagugu aa agcgcaug cagcugugacu ugau cug agaaaau auuucugcgg
cccggauccg guuccgu gaauauugguuu augag ggucacagugu aa agcgcaug cagcugugacu ugau cug agaaaau auuucugcgg
</pre>
</pre>
Line 1,744: Line 1,740:
=== DIO2: 12 SECIS insertion sequences ===
=== DIO2: 12 SECIS insertion sequences ===
<pre>
<pre>
>DIO2_SECIS_homSap Homo sapiens (human) COVE score: 29.74
>DIO2_SECIS_homSap Homo sapiens (human) score: 29.74
cagagaugug cagaguu gaccagugugcgg augau aacuacugacg aa agagucaucgacuc aguuagugguu ggau guaguc acauuag uuugccucuc
cagagaugug cagaguu gaccagugugcgg augau aacuacugacg aa agagucaucgacuc aguuagugguu ggau guaguc acauuag uuugccucuc


>DIO2_SECIS_macMul Macaca mulatta (rhesus) COVE score: 29.74
>DIO2_SECIS_macMul Macaca mulatta (rhesus) score: 29.74
cagagaugug cagaguu gaccagugugcgg augau aacuacugacg aa agagucaucgacuc aguuagugguu ggau guaguc acauuag uuugccucuc
cagagaugug cagaguu gaccagugugcgg augau aacuacugacg aa agagucaucgacuc aguuagugguu ggau guaguc acauuag uuugccucuc


>DIO2_SECIS_musMus Mus musculus (mouse) COVE score: 29.14
>DIO2_SECIS_musMus Mus musculus (mouse) score: 29.14
cggagauguu cagagcu cacuggugugcga augau aacuacugacg aa agagcugucugcuc agucugugguu ggau guagucacac gagucug ccuuucugca
cggagauguu cagagcu cacuggugugcga augau aacuacugacg aa agagcugucugcuc agucugugguu ggau guagucacac gagucug ccuuucugca


>DIO2_SECIS_ratNor Rattus norvegicus (rat) COVE score: 27.88
>DIO2_SECIS_ratNor Rattus norvegicus (rat) score: 27.88
ccgagauguu cggagcu cacuggugugcga augau aacuacugacg aa agagucaucugcuc agucugugguu ggau guagucacac gagucug ccucuccauc
ccgagauguu cggagcu cacuggugugcga augau aacuacugacg aa agagucaucugcuc agucugugguu ggau guagucacac gagucug ccucuccauc


>DIO2_SECIS_canFam Canis familiaris (dog) COVE score: 27.29
>DIO2_SECIS_canFam Canis familiaris (dog) score: 27.29
cugggaugug cagaggu gaccagugugcga augau aacuacugaug aa agagucacugacuc aguuagugguu ggau aca gucacau uaguuuuccu
cugggaugug cagaggu gaccagugugcga augau aacuacugaug aa agagucacugacuc aguuagugguu ggau aca gucacau uaguuuuccu


>DIO2_SECIS_dasNov Dasypus novemcinctus (armadillo) COVE score: 26.93
>DIO2_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 26.93
cugggaaguu cagaggc uaccagugugcca augau aacuacugacg aa agaggcaucgacuc aguuagugguu ggau gua gccacau uaguuugccu
cugggaaguu cagaggc uaccagugugcca augau aacuacugacg aa agaggcaucgacuc aguuagugguu ggau gua gccacau uaguuugccu


>DIO2_SECIS_monDom Monodelphis domestica (opossum) COVE score: 28.86
>DIO2_SECIS_monDom Monodelphis domestica (opossum) score: 28.86
guguggaagg gcugcca gugugcaa augau gaucucuaaca aa agagucagucacuc cguuagagguu ggau gugg ucacagu ggcuugcugc
guguggaagg gcugcca gugugcaa augau gaucucuaaca aa agagucagucacuc cguuagagguu ggau gugg ucacagu ggcuugcugc


>DIO2_SECIS_ornAna Ornithorhynchus anatinus (platypus) COVE score: 24.54
>DIO2_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 24.54
ccaggauagg gcugagu uacuagugugcaa augaa gaccaccaaca aa agagaauuuaacuc aguuggugcuc agau auc aucacac uggcuuacuu
ccaggauagg gcugagu uacuagugugcaa augaa gaccaccaaca aa agagaauuuaacuc aguuggugcuc agau auc aucacac uggcuuacuu


>DIO2_SECIS_anoCar Anolis carolinensis (lizard) COVE score: 27.11
>DIO2_SECIS_anoCar Anolis carolinensis (lizard) score: 27.11
ugaggaugaa gcagagc uguuggugucuuu augaa gaucaccaaca aa agagugucucauuc aguugguguuc agau gucuua gcacug gcauuucucu
ugaggaugaa gcagagc uguuggugucuuu augaa gaucaccaaca aa agagugucucauuc aguugguguuc agau gucuua gcacug gcauuucucu


>DIO2_SECIS_galGal Gallus gallus (chicken) COVE score: 24.57
>DIO2_SECIS_galGal Gallus gallus (chicken) score: 24.57
ggggugaaac cugaaug cuuguguguuu augaa gagcacuaaca aa agaguaauugacuc aguugguguuc agau acucuca cacugg cauuccucug
ggggugaaac cugaaug cuuguguguuu augaa gagcacuaaca aa agaguaauugacuc aguugguguuc agau acucuca cacugg cauuccucug
</pre>
</pre>
Line 1,777: Line 1,773:
=== DIO3: 10 SECIS insertion sequences ===
=== DIO3: 10 SECIS insertion sequences ===
<pre>
<pre>
>DIO3_SECIS_homSap Homo sapiens (human) COVE score: 31
>DIO3_SECIS_homSap Homo sapiens (human) score: 31
uugggugcac aggagcc ccacugcug augac gaacuaucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaagcagca
uugggugcac aggagcc ccacugcug augac gaacuaucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaagcagca


>DIO3_ panTro Pan troglodytes (chimp) COVE score 30.95
>DIO3_ panTro Pan troglodytes (chimp) score 30.95
uugggugcac aggagcc ccacugcug augac gaacuaucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaagcagca
uugggugcac aggagcc ccacugcug augac gaacuaucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaagcagca


>DIO3_SECIS_macMul Macaca mulatta (rhesus) COVE score: 30  
>DIO3_SECIS_macMul Macaca mulatta (rhesus) score: 30  
uugggugcac aggagcc ccacugcug augac gaacugucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaaacagca
uugggugcac aggagcc ccacugcug augac gaacugucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaaacagca


>DIO3_SECIS_musMus Mus musculus (mouse) COVE score: 26
>DIO3_SECIS_musMus Mus musculus (mouse) score: 26  
gugcgcugga gcccugg cugcug augac gaaccgccucu aa cugggcuugaccac gggucggcuc ugaa uugca gagaggc ucgaaacagc
gugcgcugga gcccugg cugcug augac gaaccgccucu aa cugggcuugaccac gggucggcuc ugaa uugca gagaggc ucgaaacagc


>DIO3_SECIS_ratNor Rattus norvegicus (rat) COVE score: 26  
>DIO3_SECIS_ratNor Rattus norvegicus (rat) score: 26  
gugcgcugga gcccugg cugcug augac gaaccgccucu aa cugggcuugaccac gggucggcuc ugaa uugca gagaggc ucgaaacagc
gugcgcugga gcccugg cugcug augac gaaccgccucu aa cugggcuugaccac gggucggcuc ugaa uugca gagaggc ucgaaacagc


>DIO3_ cavPor Cavia porcellus (guinea pig) COVE score 24.06
>DIO3_ cavPor Cavia porcellus (guinea pig) score 24.06
uguuuugggc gcgcaug agccccucugcug augac gaacugucccu aa cuggucucgacc acgggcggguu ccgaa auug caggaug gcucgaaucg
uguuuugggc gcgcaug agccccucugcug augac gaacugucccu aa cuggucucgacc acgggcggguu ccgaa auug caggaug gcucgaaucg


>DIO3_ canFam Canis familiaris (dog) COVE score 25.84
>DIO3_ canFam Canis familiaris (dog) score 25.84
uauuuugggu gcuggcg agccccacugcug augac gagccgccucu aa cuggucuugacca cgagcugguuc ugag uugcagggg ggcuugc agcggcgccu
uauuuugggu gcuggcg agccccacugcug augac gagccgccucu aa cuggucuugacca cgagcugguuc ugag uugcagggg ggcuugc agcggcgccu


>DIO3_ felCat Felis catus (cat) COVE score 29.2
>DIO3_ felCat Felis catus (cat) score 29.2
cauuuggggu gcucacg agccccacugcug augac gagcuaucucu aa cuggucuugacca cgagcugguuc ugaa ccgc agggggc uugcagcagc
cauuuggggu gcucacg agccccacugcug augac gagcuaucucu aa cuggucuugacca cgagcugguuc ugaa ccgc agggggc uugcagcagc


>DIO3_ bosTau Bos taurus (cow) COVE score 23.46
>DIO3_ bosTau Bos taurus (cow) score 23.46
uauuuugggu gcucacg agccccacugcug augaa gagcugucucu aa cuggccucgacca cgagcugguuc ugau uugc aggaggc ucgcagcagc
uauuuugggu gcucacg agccccacugcug augaa gagcugucucu aa cuggccucgacca cgagcugguuc ugau uugc aggaggc ucgcagcagc


>DIO3_ loxAfr Loxodonta africana (elephant) COVE score 21.95
>DIO3_ loxAfr Loxodonta africana (elephant) score 21.95
uguuuucggu gcgcuag agccccacugcug augac gaacugucucu aa cuggucuugaccac gagcugauuc cgaa uugcagggaa cucgcagc agcgccuaaa
uguuuucggu gcgcuag agccccacugcug augac gaacugucucu aa cuggucuugaccac gagcugauuc cgaa uugcagggaa cucgcagc agcgccuaaa
</pre>
</pre>
Line 1,810: Line 1,806:
=== SELM2: 16 non-canonical SECIS insertion sequences ===
=== SELM2: 16 non-canonical SECIS insertion sequences ===
<pre>
<pre>
>SELM2_homSap Homo sapiens (human) COVE score: non-canonical  
>SELM2_homSap Homo sapiens (human) score: non-canonical  
ggggacgggcatcggctctcagcaagagaagtattcccgggatgctgagcgcttcattctgtctcc
ggggacgggcatcggctctcagcaagagaagtattcccgggatgctgagcgcttcattctgtctcc  


>SELM2_panTro Pan troglodytes (chimp) COVE score: non-canonical  
>SELM2_panTro Pan troglodytes (chimp) score: non-canonical  
ggggacgggcatcggctctcagcaagagaagtattcccgggatgctgagcgcttcattctgtctcc
ggggacgggcatcggctctcagcaagagaagtattcccgggatgctgagcgcttcattctgtctcc  


>SELM2_macMul Macaca mulatta (rhesus) COVE score: non-canonical  
>SELM2_macMul Macaca mulatta (rhesus) score: non-canonical  
ggggacggggcatcggccctcagcaagagaggtattcccgggatgctgagcgcttcattctgtctcc
ggggacggggcatcggccctcagcaagagaggtattcccgggatgctgagcgcttcattctgtctcc  


>SELM2_tupBel Tupaia belangeri (tree_shrew) COVE score: non-canonical  
>SELM2_tupBel Tupaia belangeri (tree_shrew) score: non-canonical  
ggggacagcacatcggcccccagcaagggaggtgctcccgggatgctgagcgcttcattcggtctcc
ggggacagcacatcggcccccagcaagggaggtgctcccgggatgctgagcgcttcattcggtctcc  


>SELM2_musMus Mus musculus (mouse) COVE score: non-canonical  
>SELM2_musMus Mus musculus (mouse) score: non-canonical  
ggagactggcgtcggccctcagcaagggagatgctcccgggatactgagcgcttcattctgtctcc
ggagactggcgtcggccctcagcaagggagatgctcccgggatactgagcgcttcattctgtctcc  


>SELM2_ratNor Rattus norvegicus (rat) COVE score: non-canonical  
>SELM2_ratNor Rattus norvegicus (rat) score: non-canonical  
ggagaccggcgtcggccctcagcaagagagtttatgctcccgggatgctgagcgcttcattctgtctcc
ggagaccggcgtcggccctcagcaagagagtttatgctcccgggatgctgagcgcttcattctgtctcc  


>SELM2_cavPor Cavia porcellus (guinea pig) COVE score: non-canonical  
>SELM2_cavPor Cavia porcellus (guinea pig) score: non-canonical  
agacgggcatcggtcctcagcaagggagatgctcccgggatgctgagcacttcattcggtcttc
agacgggcatcggtcctcagcaagggagatgctcccgggatgctgagcacttcattcggtcttc  


>SELM2_oryCun Oryctolagus cuniculus (rabbit) COVE score: non-canonical  
>SELM2_oryCun Oryctolagus cuniculus (rabbit) score: non-canonical  
ggggacggggcgtcggccctcagcaagggagggggctcccgggatgctgagcgcttcatcgtgtctccc
ggggacggggcgtcggccctcagcaagggagggggctcccgggatgctgagcgcttcatcgtgtctccc  


>SELM2_sorAra Sorex araneus (shrew) COVE score: non-canonical  
>SELM2_sorAra Sorex araneus (shrew) score: non-canonical  
ggggacggggcgtcgaccctcagcgagggagtgctcccgggacactgagggcttcattctgtcccc
ggggacggggcgtcgaccctcagcgagggagtgctcccgggacactgagggcttcattctgtcccc  


>SELM2_canFam Canis familiaris (dog) COVE score: non-canonical  
>SELM2_canFam Canis familiaris (dog) score: non-canonical  
tgggacgaggcatcggccctcagcgagggagacgctcccgggacgctgagcgcttcattctgtcccc
tgggacgaggcatcggccctcagcgagggagacgctcccgggacgctgagcgcttcattctgtcccc  


>SELM2_felCat Felis catus (cat) COVE score: non-canonical  
>SELM2_felCat Felis catus (cat) score: non-canonical  
tgggacggggcgtcggccctcagcgagggaggtgttcccgggacgctgagcgcttcattctgtcccc
tgggacggggcgtcggccctcagcgagggaggtgttcccgggacgctgagcgcttcattctgtcccc  


>SELM2_equCab Equus caballus (horse) COVE score: non-canonical  
>SELM2_equCab Equus caballus (horse) score: non-canonical  
cgggaccgagcgtcggccctcagcgagggaggtgctcccgggacgctgaacgcttcattctgtcccc
cgggaccgagcgtcggccctcagcgagggaggtgctcccgggacgctgaacgcttcattctgtcccc  


>SELM2_bosTau Bos taurus (cow) COVE score: non-canonical  
>SELM2_bosTau Bos taurus (cow) score: non-canonical  
ggggacggggcgtcggccctcaacgagggaggtgctcccgggccgctgagcgcttcattctgtcccc
ggggacggggcgtcggccctcaacgagggaggtgctcccgggccgctgagcgcttcattctgtcccc  


>SELM2_dasNov Dasypus novemcinctus (armadillo) COVE score: non-canonical  
>SELM2_dasNov Dasypus novemcinctus (armadillo) score: non-canonical  
taggacagggcgtcggccctcagcgagggagatgctcccgggccgctgagcgcttcattcggtcccc
taggacagggcgtcggccctcagcgagggagatgctcccgggccgctgagcgcttcattcggtcccc  


>SELM2_anoCar Anolis carolinensis (lizard) COVE score: non-canonical  
>SELM2_anoCar Anolis carolinensis (lizard) score: non-canonical  
agggacgctgtctatccaccctcggcggcaagagctttcgtccgagggcttcatcctgtcccg
agggacgctgtctatccaccctcggcggcaagagctttcgtccgagggcttcatcctgtcccg  
</pre>
</pre>


=== MSRB2: 0 SECIS insertion sequences (lack selenocysteine) ===
=== MSRB2: 0 SECIS insertion sequences (lack selenocysteine) ===
=== MSRB3: 0 SECIS insertion sequences (lack selenocysteine) ===
=== MSRB3: 0 SECIS insertion sequences (lack selenocysteine) ===
=== GPX5: 0 SECIS sequences (cysteine all species) ===
=== GPX5: 0 SECIS sequences (cysteine all species) ===
=== GPX7: 0 SECIS sequences (all species have cysteine) ===
=== GPX7: 0 SECIS sequences (all species have cysteine) ===
=== GPX8: 0 SECIS sequences (all species have cysteine or serine) ===
=== GPX8: 0 SECIS sequences (all species have cysteine or serine) ===
=== SELU1: 0 SECIS sequences (none in vertebrates) ===
=== SELU1: 0 SECIS sequences (none in vertebrates) ===
=== SELU2: 0 SECIS sequences (none in vertebrates) ===
=== SELU2: 0 SECIS sequences (none in vertebrates) ===
=== SELU3: 0 SECIS sequences (none in vertebrates) ===
=== SELU3: 0 SECIS sequences (none in vertebrates) ===
=== SEPHS1: 0 SECIS sequences (none in vertebrates) ===
=== SEPHS1: 0 SECIS sequences (none in vertebrates) ===


[[Category:Comparative Genomics]]
[[Category:Comparative Genomics]]

Revision as of 16:19, 10 June 2008

Introduction to selenocysteine insertion into selenoproteins

The SECIS element in 3' UTR of selenoproteins allows the insertion of selenocysteine for the appropriate TGA codon at time of translation. Auxillary gene products are needed for this to happen, including a selenocysteine-specific translation elongation factor (eEFSec), Sec-tRNA[Ser]Sec, ribosomal protein L30, and a binding protein (SBP2).

The SBP2 protein has three domains, including a conserved L7Ae RNA binding motif for SECIS RNA binding, a not completely overlapping ribosome binding site and a redox-sensitive cysteine-rich domain. SBP2 shuttles between the nucleus and the cytoplasm via nuclear localization motif SELEQNESSKKNKKKKEKSKSSYEVLPVQE and nuclear export signal motifs, the latter using the CRM1 pathway.


The kink-turn tertiary structure in the SECIS element is at the core of binding recognition. A mutation in that of SEPN or in SB2 lead to rigid spine muscular dystrophy or abnormal thyroid hormone function, the latter through inadequate production of DIO2 needed to activate thyroid hormone T4.

SecisKiaaKink.jpg

A strong paralog of BP2 was noticed and briely studied earlier. That protein, KIAA0256, also has 17 coding exons with near-identical intron locations and phases and full-length alignability, establishing KIAA0256 and BP2 as resulting from an ancestral gene duplication. The percent identity overall is only 42% but reaches 72% (human to human) in the 3 exons defining the L7Ae kink-turn binding motif.

Since both genes can be recovered from chondrichthyes, lamprey, and amphioxus, the duplication event preceded the emergence of chordates. The roots of the selenoproteome and the insertion mechanism lie much deeper in pre-metazoa so it follows that the parent gene must have assumed the key SECIS recognition roles (as did both descendent genes, at least initially).

We could ask if KIAA0256 still plays a role in SECIS in contemporary organisms. One possibility is that some of the 30-odd selenoproteins preferentially use KIAA0256 over BP2, correlating to the two observed structural classes of SECIS elements (which needs to be revisited in the genomics era). Another possibility is differential use during development or in various cell types. It's worth noting that KIAA0256 is considerably more conserved across its length than BP2, which has only a few exons conserved back to fish) suggesting the latter has a more limited role.

A literature review establishes that DIO, GPX, and SEPP1 were generally taken as proxies for all selenoprotein SECIS elements in terms of establishing a role for BP2. Yet the timing of expansion of these and specialization of the former to thyroid during the period of gene duplication may have tainted their representativeness. Possibly many other selenoproteins utilize KIAA0256 at least to some extent. That would account for the greater conservation of KIAA0256 and the difficulty finding SECIS elements in expected position for certain selenoproteins, ie their elements may be adapted to a different receptor and so have low Cove scores to the extent that tool is based on the BP2 fold paradigm.

Ribosomal protein L30 appears also to bind the SECIS kink-turn and play a role in selenocysteine insertion despite its meagre length of 114 amino acids. Likely many ribosomal proteins, L30 has remarkable sequence conservation, here still 94% at human-lamprey.

L30 has weak homology and secondary structure parallels to the pertinent region of BP2 and KIAA0256. These latter proteins might be viewed as domain composites that have accreted the kink-turn binding domain long ago from this undoubtedly ancient ribosomal protein. This opens a window on the origin of selenocysteine insertion in early eukaryotes.


SecisBpKink.jpg


L30 BP2.jpg


KIAA0256: the forgotten, misannotated SECIS binding protein

>SECISBP2_homSap Homo sapiens (human) full length
0 MASEGPREPESE 0
0 GIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTE 2
1 QKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFK 0
0 KKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKS 1
2 DGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDISLLREVVKPAAVLSK 0
0 GEIVVKNNPNESVTANAATNSPSCTR 1
2 ELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQK 0
0 SKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIE 0
0 DAEEFPNLAVASERRDRIETPKFQSKQQPQ 0
0 DNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVS 1
2 VGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKK 0
0 IILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELS 1
2 GPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRFRD 2
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHY 1
2 IEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL* 0

407–525 domain required for U insertion but not SECIS binding (399–516 in rat)
540     R540Q allele of SBP2 decreases GPX1 and DIO2
650–752 L7Ae motif kink-turn binding motif
676     invariant glycine (669 in rat)

>KIAA0256_homSap Homo sapiens (human) length=1101
0 MDRAPTEQ 0
0 NVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPFVQENQSNR 2
1 QFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPTPYSNTFQAANTVNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPK 0
0 QQLLQQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQT 1
2 DFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMN 0
0 HVESSMCA 1
2 GGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQ 0
0 VGFRCRGHSTSSERRQNLQKRPDNKHLSSSQSHRSDPNSESLYFE 0 
0 DEDGFQELNENGNAKDENIQQKLSSKV 0
0 LDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQ 0
0 EALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYT 1
2 VVTAASFHTKDSTNRKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKK 0
0 VILKEREEKKGRLTVDHNLLGSEEPTEMHLDFIDDLPQEIVSQE 1
2 DTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFRE 2
1 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1
2 ETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVP
GMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT* 0

phosphoserines predicted at SwissProt; no counterparts in SECISBP2
exon 8 skipped in RefSeq KIAA0256
exon 11 lacks counterpart in SECISBP2

Note the Irish proband with compound mutation K438stop/IVS8ds+29G/A (paternal allele inactive, maternal allele a splice donor mutation leading to early truncation) has been incorrectly described as a SECISBP2 knockout; in fact 48% production of wildtype maternal allele still occurs. Additionally, KIAA0256 may be able to partially compensate for reduction in level or loss of SECISBP2. Knockout mice for tRNA(Sec), unable to make any selenoproteins, die in utero.

In two earlier papers, the same authors in twice-published Figure 1B aligned full length SECISBP2 to an intermediate region of the KIAA0256 gene that happened to begin with a methionine, namely residues 422-849 of the 1056 residue protein (which includes the motif-bearing residues 632-829 of exons 14-16). Worse, the model KIAA0256 transcript was an exon-skipping minor splice variant and contains an additional exon 11 without counterpart in SECISBP2:

KIAA0256 originally arose in a GenBank submission package from a large-scale mRNA project at the Kaluza Institute. It skips over highly conserved exon 8 (which does not alter downstream reading frame since it resides in a series of consecutive phase 00 spliced exons). Modelling on this oddity, NCBI later confused the record by mixing in its own predicted genes (from genome assemblies without significant transcript programs) and labelling them mRNAs.

While baboon also has experimental transcripts skipping this exon (FC178616, FC178616), mammalian transcripts almost always retain the exon, for example human (AK307480), macaque (CJ457866), mouse (AK145135), rat (CK602552), dog (CO708934), horse (CX604216), cow (CK846448), sheep (EE864720), and even chicken (DR417186). SwissProt provides full length protein Q93073 without providing a supporting accession.

Transcription and its processing in mammals is a noisy process and artefacts abound. While exon-skipping in some cases may have physiological significance, lacking significant comparative genomics support, the null hypothesis is that they do not. Here the full length gene must contain exon 8 since it is quite conserved in amino acid sequence throughout tetrapods and assuredly ancestral. As all SECIS binding experiments to date used protein lacking exon 8; consequently we know nothing about the SECIS binding properties of intact protein.

Exon 8 comparative genomics:
VGFRCRGHSTSSERRQNLQKRPDNKHLSSSQSHRSDPNSESLYFE Homo sapiens 
VGFRCRGHSTSSERRQNLQKRPDNKHLSSSQSHRSDPNSESLYFE Macaca fascicularis
VGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRSDSNSESLYFE Tupaia belangeri
VGFRCRGHSTSSERRQNLQKRQDNKHLNSTQSHRSDPNSESLYFE Mus musculus 
VGFRCRGHSTSSERRQNLQKRQDNKHLNSTQSHRSDPNSESLYFE Rattus norvegicus 
VGFRCRGHSTSSERRQNLPKRQDNNKQLNASQSHRGDSNSESLYFE Canis familiaris 
VGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRGNPNSESLYFE Equus caballus 
VGFKCRGHSTSSERRQNLQKRQDNKQLNPNQSHRSDPNSESLYFE Myotis lucifugus
VGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRGDPNSESLYFE Bos taurus   
VGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRGDPNSESLYFE Ovis aries 
VGFRCRGHSTSSERRQNLQKKQDNKQLNSSQSHRGDPNSESLYFE Dasypus novemcinctus
VGFRCRGHSTSSERRQNLQKRQDNKQLNPIQSQRGDPNSESLYFE Loxodonta africana
VGFRCRGHSTSSERRQSLQKRQDNKPL-GNHSHRVETSSDPLYFE Monodelphis domestica
SGFRCRGHSTSSERRQNLQKRHE-KPLTTSQSSRAEQSPEPLYFE Gallus gallus 
PAFRCRGHSTSSERRQNLQKKPE-KPVSSSQSSKREQSPGSLYFE Anolis carolinensis
LGYRLRGQSTSSERRHNLQRKQDNKTGTPASSNKSGQSPDHLYFE Xenopus tropicali

KIAA0256 and SECISBP2 actually align moderately well over their entire lengths and have 17 near perfectly comparable exons (trillions:one odds for coincidence), meaning they reflect a segmental gene duplication. It is imperative to enforce exon boundaries to achieve true homological alignment of two proteins this diverged and so gappy N-terminally; structure-based alignment has different rules (allowing convergent evolution) and different goals.

The teleost fish Pimephales promelas has sufficient transcript coverage to allow recover of an accurate nearly full length KIAA0256 gene with a respectable 62% identity to human. (No fish has sufficient transcripts to recover full length SECISBP2.) That gene is shown below as homologically gapped exon-by-exon to human. Some early exons are quite well conserved over many billions of years of branch length, strong evidence that they retain an unknown function under fairly strong selection. However the gaps in other early exons are incompatible with retention of tertiary protein structure. No early pfam domain can be found.

>KIAA0256_pimPro Pimephales promelas (minnow) based on transcript tiling; exons by homology
0 MD-AGERK 0
0 DVKLSAEVEPFIPQKKGVEASLLPMSLCGEGGA----EPTQIPSYLITCYPFVQENQSNSR 2
1 QLPMYNGGDQRWQQLNPSPGGPYLAYPILSSPQPPVTSDYATYYHAIMPTPCPPVMGFYQPFPGPFAGPVPAG-VLNPVS-DCSDRPT---------SQRGRGVPRTPVLHK 0
0 QPMAQP-MRAKRPVMRSVAVQKEVCATGPDGRTKTVLLVDAAQQT 1
2 DFPGEASGSGAVRCVSDXASPQLWSNKARRXRTSQQ--ESSSEQGVSEADIDSDSGYCSPKH--NQGANNTSTNQHTPAA 0
0 A-VDAGVMT 1
2 A-VSWGNVSSQAVQK-PWPDRNTPFFRGSRTPERSYTQDFQ 0
0 MSFGCRA---AGPRRSTPPETP-NTHLT--------P--EPLYFQ 0 
0 DEDEFPDLATGGAAQRNKPDPVQPKLPKTL 0
0 LDNLPENSPISIVQTPIPITSSVPKRAKSQRKKALAAALATAQEYSEISMEQKKLQ 0
0 EALSKAAGKKSRTPVQLDLGDMLAALEKQQQAMRARQLNNTKPLSYT 1
2 VGTVSALHSKDCGSRVTGLKNTHT-PPHNILDSSAPRIKRGKEREIPKVKKTTAMKK 0
0 IILQEREVKKGKSSADQGVSGADEQRDS-LSFTDTLTQE---QD 1
2 ENGLSMPSDASLSPASQNSPYSITPVSQGSPASSGIGSPMAASAITKIHSRRFRE 2
1 YCNQVLSKDIDESVTLLLQELVRFQERVYQNEPSKAKAKRRLVMGLREVTKHMKLHKIKCVIISPNCEKIQAK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 ALFNTLVSLTEEARRAYKEMVSALEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1
2 ETNWRTMVENADAPEPPDSEP-ISRGNNRDQREVVSP---PP---QPT--ANQSLTP--SPGVARAPD--ESRTDDRLEWASL-STETGSLDGSGRDRLNSSHHSTTSTLVPGMLEEE...* 0

There is no reason to believe an odd fragment studied on a few SECIS sequences could accurately represent binding properties of full length protein in regards to the 25-odd orthology classes of SECIS elements. However these results became accepted folklore within the selenocysteine research community and the properties of full length KIAA0256 were never experimentally determined.

We have to wonder how sea urchin, which has a full length apparent ortholog of KIAA0256 on Scaffold18963:101,648-115,302 but nothing clustering to SECISBP2, can insert selenocysteine into its numerous selenoproteins (SEPHS1, SELU1, SELU2, SELM, SELO, SELW, SELN1, GPX3, GPX2, GPX4, GPX7,...). Unless a second copy has been lost, all SECIS interaction at the ribosome at sea urchin divergence appears to have been handled by KIAA056.

Using the kink-turn binding motifs of the two human proteins in turn as blastp query against the both collections of deuterostome KIAA0256 and SECISBP2 sequences, establishes KIAA0256 as the slower evolving protein by a wide margin. This fits KIAA0256 retaining ancestral function and its gene duplicate SECISBP2 specializing to a neofunctionalization. It's difficult to extend the table into invertebrates because of high divergence even in the L7ae region. The table shows Blastp score ratios KIAA0256/SECISBP2 relative to human query:

  galGal  1.41 72% identity
  anoCar  1.35
  xenTro  1.41 68% identity
  danRer  1.44
  tetNig  1.59
  takRub  1.45 64% identity
  gasAcu  1.60
  oryLat  1.52
  calMil  1.43 65% identity

It has not been previously noted that both proteins bristle with potential NxT/S x not P glycosylation sites, 13 for KIAA0256 and 6 for SECISBP2, with implications for cellular localization. These do not lie in homologous positions, unsurprisingly in view of the deep divergence of these genes and volatility of glycosylation sites as seen in other gene families, eg the 17 mammalian sulfatases. Even within orthologs of one gene here, they are conserved only to moderate depth (and that could be for reasons unrelated to glycosylation). Hence these site do not provide reliable anchors in region of poor sequence conservation.

Potential for phosphoserine conservation in exon 5 of KIAA0256:
DFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMN homSap
.FPSDIANKSLSESTATMLWKAKGRRRRASHPAVESSSEQGASEADIDSDSGYCSPKH-NNQSAPGALRDPASGTMN musMus
DFPSDIANKSLSESSATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSSTMN canFam
DFPSDIANKSLSESSSTMLWKSKGRRRRSSHPTAESSSEQGASEADIDSDSGYCSPKHSNNQATAMTSRNTDSGSIN monDom
DFPLDIANKSLSESAATVLWKSKGRRRRASHPAAESSSEQGASEADIDSDSGYCSPKHGNNQAAGPAARSADSGPAN ornAna G insertion
DFPSDIANKSLSESASTMLWKSKGRRRRASHPAAESSSEQGASEADIDSDSGYCSPKHGNNQAAAVTSRNADSCAMN galGal
DFPSEIASKSLSESMSTMHWKPKTRRRRSSHP-AESSSEQGASEADIDSDSGYCSPKHS-NQAAAVTSRSVESAAGN anoCar
DFPNEIANKTICESVGATPWKSKVRRRRLSHPAAESSSEQGASEADIDSDSGYCSPKHC--QAAAMCTRHADCGAV. xenTro
DFPGEASGGVRCVSDQVSPQQWKNKPRRRRTSQQESSSEQGASEADIDSDSGYCSPKH--NQGAA............ danRer
DFPGEVSGRCAAERASPQLWKNKTKRRRASHP-AENYSEQGASEADIDSDSGYCSPKH--NQAAGVTQR........ gasAcu
DFPGEAAVRCVSDQASPQLWSNKARRRRTSQ--QESSSEQGVSEADIDSDSGYCSPKHSTNQPAAAV----DAGVM  pimPro SGSG NQGANNT HT insertions
DFPDDIADKSLRDKPSPLLRKSKARRLASRRPQDPSSTDSEEDEGGIDSDSGYSSPKHGRNQSA..............braFlo
DFPEAIANKPLSDKTSNLTSRSKAKTRKKSQGNASSSSDSEVENTPHDSDSGYYSPLHAQQ................ strPur QTGRD insertion

Comparative genomics of 4 glycosylation sites in exon 7 of KIAA0256:
GGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQ Homo sapiens (human)
GGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQ Macaca mulatta (rhesus)
GGVNWPKVTCQATQKRPWMEKNQAFSRGGRQTEQRNNLQ Mus musculus (mouse)
GGVNWPKVTCQATQKRPWMEKNQAFSRGGRQTEQRNNSQ Rattus norvegicus (rat)
GSVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQ Canis familiaris (dog)
GGVNWSNVTSQATQKKPWMEKNQTFSRGGRQAEQRNNSQ Sus scrofa (pig)
GGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQ Equus caballus (horse)
GGVNWSNVTCQGTQKKPWLEKNQTFSKGGRQMEQRNNSQ Dasypus novemcinctus (armadillo)
GHVNWSNVTCQATQKKPWMEKHQTFSRGGRQTEQRNNAQ Loxodonta africana (elephant)
GGASWSNVTSQATQKKPWMEKSQPFSRGGRQTEQRNNSQ Monodelphis domestica (opossum)
.GVSWTNVNSQATQKKPWIEKTQTFIRGGRQAEQRNSSQ Gallus gallus (chicken)
AGATWANVSSQATQKKPWMERTPAFSRGGRQAEQHNSSQ Anolis carolinensis (lizard)

Reference set of 27 vertebrate SECIS BP2 L7Ae motif exons

>SECISBP2_homSap Homo sapiens (human) full length
0 MASEGPREPESE 0
0 GIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTE 2
1 QKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFK 0
0 KKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKS 1
2 DGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDISLLREVVKPAAVLSK 0
0 GEIVVKNNPNESVTANAATNSPSCTR 1
2 ELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQK 0
0 SKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIE 0
0 DAEEFPNLAVASERRDRIETPKFQSKQQPQ 0
0 DNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVS 1
2 VGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKK 0
0 IILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELS 1
2 GPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRFRD 2
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHY 1
2 IEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL* 0

>SECISBP2_panTro Pan troglodytes (chimp)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGPPALTEKEEPHY 1

>SECISBP2_macMul Macaca mulatta (rhesus)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKTMLENVQQELAGEPRPQAPPSPPTQGPSCPAEDGPPALTEKEEPHY 1

>SECISBP2_otoGar Otolemur garnettii (bushbaby)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKERRLVLGLREVLKHLKLKKLICVISPNCERQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKTMLENVQRELAGEPGPQVPSSLPMEGPSCSVEDSPPAPTEKEEPHY 1

>SECISBP2_tupBel Tupaia belangeri (tree_shrew)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRVVLGLREVLKHLKLKKLKCVIISPIZEKIQSK 1
2 GGLDDTLHTIIAYACAQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMEARQAYRSMLESARQELAGEPGLQAPPQPPVQGPRASSEGSAPAPTGRQEPHC 1

>SECISBP2_musMus Mus musculus (mouse)
1 YCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSK 1
2 GGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQSPPSPPMQDPIPSTEEGTLPSTGEEPHY 1

>SECISBP2_ratNor Rattus norvegicus (rat) exons 1416
1 YCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSK 1
2 GGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQ 0
0 FHKMVELTMAARQAYKTMLETMRQEQAGEPGPQTPPSPPMQDPIQSTDEGTLASTGEEPHY 1

>SECISBP2_cavPor Cavia porcellus (guinea_pig)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCIIISP 1
2 GLDDTLHTIIDYACAQNIPFVFALNRKALGRSLNKTVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKTMLENVRQELAGEPRPQMPPDPPSEGPSSSLEDTAPDPSAEEPHY 1

>SECISBP2_oryCun Oryctolagus cuniculus (rabbit)
1 YCSQMLSKEVDACVTDLFKELVRFHDLMYQDPVKATTKCQFELRVGKALDHLRLKKLKCIIVFPKHKKQS 1
2 TIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKTMLENMRHELAGEPGPPTPQPVQGPSCSAEDGPPAPTEGEVPHY 1

>SECISBP2_canFam Canis familiaris (dog)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHRMVELTMAARQAYKTMLENVRQELAGEPGTPALANPPMQGLGCSTQDSPPAPTEKEEPHY 1

>SECISBP2_felCat Felis catus (cat)
1 YCSQMLSKEVDACVTDLLRELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKIQSK 1
2 GGLDDTLHTIIGYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHRMVELTMAARQAYKTMLENARQELAGEPGPPAPGSPPPQPPAPAGRDEPRY

>SECISBP2_equCab Equus caballus (horse)
1 YCSQILSKEVDACVTELLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPCVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTKAARQAYKAMLENVHQELAGEPGPQAPASPPAQGPSCSTEGAPPAPTGKEEPHY 1

>SECISBP2_bosTau Bos taurus (cow)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKAKRRLVLGLREVLKHLKLRKLKCIIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACDQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYRTMLENARQELPGELGPCAPVGPPSQGPGCPVEDSPLAPTEKEEPHY 1

>SECISBP2_eriEur Erinaceus europaeus (hedgehog)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCIIISPNCEKIQSK 1
2 GGLDETLHTIIDCACEQNIPFVFALNRKALGRSLNKGVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKALLENMRQELAEESGSPAPSSPPVQSPSEDGPPAPAEKEEPHY 1

>SECISBP2_dasNov Dasypus novemcinctus (armadillo)
1 YCSQVLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGELDDTLHTIIDYAASRHSICVALNRKALGRSLNKAVPVSVVGIFSYDGAQ 0
0 DQFHKMVELTMAARQAYKAMLENVRKELAGEPGPRSPPSPPALGPHSSAGDVHPTSAGKEEPHY 1

>SECISBP2_loxAfr Loxodonta africana (elephant)
1 YCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGLDDTLHTIIDYACEQNIPFVFALHRKALGRSLNKPVPVSVVGIFSYDRAQ 0
0 DQFHKMVELTMAARQEYKTMLESVRQELAEEPRAGSPPSPPTQGPGCSAEVPRPAPTEKEEPRY 1

>SECISBP2_monDom Monodelphis domestica (opossum)
1 YCSQMLSKEVDDCVMDLLKELVRFQDRMYQKDPVKAKTKRRLVMGLREVLKHLKLKKLKCVIISPNCEKSKSK 1
2 GGLDETLHTIIDYACEQNVPFVFALNRKALGRSVNKVVPVSVVGIFSYDGAQ 0
0 DQFHKMIALTMEARQAYKIMLSTLKEEPALETENPPSPSLPRPSESCPSELGQTDPTQEEEPNY 1

>SECISBP2_triVul Trichosurus vulpecula (possum)
1 YCSQMLSKEVDDCVMDLLKELVRFQDRMYQKDPVKAKTKRRLVMGLREVLKHLKLKKLKCVIISPNCEKSKSK 1
2 GGLDETLHTIIDYACEQNVPFVFALNRKALGRSVNKVVPVSVVGIFSYDGAQ 0
0 DQFRKMIELTMEARQAYKVMLATLKEGAEALQTENPLPTSLTPQGQGCSSELSKTTDPTKEEEPNY 1

>SECISBP2_galGal Gallus gallus (chicken)
1 YCSQVLSKEVDSCVTDLLKELVRFQDRLYQKDPVKAKIKRRLVMGLREVLKHLRLKKLKCVIISPNCEKIQSK 1
2 GGLDETLHNIIDCACEQNIPFVFALNRKALGRCVNKAVPVSVVGIFSYDGAQ 0
0 DHFHRMVQLTTEARKAYKDMVAALEEELKELSKPLNZKSCLSETGKTSSTKEDIPNY 1

>SECISBP2_anoCar Anolis carolinensis (lizard)
1 YCTQVLSKEVDSCVTDLLKELVRFQDRLYQKDPVKAKTKRRLVMGLREVLKHLKLKKLKCVIISPNCEKIQSK 1
2 GGLDETLHLIIDSACEQNIPFVFALNRKALGRCLNKAVPVSVVGIFSYDGAQ 0
0 DYFHKMVELTMEARQAYKDMISALERELKKKTVRKKPLQSRPLDTVEASSTEEDVPDY 1

>SECISBP2_xenTro Xenopus tropicalis (frog) NM_001097262
1 YCSQVLSKDVDNCVMELLKELVRFQDRLFLKEPAKAKSKRRLVMGLREVLKHLKLQKLKCIIISPNCEKIQSK 1
2 GGLDDTLQTIISHACEQNVPFVFALNRKALGRCLNKAVPVSVVGVFSYDGAQ 0
0 DHFHKLCELTVQARQAYKDMIAAAQEQQSETEAGKNEEDPVAVNGQNKSDDMREESKAEEPDEPNY 1

>SECISBP2_danRer Danio rerio (zebrafish)
1 YCNQVLSKDVDECVSNLLKELVRFQDRLYQKDPMKARMKRRLVMGLREVLKHLKLKKVKCVIISPNCERIQSK 1
2 GGLDEALHNIIDTCRDQSVPFVFALSRKALGRCVNKAVPVSLVGIFNYDGAQ 0
0 DFYHKMIELSSEARTAYEVMLLNLEQTDAEEAQQTSPLAEKVETSSGDPQPEEPEY 1

>SECISBP2_tetNig Tetraodon nigroviridis (pufferfish)
1 YCNQVLSKEIDESVTLLLQELVRFQERVYQKDPTKAKSKRRLVMGLREVTKHMKLQTIKCVIISPNCEKIQAK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 DFYHKMIELSSEARIAYEVMLSNLEQTSAEEEPQTCTLAEKINTSSEDAQPEEPEY 1

>SECISBP2_takRub Takifugu rubripes (fugu)
1 YCTQMLSKDVDECVTTLLKELVRFQDRLYQKDPIKARMKRRIVMGLREVQKHLKLRKLKCVIISPNCERIQSK 1
2 GGLDEALHTIIDTCREQAVPFVFALSRRALGRCVNKAVPVSLVGIFNYDGAQ 0
0 DFYHKMIELSSEARTAYEVMLLNLEQTDAEEAQQTSPLAEKVETSSGDPQPEEPEY 1

>SECISBP2_gasAcu Gasterosteus aculeatus (stickleback)
1 YCNQVLSKEIDESVTMLLQELVRFQERIYQKDPTKAKTKRRLVMGLREVTKHMKLNKIKCVLISPNCEKIQAK 1
2 GGLDEALYNVIAMARDQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 DFYHKMIELSSEARRAYEVMVSSLEQTGQADPESVEEKLQISSAAEEAELGRDITPPEEPEY 1

>SECISBP2_oryLap Oryzias latipes (medaka)
1 YCSQMLRKDVDECVTVLLKELVRFQDRLYHKDPIKARMKRRLVMGLREVLKHLKLRKVKCVIISPNCEQIQSK 1
2 GGLDEALHTIIQTCREQAVPFVFALSRKALGHCVNKAVPVSLVGIFNYDGAQ 0
0 DHYHKMIELSAEARKAYEVLVSSLERDQQEESHPDRGTCFGSVTAEPEKPHY 1

>SECISBP2_calMil Callorhinchus milii (elephantfish) AAVX01044988
1 YCSQVLSKDVDSCVTDLLKELVRFQDRLYQKDPIKAKKKRRIVMGLREVLKHLKLKRLKCIIISPNCEKIQSR 1
2 GGLDDALHNIISIACEQEIPFVFALNRKALGQCVNKPVPVSVLGIFSYDGAE 0
0 NQFHQMVEITEEARKAYQEMLDALQQELEADEEKGDSEEQPLISSESSTIHFNNVTSQPFSEADEPEY 1

>SECISBP2_braFlo Branchiostoma floridae (amphioxus) extra exon
1 YCNQVLDKEIDATVTMLLQDLVRFQDRQYHK 00 DPIKAKAKRRIVMGLREVTKHLKLRKLKCIIIAPNLEKIQSK 1
2 GGLDDAIETILNLCMEQDVPFVFALGRKALGRAVNKLVPVSVVGVFNYDGAE 0
0 1

Reference set of 23 deuterostome SECIS KIAA0256 L7Ae motif exons

>KIAA0256_homSap Homo sapiens (human) length=1101 13 glycosylation sites
0 MDRAPTEQ 0
0 NVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPFVQENQSNR 2
1 QFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPTPYSNTFQAANTVNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPK 0
0 QQLLQQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQT 1
2 DFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMN 0
0 HVESSMCA 1
2 GGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQ 0
0 VGFRCRGHSTSSERRQNLQKRPDNKHLSSSQSHRSDPNSESLYFE 0 
0 DEDGFQELNENGNAKDENIQQKLSSKV 0
0 LDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQ 0
0 EALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYT 1
2 VVTAASFHTKDSTNRKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKK 0
0 VILKEREEKKGRLTVDHNLLGSEEPTEMHLDFIDDLPQEIVSQE 1
2 DTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFRE 2
1 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1
2 ETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVP
GMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT* 0

>KIAA0256_panTro Pan troglodytes (chimp)
2 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
0 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
1 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_macMul Macaca mulatta (rhesus)
2 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
0 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
1 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_tupBel Tupaia belangeri (tree_shrew)
1 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_musMus Mus musculus (mouse)
0 YCNQVLSKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
1 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
2 SLFNRLVELTEEARKAYKDMVAATEQEQAEEALRSVKTVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_ratNor Rattus norvegicus (rat)
2 YCNQVLSKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
0 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
1 SLFNRLVELTEEARKAYKDMVAATEQEQAEEALRSVKAVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_canFam Canis familiaris (dog)
1 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_equCab Equus caballus (horse)
1 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 SLFNKLVALTEEARRAYKDMVAALEQEQAEEASKNVKKGPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_dasNov Dasypus novemcinctus (armadillo)
1 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKG 1
2 GLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_monDom Monodelphis domestica (opossum)
0 YCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVKAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
1 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYCGAE 0
2 SLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_galGal Gallus gallus (chicken)
1 YCNQVLSKEIDECVTLLLQELVSFQERIYQKDPMRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 DLFNKLVSLTEEARKAYRDMVAAMEQEQAEEALKNVKKAPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_anoCar Anolis carolinensis (lizard)
1 YCNQVLSKEIDECVTLLLQELVSFQEQIYQKDPMRAKAKRRLVMGLREVTKHMKLSKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 NLFNKLVSLTEEARKAYRDMVAAMEQEQEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_xenTro Xenopus tropicalis (frog)
1 YCNQVLSKEIDECVTVLLQELVSFQERVYQKDPVKAKSKRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFSYSGAE 0
0 SLFHNLVSLTEEARKAYKDMVSSMEQEQAEEALKNIKKVHMGHSRNPSAASAISFCSVISEPISEVNEKDY 1

>KIAA0256_danRer Danio rerio (zebrafish)
1 YCNQVLSKEIDESVTLLLQELVRFQERVYQKEPSKAKAKRRLVMGLREVTKHMKLHKIKCVIISPNCEKIQAK 1
2 GGLDEALHNIIDTCRDQSVPFVFALSRKALGRCVNKAVPVSLVGIFNYDGAQ 0
0 GLFNKLVSLTEEARRAYKEMVSALEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1

>KIAA0256_tetNig Tetraodon nigroviridis (pufferfish)
1 YCNQVLSKEIDESVTLLLQELVRFQERVYQKDPTKAKSKRRLVMGLREVTKHMKLQTIKCVIISPNCEKIQAK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 SLFNQLVSLTEEARKAYKDMVSALEQEQTEEALKNEKKVPHQMGHYRNHSAASAVSFCSIFSEPISEVNEKEY 1

>KIAA0256_takRub Takifugu rubripes (fugu)
1 YCNQVLSKEIDESVTLLLQELVRFQERVYQKDPTKAKSKRRLVMGLREVTKHMKLQTIKCVIISPNCEKIQAK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNFSGAE 0
0 SLFNQLVSLTEEARKAYKDMVSALEQEQTEEALKNEKKVPHQMGHYRNHSAASAVSFCSIFSEPISEVNEKEY 1

>KIAA0256_gasAcu Gasterosteus aculeatus (stickleback)
1 YCNQVLSKEIDESVTMLLQELVRFQERIYQKDPTKAKTKRRLVMGLREVTKHMKLNKIKCVLISPNCEKIQAK 1
2 GGLDEALYNVIAMARDQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 GLFNRLVSLTEEARKAYKDMVSALEQEQAEEAQKNDKKLPHHMGHSRNHSAASAISFCSIFSEPISEVNEKEY 1

>KIAA0256_oryLap Oryzias latipes (medaka)
0 YCNQVLSKEIDESVTLLLQELVRFQERVYQKDPSKAKSKRRLVMGLREVTKHMKLHKIKCVIISPNCEKIQAK 1
1 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
2 GLFNQLVSLTEEARKAYKEMVSALEQEQAEEALKHDKKVPHHMGHSRNHSAASAISFCSILSEPISEVNEKEY 1

>KIAA0256_pimPro Pimephales promelas (minnow) based on transcript tiling; exons by homology; 62% identity
0 MDAGERK 0
0 DVKLSAEVEPFIPQKKGVEASLLPMSLCGEGGAEPTQIPSYLITCYPFVQENQSNSR 2
1 QLPMYNGGDQRWQQLNPSPGGPYLAYPILSSPQPPVTSDYATYYHAIMPTPCPPVMGFYQPFPGPFAGPVPAGVLNPVSDCSDRPTSQRGRGVPRTPVLHK 0
0 QPMAQPMRAKRPVMRSVAVQKEVCATGPDGRTKTVLLVDAAQQT 1
2 DFPGEASGSGAVRCVSDXASPQLWSNKARRXRTSQQESSSEQGVSEADIDSDSGYCSPKHNQGANNTSTNQHTPAA 0
0 AVDAGVMT 1
2 AVSWGNVSSQAVQKPWPDRNTPFFRGSRTPERSYTQDFQ 0
0 MSFGCRAAGPRRSTPPETPNTHLTPEPLYFQ 0 
0 DEDEFPDLATGGAAQRNKPDPVQPKLPKTL 0
0 LDNLPENSPISIVQTPIPITSSVPKRAKSQRKKALAAALATAQEYSEISMEQKKLQ 0
0 EALSKAAGKKSRTPVQLDLGDMLAALEKQQQAMRARQLNNTKPLSYT 1
2 VGTVSALHSKDCGSRVTGLKNTHTPPHNILDSSAPRIKRGKEREIPKVKKTTAMKK 0
0 IILQEREVKKGKSSADQGVSGADEQRDSLSFTDTLTQEQD 1
2 ENGLSMPSDASLSPASQNSPYSITPVSQGSPASSGIGSPMAASAITKIHSRRFRE 2
1 YCNQVLSKDIDESVTLLLQELVRFQERVYQNEPSKAKAKRRLVMGLREVTKHMKLHKIKCVIISPNCEKIQAK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAE 0
0 ALFNTLVSLTEEARRAYKEMVSALEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEY 1
2 ETNWRTMVENADAPEPPDSEPISRGNNRDQREVVSPPPQPTANQSLTPSPGVARAPDESRTDDRLEWASLSTETGSLDGSGRDRLNSSHHSTTSTLVPGMLEEE * 0

>KIAA0256_calMil Callorhinchus milii (elephantfish) AAVX01105236
1 YCNQVLSKDIDECVTLLLQELVRFQERVYQKDPIKAKMKRRLVMGLREVTKHMKLRKIKCVIISPNCEKIQSK 1
2 GGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAE 0
0 1

>KIAA0256_petMar Petromyzon marinus (lamprey)
1              LHKLRALIISPNCEKIQAK 1
2 GGLDEALQTVIALASEQSVPFVFALNRKALGHCLNKKVPVSVVGVFHYGGAE 0
0 THFQRLVALTEEARSAYRNMVSSLQRQEAAATSEPTGHTEDPLEASASPPSVPAHDPTALLHLLRPQQGPREDDPAEASGRSPGRNA 1

>KIAA0256_cioInt Ciona intestinalis (tunicate)
1 YCCQVLDKRVDEMSNQMLQRLVYFQDR 21 RLYKTDPAKAKRKRRVVLGFREVTKHLKMKKLRCVIISPNLEKIESK 1
2 GGLDDVLHEILDLCKEQNIPYVFALGKKALGRAVSKTVPVSIVGVFDYSGAE 0
0 1

>KIAA0256_strPur Strongylocentrotus purpuratus (sea_urchin)
1 YCNQVLDKDIDGCCTTLLQTLVKFQDRQYHKDPAK 00 AKMKRRLVMGLREVTKHLKLKKIKCVVVSPNLERIQSK 1
2 GGLDEAMDRISSLASEQNVPLIFALGRKALGRAVNKVVPVSVVGIFNYDGAE 0
0 DTYKQLLDLSTRARNAYADMVRKFQQELEAANAASAARMAKHRHHMGHNRNLFKG 1

Reference set of 10 deuterostome ribosomal L30 L7Ae motifs

>L30_homSap Homo sapiens (human) 4 exons numerous pseudogenes
0 MVAAKKT 0
0 KKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDP 1
2 GDSDIIRSMPEQTGEK* 0

>L30_tupBel Tupaia belangeri (tree_shrew)
0 MVAAKKT 0
0 KKSLESINSQLQLAMKDGKYVLGYKQTLKMIRQGKAKLVILANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRACTLAIMDP 1
2 GDSDIIRSMPEQTGEK* 0

>L30_ratNor Rattus norvegicus (rat) Sep15 Gpx4 Gpx1 Dio1 quite weak homology 35% with BP2 exons
0 MVAAKKT 0
0 KKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDP 1
2 GDSDIIRSMPEQTGEK* 0

>L30_myoLuc Myotis lucifugus (microbat)
0 MVAAKKT 0
0 KKSLESINSRLQLVMKSGKYLLGYKQTLKMIRQGKAKLVILANNCPALR 2
1 ISEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDP 1
2 GDSD-IRSMPEQTGEK* 0 

>L30_echTel Echinops telfairi (tenrec)
0 MVAAKKT 0
0 KNSLESINSRLQLVMKSGKYMLGYKQMLKMIRQGKAKLVVLANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGHNIELGTACGKSCRVCTLAITDP 1
2 GDADIIRSMPEQTGEK* 0

>L30_anoCar Anolis carolinensis (lizard)
0 MVAAKKT 0
0 KKSLESINSRLQLVMKSGKYVLGYKQTLKMIQQGKAKLVILANNCPALG 2
1 KSEIEYYAMLAKTGVHHYSGNNIEMGTACGKYYRVCTLAIIDP 1
2 GDSDIIRSMQEQTAEK* 0

>L30_danRer Danio rerio (zebrafish) 94%
0 MVAAKKT 0
0 KKSLESINSRLQLVMKSGKYVLGYKQSQKMIRQGKAKLVILANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDP 1
2 GDSDIIRSMPDQQQGGEK* 0

>L30_squAca Squalus acanthias (spiny dogfish) 97%
0 MVAAKKT 0
0 KKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDP 1
2 GDSDIIRSMPEQISEK* 0

>L30_petMar Petromyzon marinus (lamprey) 94%
0 MSAKKT 0
0 KKAIESINSRLQLVMKSGKYCLGYRQTLKMIRQGKAKLVLLANNCPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIEMGTACGKYYRVCTLAIIDP 1
2 GDSDIIRSMPEQQQPQPGDK* 0

>L30_braFlo Branchiostoma floridae (amphioxus) 84% to homSap
0 MKQK 0
0 RKTMESINSRLQLVMKSGKYVLGLKETLKVLRQGKAKLIIIANNTPALR 2
1 KSEIEYYAMLAKTGVHHYSGNNIELGTACGKYFRVCTLAITDP 1
2 GDSDIIRSMPAEDKGESK* 0

Positioning of SECIS elements in 3' UTR

SECIS DOI1.jpg

DIO2 SECIS.jpg

DIO3 SECIS.jpg

SEPN SECIS.jpg

SELM1 SECIS.jpg

SELM2 SECIS.jpg

SECIS GPX3.jpg

..................SECIS GPX6.jpg

GPX1 SECIS.jpg

SEPP1 SECIS.jpg

SEPHS2 SECIS.jpg

GPX2 SECIS.jpg

GPX4 SECIS.jpg

TXNRD1 SECIS.jpg

TXNRD3 SECIS.jpg

TXNRD2 SECIS.jpg

SELH SECIS.jpg

MSRB1 SECIS.jpg

SECIS SELI.jpg

SECIS SELK.jpg

SECIS SEPW1.jpg

SELO SECIS.jpg

SELS SECIS.jpg

SELT SECIS.jpg

SELV SECIS.jpg

SECIS SEPP2.jpg

Reference sets of 380 vertebrate SECIS elements

Introduction

The comparative genomics of SECIS elements can be investigated at much greater depth in the era of 50 completed vertebrate genomes. The situation currently is unsatisfactory since hardly any SECIS elements have rarely been submitted to GenBank, requiring manual entry from journal graphics prior to the approach described here.

The initial goal is obtaining 2-3 dozen phylogenetically dispersed orthologous vertebrate sequences for each SECIS element in each selenoprotein gene. After that, their evolution can be studied. To date, 380 SECIS elements have been obtained primarily from mammals, tetrapods, and fish. These collections can readily be leveraged to earlier diverging species by locating terminal coding exons and examining downstream sequence via uBlast against the seed set, hopefully in congruence to SECIS web tool motif recognition.

Functionality of a SECIS element depends not so much on its linear nucleotide sequence as its secondary and kink-turn tertiary fold which are experimentally established as critical to recognition by KIAA0256/SECISBP2 binding proteins. As long as hairpins retain complementary bases (perhaps straying intermittantly) and loops retain similar length, this constraint may be satisified without conservation of sequences (except at a handful of key residues).

This poses difficulties in recovering reliably orthologous sequences even in mammalian species (often wholly lacking in experimental transcript data) by blast query alone of an experimentally established fiducial query. Prospective elements might be validated by the SECIS web tool but this can yield both false positives and false negatives.

The approach here exploits the availability of a 30-species multiz whole-genome alignment which also provides a statistically sound PhastCons track quantitating peaks of cross-species conservation, notably in non-coding 3' UTR sequence where metazoan SECIS elements reside. Whole genome alignment methods provide more reliable truly syntenic alignment than ad hoc methods especially in non-coding regions.

It turns out that a rather small fraction of 3' mRNA has any notable PhastCons conservation and that SECIS elements of all human selenoprotein encoding genes reside at a PhastCons peak, whether or not (eg SELM) they are canonical. However the registration is sometimes imperfect, suggesting when the peak is broader that the SECIS element might be larger than the region favored by the SECIS web tool. Typically, 3' UTR of these genes contain other unexplained PhastCons peaks; these may or may not have any specific connection to the selenocysteine aspect of the gene.

Because human -- where the 30-species alignment track resides -- has an exhaustive set of selenoprotein transcripts, it is feasible to retrieve full length post-coding sequence and identify putative SECIS elements using the SECIS web tool. Blatting the identified SECIS elements back into the whole genome establishes that essentially all give unique matches not only within the expected 3' UTR position of the expected gene in correct strand orientation but also to a PhastCons peak.

Further, nucleotide sequences from species other than human, when recovered from the alignment details page for the PhastCons peak, are almost always identified as SECIS elements by the SECIS web tool which is based on PatScan and RNAfold rather than linear sequence homology. This provides independent cross-validation of the validity of the two methods.

Consequently the compilations below are orthologous in the classical sense within each gene. Within gene families, the SECIS elements are then paralogs (related by vertical genetic descent from last common ancestor preceding the gene duplication). However, different selenoprotein gene families may bear no detectable resemblance to each other even at the fold level even when sharing a CxxC motif. Conversely, the SECIS elements of SELM1 and diverged paralog SELM2 are radically diverged at supposedly invariant structural nucleotides.

SECIS elements of non-homologous coding regions could still themselves be homologous provided say an ancestral mobile element distributed a master element to unrelated genes. Alternatively, these elements arose from convergent evolution (perhaps kink-turn starting points were common in 3' UTR for other reasons) and were never orthologous.

This issue cannot be resolved by examining vertebrate (or even metazoan) selenoprotein genes because selenocysteine genes have far more ancient origins. Vertebrates are completely devoid of de novo originated selenoproteins. Their new selenocysteine genes appear to have arisen exclusively by segmental and retrogene duplication mechanisms which bring along the parental SECIS element. Their new selenocysteine sites within genes have arisen exclusively in existing selenocysteine genes that already have a functional SECIS element.

SEPP1a: 20 SECIS insertion sequences

>SEPP1a_homSap Homo sapiens (human) score: 30.80
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aauuagc aguuuag aauggaggaa

>SEPP1a_panTro Pan troglodytes (chimp) score: 30.80
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagc aguuuag aauggaggaa

>SEPP1a_macMul Macaca mulatta (rhesus) score: 30.80
uuuucuuuuu ccagugu ucuauuugcuuua augag aauagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagc aauuuag aauggaggaa

>SEPP1a_tupBel Tupaia belangeri (tree_shrew) score: 31.04
uuuucuuuuu ccaguau ucuauuugcauua augaa gacagaaacau aa acuaugaccuag ggguuucgguu ggau agguagc aauuuag aauggaggaa

>SEPP1a_musMus Mus musculus (mouse) score: 32.57
uuuccuuuuu ccagugu ucuaguuacauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau agcuugu aauuaag aacggagaaa

>SEPP1a_ratNor Rattus norvegicus (rat) score: 32.57
uuuucuuucu ccagugu ucuaguuacauug augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau agcucgu aauuaag aacggagaaa

>SEPP1a_cavPor Cavia porcellus (guinea_pig) score: 34.57
uguucuuuuu ccagaau ucuauuugcauug augaa aacagaaacau aa acuaugaccuag ggguuucuguu ggau acauagu aauuuag aauggaggaa

>SEPP1a_oryCun Oryctolagus cuniculus (rabbit) score: 33.28
uuuucuuuuu ccagcau ucuacuugcauua augau aacagaaacgu aa acuaugaccuag ggguuucuguu ggau aauuagua auuuag aauggagaag

>SEPP1a_sorAra Sorex araneus (shrew) score: 33.08
uuuucuucuu ccaauau ucuauuugcauua augaa gacagaagcaa aa acuaugaccuag gggcuucuguu ggau acuua gcaauugg gauggagaaa

>SEPP1a_eriEur Erinaceus europaeus (hedgehog) score: 33.29
uuuucuuuuu ccagcau ucuacuugcagua augag gacagaaacgu aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa

>SEPP1a_canFam Canis familiaris (dog) score: 33.38
uuuucuuuuu ccagcau ucuacuugcauua augaa aacagagacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa

>SEPP1a_equCab Equus caballus (horse) score: 29.34
uuuucuuuuu ccagcau ucuacuugcauua augag aacagaaacgu aa acuaugaccuag ggguuucugug ggau aguuagca auuuag aauggaggaa

>SEPP1a_bosTau Bos taurus (cow) score: 30.75
uuuucuuuuu ccaguau ucuacuugcguua augag aacagaaacgu aa acuauaaccuag ggguuucuguu ggau gguuggc aacuaag aauggaggaa

>SEPP1a_dasNov Dasypus novemcinctus (armadillo) score: 32.57
ucuucuuuuu ccagcau ucuauuugcauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggagaaa

>SEPP1a_loxAfr Loxodonta africana (elephant) score: 32.57
ucuucuuuuu ccagcau ucucuuugcauua augag aacagaaacau aa acuaugaccuag ggguuucuguu ggau aguuagca auuuag aauggaggaa

>SEPP1a_echTel Echinops telfairi (tenrec) score: 32.80
ucuucuuuuu ccagcau ucuuuuugcauua augag aacagaaacgu aa acuaugaccuag ggguuucuguu ggau acucugca auuuag aauggaggaa

>SEPP1a_monDom Monodelphis domestica (opossum) score: 30.77
uguuucucuu ccugugu ucugcuugcauua augaa gacagaagcau aa acuauaacuuag gggcuucuguu ggau aauuugca auccag aauggaggaa

>SEPP1a_ornAna Ornithorhynchus anatinus (platypus) score: 29.28
ugccuccugc cguucug cuugcauuu augag aacagaaacau aa acuauaaaccuag ggguuucuguu ggau agu uagcaau caagaauggg

>SEPP1a_anoCar Anolis carolinensis (lizard) score: 32.99
cacuucuacc auucugu uugcauuc augaa aacagaagccg aa acuaugaccuag gggcuuuuguu ugau auauu gcagcca agaacaggag

>SEPP1a_danRer Danio rerio (zebrafish) score: 32.87
uuucaccucu aagugcu uuauguggucuuu augaa ggcaggugcag aa acuaugcacuag uggugucuguc ugau guuu ggccau acagagcaga

SEPP1b: 16 SECIS insertion sequences

>SEPP1b_homSap Homo sapiens (human) score 20.32
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuau gguuaauacu

>SEPP1b_panTro Pan troglodytes (chimp) score 20.32
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuau gguuaauacu

>SEPP1b_macMul Macaca mulatta (rhesus) score 20.32
uauauugcuu aguaagu auuuccauaguca augau gguuuaauaggu aa accaaa cccuauaaacc ugac cuc cuuuac gguuaauacu

>SEPP1b_tupBel Tupaia belangeri (tree_shrew) score 16.22
uggacugcuu agaaagu auuuccauaguca augau gguucaauaggc aa acuaau cccuauaaacc ugaa cuc cuuuau gguuaauacu

>SEPP1b_oryCun Oryctolagus cuniculus (rabbit) score 15.69
cuuuaggcug cucagag uaucuccauauua augau gguuuaacaggu aa acuaaa cccuaugaacc ugaa uuu cuuuaug gauaauacua

>SEPP1b_sorAra Sorex araneus (shrew) score 15.19
uugguugcuu agaaagu auuuccauaguca augau gguuuaauaggu aa acuuauuu ccuguaaaccc ugaa cuu cuuuau gguuaauacc

>SEPP1b_canFam Canis familiaris (dog) score 16.12
ugauugcuua gaaagua uuuccauaguca augau gguucaauaggu aa acuaag uccuauaaacc ugaa cuccua uaugguu aauacuauua

>SEPP1b_equCab Equus caballus (horse) score 16.12
uugauugcuu agaaagu auuuccauaguca augau gguucaauaggu aa acuaag uccuauaaacc ugaa cuc cuuuau gguuaauacu

>SEPP1b_bosTau Bos taurus (cow) score 13.38
uugauugcuu agaaagu auuuccauaguca augau gguucaauaggc aa accagg uccuauaaacc ugaa uuu uuuuuau ggucaauacu

>SEPP1b_dasNov Dasypus novemcinctus (armadillo) score 14.48
uaggcugcuu agaaagu auuuccauaauca augau gguucaguaggu aa acuaag cccuauaaacc ugaa cuc cuuuau gguuaauacc

>SEPP1b_loxAfr Loxodonta africana (elephant) score 14.36
cuaggcugcu uagaagu auuuccaucauca augau gguucaauaggu aa accaaa uccuauaaacc ugaa cuc cuuaug guuaauacug

>SEPP1b_echTel Echinops telfairi (tenrec) score 17.68
uaggcugcuu agaaagu auuuccauaguua augau gauucauuaggu aa auuua gucuugugaauc ugaa cuc auuuau gguuaauacu

>SEPP1b_monDom Monodelphis domestica (opossum) score 16.17
cagguugcuu agaaagu guucccauaguua augau gguuuaacaggu aa auugac uccuguggacc ugaa cuc uuuuau gguucauacu

>SEPP1b_ornAna Ornithorhynchus anatinus (platypus) score 17.91
gaauggcuua gaaagua uuugccauaguua augac gguucaguaggg aa auccaa uccuaugaacc ugag cucuuc uaugguu aaugcuaaua

>SEPP1b_anoCar Anolis carolinensis (lizard) score 16.09
ugcuuagauu gugcuug ccauaguuc augau gguuuauuaggg aa auaaa uucuacaaaacc ugaa uuccu uuauggu gaacacagaa

>SEPP1b_danRer Danio rerio (zebrafish) score 24.26
auagaugguu uuaaaca uuuuuuauacuua augaa gguuuucuggu aa aucuuguauc accuggaagac ccgag aaac uguaugg aaauguaugc

SEPN: 14 SECIS insertion sequences

>SEPN_homSap Homo sapiens (human) score: 32.06
caguggcuuc cccggca gcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau guc uuugcag cugcaccuau

>SEPN_panTro Pan troglodytes (chimp) score: 32.06
gcaguggcuu cccuggc agcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau gucuuu gcagcug caccuauggg

>SEPN_macMul Macaca mulatta (rhesus) score: 32.06
caguggcuuc cccagca gcagcccc augau ggcugaauccg aa auccucga uggguccagcu ugau guc uuugcag cugcaccuau

>SEPN_musMus Mus musculus (mouse) score: 34.87
guggcucccc cagcaac agccgc augau ggcugggucug aa aucgcaaa uggauccagcc ugau guccuc gcaguug cacauguggg

>SEPN_ratNor Rattus norvegicus (rat) score: 35.19
gguguuuccc ccagcag cagccgc augau ggcugggucug aa aucccaaa aggauccagcc ugau guccucg caguug cacauguggg

>SEPN_cavPor Cavia porcellus (guinea_pig) score: 34.85
gaauaaugau ccccgag cagcagcccc augau ggcuggauccg aa auccuaga uggaucuagcu ugau gcc uuugcag uugcacuuau

>SEPN_sorAra Sorex araneus (shrew) score: 33.75
ggcuuuuccc cacccgc aaccgccuc augau ggcuggaucug aa auccuaga uggaucuggcu ugau gucuuu gcgauug uccuguggga

>SEPN_canFam Canis familiaris (dog) score: 34.73
ggcagugucu cccgcag cagcagcccc augau ggcuggaucug aa auccuaga uggguccagcu ugau guc uuugcag cugcaccuac

>SEPN_felCat Felis catus (cat) score: 28.82
cggugucucc cccagca gcagcccc augau ggcuggaucug aa auccuaga cgggcccagcu ugau guc uuugcag cugcaccugu

>SEPN_equCab Equus caballus (horse) score: 37.53
ggagggacaa uggcucc ucgcggcugcccc augau ggcuggaucug aa auccugga uggguccagcu ugau gucuc cgcaguug caccuauggg

>SEPN_bosTau Bos taurus (cow) score: 31.65
cgauggugcc cccuagc agccgcccc augau ggcuggaucug aa agcuuagg uggauccagcu ugau gucuuu gcaguug cuccuguggg

>SEPN_dasNov Dasypus novemcinctus (armadillo) score: 26.61
gccgcuggcu ccuccag cagccgccgc augaa ggauggaucug aa aucccaga uggauccagcc cgau cuc uuugcag uugcaccugu

>SEPN_loxAfr Loxodonta africana (elephant) score: 31.75
agugaugguu ccccaag caacugcccc augac agcugggucug aa auccuaga uggacccaguu ugau guc uuugcag uagcaccucu

>SEPN_monDom Monodelphis domestica (opossum) score: 26.99
gggacuucua uucuccu gcaacuguucuuu augau ggcuagauccu aa auccuaga ugggucaaguu ugau gucuug acaguaa cugaagggga

SEPHS2: 11 SECIS insertion sequences

>SEPHS2_homSap Homo sapiens (human) score: 20.81
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa accccauuaagg acugggagaggc agag caag ccucaga gcccaggccu

>SEPHS2_panTro Pan troglodytes (chimp) score: 20.81
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa accccauuaagg acugggagaggc agag caag ccucaga gcccaggccu

>SEPHS2_macMul Macaca mulatta (rhesus) score: 20.90
accugcaacc aucugac uuggucucuguua augac gucucucccucu aa acuccauuaagg acugggagaggc agag caag ccucaga gcccaggccu

>SEPHS2_otoGar Otolemur garnettii (bushbaby) score: 11.55
ccuaccagca ucugacu ucaucucugcug augac auuucucccuug aa aggcuac uaagggcaggg agaa gcagagga aguccca gcgcgcaggc

>SEPHS2_musMus Mus musculus (mouse) score: 22.00
aagacuagcc accugac uuggucucugaua augau gucucucccucu aa cucccaguaagg acugggagaggc ugaa caaac cucagag ccaggugucg

>SEPHS2_ratNor Rattus norvegicus (rat) score: 18.62
cagccaucua acuuggu cucuguua augac gccucucucugu aa accccacuacgg acugggggaggc agag caa acccag agcccaggcu

>SEPHS2_canFam Canis familiaris (dog) score: 20.27
ccugcaacca ucugauu uggucucuguua augac guuucucccucu aa accccuuuuagg acugggagaggc agag uaagccccag agcccaa accucagugg

>SEPHS2_felCat Felis catus (cat) score: 22.33
ccugcgacca ucugauu uggucucuguua augac gucucucccucu aa accccuuuaagg acugggggaggc agag caagccccag agcccaa gccuugaugg

>SEPHS2_equCab Equus caballus (horse) score: 21.57
ccugcagcca ucugacu uggucucuguua augac gucucucccucu aa accccguuaugg acugggagaggc agag caagccccag agcccagg ccuugguggu

>SEPHS2_bosTau Bos taurus (cow) score: 22.19
uccagccacc uuacuug gucucuguua augac gucucucucua aa ccccuuuaagga cugggagaggc agac caaac cccagag accaggauuu

>SEPHS2_dasNov Dasypus novemcinctus (armadillo) score: 17.60
acccguaacc accuggc cuggucucuguua augau guuucucccucu aa accccguuaagg acugggagaggc ggag ugagc cccagag cccaggccuu

SELM1: 18 SECIS insertion sequences

>SELM1_homSap Homo sapiens (human) score 27.34
agagugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuucuaggga uuuguguggau cagau acauac uuggcaa auuuuugagu

>SELM1_panTro Pan troglodytes (chimp) score 27.93
agagugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuucuaagga uuuguguggau cagau acauac uuggcaa auuuuugagu

>SELM1_macMul Macaca mulatta (rhesus) score 27.71
agggugaaac auucaca aagauuugcguua augaa gacuacacaga aa accuuccuaagga uuuguguggau cagau acauac uuggcaa auuuuugagu

>SELM1_otoGar Otolemur garnettii (bushbaby) score 28.3
gaaacauuca caaaaau uugcauua augaa gacuacacaga aa accuuucagagga uuuguguggau cugau acuuggc aaauuuug aguuuuauau

>SELM1_tupBel Tupaia belangeri (tree_shrew) score 24.54
agagggaaac auucaca aagauuugcguua augaa gacugcacaga aa accuuucuaggga uuuguguggau ccgau aau uggcaaa uuuuuguauu

>SELM1_musMus Mus musculus (mouse) score 35.23
aauuuaauac uuauaaa gguuugcauua augag gauuacacaga aa accuuuguuaagga cuuguguagau cugau aauuggcaaa uuuuua uuuuaaaagu

>SELM1_ratNor Rattus norvegicus (rat) score 30.11
aauguaauac uuauaaa gguuugcauua augag gauuacacaga aa accuuuguuaaggg uuugugucgau cugau aauuggcaaa uuuuua uuuuuaaaau

>SELM1_cavPor Cavia porcellus (guinea pig) score 31
gaaugaaaug gccacaa aaacuugcauua augag gacuauacaga aa accuuccuaagga uuuguauagau cugau guauggcaaa uuuuugu uuuuacauuc

>SELM1_sorAra Sorex araneus (shrew) score 25.76
uaagaauaau uugcaca aagauucgcauua augaa ggcuacacagg aa accuuacuaagga uuuguguggau cugau aac uagcaa auuuuugugc

>SELM1_eriEur Erinaceus europaeus (hedgehog) score 26.92
uagcaguacu cacaaag guuugcaucc augaa ggcuacauaga aa accuuacugagga uuuguguagau cugau gcucagcaaa cuucug uguuuuacag

>SELM1_canFam Canis familiaris (dog) score 27.8
agaguaucuu cacagag auuugcauua augaa gacuacacaga aa accuucaggagga uuuguguggau cugau auuuagcaa aauuuug uguuucacac

>SELM1_felCat Felis catus (cat) score 30.14
gagggaaaca uucacaa cgauuugcauua augaa gacuacacaga aa accuucaugagga uuuguguggau cugau gaua uuuagca aauuuuugug

>SELM1_equCab Equus caballus (horse) score 28.65
agugaaacau ucacaaa gauucgcguua augaa gacuacacaga aa accuuucugagga uuuguguggau cugau auccggcaaa uuuuug ugcuuuacau

>SELM1_bosTau Bos taurus (cow) score 23.97
gugaaauauu cacacaa agauuugcauua augaa gacuacacaga aa accuuccugagga uuuguguggac cugau acuuagcaaa uuuuug ugcuuuacau

>SELM1_dasNov Dasypus novemcinctus (armadillo) score 23.56
agagugaaac auuuaca aagauuugcacua augaa gacuacacaga aa accuuucuaagga uuuguauggau cugau auu uggcaaau uuuuguguuu

>SELM1_loxAfr Loxodonta africana (elephant) score 27.21
agagugaaac auucaca aagauuugcauua augaa gacugcacaga aa accuuuguaagga uuuguguggau cugau auu uggcaag uuuuuguguu

>SELM1_ornAna Ornithorhynchus anatinus (platypus) score 26.78
gacugugaaa caugaag acaaugcgcauua augau gacuacacaga aa accuaucaugga uuuguguauau cugau guuu cguguau uuccucaguu

>SELM1_anoCar Anolis carolinensis (lizard) score 31.51
gauuggagga ugccagc aaaauacucuuua augau gacuacaugua aa gccuuuaacaaaagg cauguguaggu cugau guca gaugua cuuuuguuaa

MSRB1: 14 SECIS insertion sequences

>MSRB1_homSap Homo sapiens (human) score: 26.23
ccugccagcc gcccugg cccuggucacugc augau ccgcucugguc aa acccuuccaggcc agccagagugg ggau ggu cugugac cugcugggaa

>MSRB1_panTro Pan troglodytes (chimp) score: 23.19
ccugccagcc gcccugg cccuggucacugc augau ccgcucugguc aa acccuuccaggcc agccagggugg ggau ggu cugugac cugcugggaa

>MSRB1_macMul Macaca mulatta (rhesus) score: 22.02
ccugccagcc gcccugg cccuggucacugc augau cugcucugguc aa acccuuccaggcc agccagcgugg ggau ggu cugugac cugcugggaa

>MSRB1_otoGar Otolemur garnettii (bushbaby) score: 25.09
uuggccaucu gcuccag cccaagucaaugc augau cuccucuggcu aa auccuuccaggcc agccagggugg ugau guc ugugacc ugcuggggga

>MSRB1_musMus Mus musculus (mouse) score: 23.75
ccugccaacc gcuccag ccucagucaccga augau cugcucugguc aa auccuucuaugcc agccagggugg ugau gac ccgugac cuuugaggag

>MSRB1_ratNor Rattus norvegicus (rat) score: 21.64
cuggccaacc acuccag ccucagucacugu augau cugcucugguu aa auccuucugugcca gcccagggugg ugau gaccugugac cuucgag gagggaggcg

>MSRB1_cavPor Cavia porcellus (guinea pig) score: 26.14
augaccagcu gcuucag cccuggucaaugc augau cuacucuggcu aa auccuucuaggcc agucagggugg ugau gau cugugac cugcugggga

>MSRB1_oryCun Oryctolagus cuniculus (rabbit) score: 28.41
auuggccccc gccccgg ucacugc augac ccgcucuggcu aa acccuuccagggc agccagggugg ugau ggu cugugac cugcggcggg

>MSRB1_canFam Canis familiaris (dog) score: 28.62
guugcuggcu gcugcag cugcagucacuac augau ucacucugguu aa acccuuccaggc agccagagugg ugau gau cugugac cugcuagagg

>MSRB1_felCat Felis catus (cat) score: 31.99
cucgccggcu gcuccgg cccuggucacuac augau ucacucugguc aa agccuuccaggc agccagagugg ugau gau cugugac ggcuggaggg

>MSRB1_equCab Equus caballus (horse) score: 24.02
cccagccggc ugcucca gcccagucacugc augau ucacucuggug aa acccuucggggc ggccagagugg ugag gaccug ugacccg cuggaggagc

>MSRB1_bosTau Bos taurus (cow) score: 27.78
ugccagcugc cccagcc cagucacucu augau ucucucuggcu aa acccuugcaggc agccagagugg ugau gacccgugac ccgcuggg ggagcaggcg

>MSRB1_ornAna Ornithorhynchus anatinus (platypus) score: 26.32
ucugccccuc cccaccu gguuuucagcauu augac ucgcccugggg aa agcccuccuggag cgccagggcga cgau ggucaccu gaucggg ugggcaggga

>MSRB1_galGal Gallus gallus (chicken) score: 22
ucuggugcua uucuggg cugggaucauggu augaa uuguccucugu aa auccuccugggau gcgagggugg ggau guu uuguga uccugcugga

TXNRD1: 17 SECIS insertion sequences

>TXNRD1_homSap Homo sapiens (human) score: 25.36
auuuggcagg gcaucga agggaugcaucc augaa gucaccagucuc aa gcccaugugg uaggcggugau ggaa caacug ucaaauc aguuuuagca

>TXNRD1_panTro Pan troglodytes (chimp) score: 25.36
auuuggcagg gcaucga agggaugcaucc augaa gucaccagucuc aa gcccaugugg uaggcggugau ggaa caacug ucaaauc aguuuuagca

>TXNRD1_otoGar Otolemur garnettii (bushbaby) score: 23.42
aucggcagug caucgac gggaugcgucc augaa gucaccagccuc aa gccugugugg ugggcagugau ggaa caacu guccaau caguuucuau

>TXNRD1_tupBel Tupaia belangeri (tree_shrew) score: 25.13
ucuuggcagc gcaucag agggaugcgucc augaa gucaccagccuc aa gcccgugcgg ugggcggugau ggaa cgacug ccagauc aguuucagca

>TXNRD1_musMus Mus musculus (mouse) score: 27.9
aucuggcaga gcaucac aggcaugcgucc augaa gucacuggccuc aa gcccaagug gugggcagugac agaa gagcu gccgggu cuguugagcu

>TXNRD1_ratNor Rattus norvegicus (rat) score: 28.03
uucggcagag caucacg gugcgucc augaa gucacuagccuc aa gcccaagugg ugggcagugac agaa agc ugucgau cuguuggguu

>TXNRD1_cavPor Cavia porcellus (guinea_pig) score: 23.88
gcggcggcac cguaggg ugcgucc augag gucaccagccuc aa gcccgaggg ugggcggugac ggau cgc gccgcg uggcucagcu

>TXNRD1_eriEur Erinaceus europaeus (hedgehog) score: 26.25
ugucagcaga gcaucaa agggaugcgucc augaa gucaccagccuc aa gcccgugcggg ugggcagugac ggaa cacug ucgaagc aguuucaaca

>TXNRD1_canFam Canis familiaris (dog) score: 24.54
auucggcaug caucggc guggugcgucc augaa gucacuggccuc aa gccaugcg gugggcagugau ggag caac ugucgag caguuuuagu

>TXNRD1_felCat Felis catus (cat) score: 24.14
acucggcagc gcaucgg agggcgcgucc augaa gucaccggcccc aa gcccccgcg gugggcggugau ggaa caagu gccgagc aguuuuagcg

>TXNRD1_equCab Equus caballus (horse) score: 21.76
acucggcagu gcaucga agggaugcgucc augaa gucacuggccuc aa agcccaugug gugggcggugau ggaa cagcug ucgaagc aguuuuagca

>TXNRD1_loxAfr Loxodonta africana (elephant) score: 22.55
auuggcagcg caucgag ggaugcaucc augaa gucacuggccuc aa gcccaugug gggggcggugau ggaa cagcu gucgaau cagcuuuggc

>TXNRD1_echTel Echinops telfairi (tenrec) score: 19.5
guggcagugc aucaaga gaugcguuc augaa aucgcuugcccc aa gcccga guggcgggcag cgau ggaaca ucugucu caucaguuuc

>TXNRD1_monDom Monodelphis domestica (opossum) score: 23.46
ggcucgcggu gcaucgg ugagaugcguuc augaa gucgcugccug aa gcccauaucccgugg uggguggugac cgaa agaaccg ccggcc uccguuuuau

>TXNRD1_ornAna Ornithorhynchus anatinus (platypus) score: 18.89
aggagugcac ccaaggg cugcauuu augaa gucagagccaa aa gccagcauuuugcgg uuggcugugau ggaa aaa cuccug ccacaguuuu

>TXNRD1_anoCar Anolis carolinensis (lizard) score: 32.53
uggcaaggca uuguuca agaugcuucc augaa gucacagucua aa accagugcuuucugg uaggcagugau ggaa aga uugcugg cacaacuuga

>TXNRD1_galGal Gallus gallus (chicken) score: 26.64
uagcagggca uuucaca caugcuuuc augaa aucacagccug aa gccugcacugucugg ugggcagugau ggaa gaacu gcugaca cagcugaaca

TXNRD3: 9 SECIS insertion sequences (problematic)

>TXNRD3_homSap Homo sapiens (human) score: 19.10
gacagcgaga agcagug ggacugcuucc uugac gccuuagcuu gg agccccguuaugaggu gagccaaggc ugac ucu cgcaagc caggacugag

>TXNRD3_panTro Pan troglodytes (chimp) score: 19.10 
agcagugggc GACAGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUU GG AGCCCCGUUAUGAGGU GAGCCAAGGC UGAC UCU CGCAAGC CAGGACUGAG

>TXNRD3_macMul Macaca mulatta (rhesus) score: 17.86 
GACuGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUU GG AGCCCuGUUgUGAGGU GAGCCAAGGC cGAC UCU CGCAAGC CAGGACUcAG

>TXNRD3_calJac Callithrix jacchus (marmoset) score: 25.26 
GACuGCGAGA AGCAGUG GGACUGCUUCC UUGAC GCCUUAGCUc Ga AGCCCuGUUAcGAGGU GAGCCAAGGC UGAu UCU CGCAAGC gAGGACUGAG

>TXNRD3_musMus Mus musculus (mouse) score: 21.86 
CUGACGGCAU GCAGCAG CCAGGCUGCUUCC UUGAC ACCUUGGCUC GG AACCUGCAGAGGU GAGCCAAGGC CGAC UUC UGCACGU CAGCCUCGAC

>TXNRD3_ratNor Rattus norvegicus (rat) score: 25.37 
cugauggcgu gcagcag ccaggcugcaucc uugac gccuuggcuc gg aaccugcagagg ugagccaaggc cgac ucc ugcacgu cagccucgac

>TXNRD3_canFam Canis familiaris (dog) score: 26.93
GCUGGCUGGA GAGGCAG GCAGGCUGCCUCC UUGAC GCCUUAGCUC GG AACCGCUGUGAGG UGAGCUAAGGC CGAU GUC CUCCAU GCCAGGCCAG

>TXNRD3_felCat Felis catus (cat) score: 20.14
CUGGCUgGGA GAGGCAG GucGGCUGCCUCC UUGAC GuCUUAGCUC GG AgcccgaUGUGAGG UGAGCUAAGGC CGAU Ggu cuuccac gucagaaucg

>TXNRD3_bosTau Bos taurus (cow) score: 12.55
GGCUGACGGG AGGGCAG ACUCGCUGCCUCC UUGAC GUCUUCGCUC AG AGCCGCCAGGU GAGCCAAGAC CGAC CUC UGCCCA CCAGCUCCUC

TXNRD2: 10 SECIS insertion sequences

>TXNRD2 homSap Homo sapiens (human) score: 31.00
cacccccccc caggcuc cuggugccagaug augac gaccugggugg aa accuacccugugg gcacccauguc cgag ccccc uggcauu ucugcaaugc

>TXNRD2 panTro Pan troglodytes (chimp) score: 31.00
ggcacccccc caggcuc cuggugccagaug augac gaccugggugg aa accuacccugugg gcacccauguc cgag ccccc uggcauu ucugcauugc

>TXNRD2 tupBel Tupaia belangeri (tree shrew) score: 36.55
cucccucccc aggcccc cgaugccagaug augac ggccuggacag aa acccacccuguggg cugcccagguc ugaa cccuccc uggugucu uuggggugua

>TXNRD2 musMus Mus musculus (mouse) score: 36.94
gccagccucu gacacuc ccagcgucagaug augau ggccugggcag aa accccauguggg ccgcccagguu ugaa ccccu ggcauuu cuagagcacu

>TXNRD2 ratNor Rattus norvegicus (rat) score: 34.71
cagccuucac acacugc cagugucagaug augac ggccugugcag aa acccccacguggg cugcccagguu ugaa ccccug gcauuu cuggagugcu

>TXNRD2 cavPor Cavia porcellus (guinea pig) score: 34.41
ucuggccccc caggucc ccagugccaguug augau ggccugggcag aa acccacccuguggg caguccauguc ugaa cuccc uggcauu ucuggagugc

>TXNRD2 eriEur Erinaceus europaeus (hedgehog) score: 34.68
ccagccccac caggccc ccgaugccagaua augau gacuugugcag aa acccacccggg cugcccauguc ugag ccucug uggcauu cuggagugua

>TXNRD2 canFam Canis familiaris (dog) score: 34.36
accagccccg ccaggcc ccgaugccagaag augac gacgugugcag aa accccccuguggg cugcccgcguc cgag cccccuggc guuucugg aauguaaaua

>TXNRD2 equCab Equus caballus (horse) score: 31.37
ccagcccugc cagguuc ccgaugccagacg augac gaccugcgcgg aa acccacccuguggg cugcccacguc cgag ccccc uggcauu ucugaagugc

>TXNRD2 echTel Echinops telfairi (tenrec) score: 37.41
cccuugcccc caccuca gcgccagaug augaa gacaugugcag aa acccagcccguggg cugcccauguc ugag ccccc ugacgu uucuggagug

SELS: 20 SECIS insertion sequences

>SELS_homSap Homo sapiens (human) score 36.61
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu

>SELS_panTro Pan troglodytes (chimp) score 36.61
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu

>SELS_macMul Macaca mulatta (rhesus) score 36.61
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuauc aa uggugagcccacca gugaggauuac ugau gugga caguuga ugggguuugu

>SELS_otoGar Otolemur garnettii (bushbaby) score 38.23
uaggacaguc ucuguga cagguugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau acaga caguuga ugggguuugu

>SELS_tupBel Tupaia belangeri (tree_shrew) score 40.14
gagaacaguc ucuguga cagggugcgucga augau gucuuccuuau aa auggugagcccacca cugaggaguac ugau gcaga caguuga caggguuugu

>SELS_musMus Mus musculus (mouse) score 41.68
caggaugguc ucuguga cgggaugcguuga augau gucuuccuuau aa auggugaacccacca gugaggauuac ugau guu cacagu ugacgggguu

>SELS_ratNor Rattus norvegicus (rat) score 40.42
cagggugguc ucuguga caggaugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau gua cacagu ugaugggguu

>SELS_cavPor Cavia porcellus (guinea_pig) score 40.42
aaggacaguc ucuguga cgagcugcguuga augau gucuuccuuau aa auggugagcccacca gugaggauuac ugau gcaga caguuga ugggguuuau

>SELS_canFam Canis familiaris (dog) score 39.26
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa acggugagcccacca gcgaggauuac ugau gcaga caguuga ugggguuguu

>SELS_felCat Felis catus (cat) score 41.01
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa auggugagcccacca gcgaggauuac ugau gcaga caguuga ugggguuguu

>SELS_equCab Equus caballus (horse) score 41.01
uaggacaguc ucuguga cagguugcguuga augau gucuuccuugu aa auggugagcccacca gcgaggauuac ugau gcaga caguuga uggguuguuu

>SELS_bosTau Bos taurus (cow) score 41.15
uaggacaguc ucuguga cagcuugcguuga augau gucuuccuugu aa auggugagcccacca gcaaggauuac ugau gcaga caguuga ugggguuguu

>SELS_eriEur Erinaceus europaeus (hedgehog) score 36.87
cucucuguga uggguug cguugg augau gucuuccuuguc aa uggugaacccacca gcgaggaucac ugau gcag acaguug augggguugu

>SELS_sorAra Sorex araneus (shrew) score 35.70
ugccgggccc gucucug ugauaggcgacga augac gucguccucgg aa auggugugccacca gcgaggaccac cgau gaagacacu ccugggc gccccccccc

>SELS_dasNov Dasypus novemcinctus (armadillo) score 35.89
uagaacaguc ucuguga cagguugcguuga augau gucuuccuuau aa aauggugaacccacca gugaggauuac ugau aauaga caguuga ugggguuugu

>SELS_echTel Echinops telfairi (tenrec) score 38.43
uagaacaguc ucuguga cagguugcguuga augaa gucuuccuuau aa auggugaacucacca gugaggauuac ugau aaaga caguuga ugagguuugu

>SELS_monDom Monodelphis domestica (opossum) score 40.64
uagaugaguc ucuguga caggcugcgcaga augau gucuuccuuau aa auggugagcucacca gugaggauuac ugau gauagauag uuguugg uguuuuuuuc

>SELS_ornAna Ornithorhynchus anatinus (platypus) score 33.47
ucaauaaguc ucuguga caggcggcauuga augau gucuuccuugu aa auggugaaacccacca gugaggauuac ugau aua gacagg agaugguauu

>SELS_anoCar Anolis carolinensis (lizard) score 25.44
gaaacucccu guaacaa gcagcaacaa augac gugguccuuau aa augguggacacauca cugaggaccuc cgaa gauaagacag cugauug gggacaguuc

>SELS_galGal Gallus gallus (chicken) score 35.60
cgggagaguc ucuguga caagcugcucugu augau guuuuccuuau aa augguaaacaaacca augaggauuac ugau gcua gacagca gauggggguu

SELT: 21 SECIS insertion sequences

>SELT_homSap Homo sapiens (human) score: 39.15
gaucauugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_panTro Pan troglodytes (chimp) score: 39.15
gaucauuuca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_macMul Macaca mulatta (rhesus) score: 39.15
gaucauugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_otoGar Otolemur garnettii (bushbaby) score: 39.15
gauuuuugca agagcag cgugacugacagu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_musMus Mus musculus (mouse) score: 39.15
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau guuucuugg caggcuc guuguaccuc

>SELT_ratNor Rattus norvegicus (rat) score: 39.15
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau guuucuugg caggcuc guuguaccuc

>SELT_cavPor Cavia porcellus (guinea_pig) score: 39.15
aauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uuuuug gcaggaucgu

>SELT_oryCun Oryctolagus cuniculus (rabbit) score: 39.15
ggauuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uuuuug gcaggcucgu

>SELT_canFam Canis familiaris (dog) score: 39.15
auuuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_felCat Felis catus (cat) score: 39.15
auuuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_equCab Equus caballus (horse) score: 38.49
gacuuuugca agagcag cguggcugacagu augaa ggccuguacug aa gacagcaagcugu uaguacagacc cgau gcu uucuug gcaggcucgu

>SELT_bosTau Bos taurus (cow) score: 39.15
gauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_eriEur Erinaceus europaeus (hedgehog) score: 39.15
gauuuuugca agagcag cgugacugacauu augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau gcu uucuug gcaggcucgu

>SELT_sorAra Sorex araneus (shrew) score: 35.80
ggauucucca agagcag cgcggcugcccuc augaa ggccugcacug aa gacagcagcugu uggugcaggcu ggau cuuccugg caggcuc guuguaccuc

>SELT_loxAfr Loxodonta africana (elephant) score: 36.15
gauuuuuuca agagcag cgugacugacauu augaa ggccuguacug aa gacagcgagcugu uaguacagacc agau gcu uuuuug gcaggcgcgu

>SELT_monDom Monodelphis domestica (opossum) score: 36.95
auuuuugcga gagcagc gugguuggcacca augaa ggccuguacug aa gacagcaagcugu uaguacagacc agau acuu acuuugc agccucguug

>SELT_ornAna Ornithorhynchus anatinus (platypus) score: 36.17
gaucuuucua agggcaa cgugauugaaacu augaa ggccuguacug aa ggcagcaaacugu uaguacagacc agau guuccu uugcagu cucguuguac

>SELT_anoCar Anolis carolinensis (lizard) score: 34.03
acaguuuuga aaggcaa caugaacgaaaua augaa ggucuguacug aa gacagcaugcugu uggugcagacu ggau acuucuc cucgccuu cauguuguug

>SELT_galGal Gallus gallus (chicken) score: 38.05
gugauuucca aggccgc gugucucggacca augaa ggccuguacug aa gacagcuugcugu ugguacagacu ggau gcuucucuu gcaguc acguugugcc

>SELT_danRer Danio rerio (zebrafish) score: 34.86
ccggucagcg ggacugu ggacuguggcaua augaa ggccugcgcugc aa acagcacacug uuggcacaggcu ggau gcu cagccac cacacacacu

>SELT_tetNig Tetraodon nigroviridis (pufferfish) score: 33.32
ggugggucuc ccugugg gcugugagguu augaa ggucugugcug aa ggcaggacgacugc uagcucagacu ggau gucccca ucacug uucaccgugc

SELO: 5 SECIS insertion sequences

>SELO_homSap Homo sapiens (human) score: 25.77
cugcccuggc ccaugca cacccgucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccggcuc agcagug cagccugguc

>SELO_panTro Pan troglodytes (chimp) score: 25.77
cugcccuggc ccaugca cacccgucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccggcuc agcagug cagcuugguc

>SELO_macMul Macaca mulatta (rhesus) score: 25.77
cugccugggc ccaugca caccugucuuucc augau ggcagagacau cc agucaggaccuga cccgucucuguc ugag gccagcuc agcagug cagccugguc

>SELO_monDom Monodelphis domestica (opossum) score: 24.43
gucuggggcc uccccga uggcugcuucucc augaa ggcagagaugu cc agucggcuccga cccgucucuguc cgac gcugac ucggca gcccgagcuc

>SELO_takRub Takifugu rubripes (fugu) score: 20.04
ccugcuugcc ccgaguu cuaccugcgaaua augac gacucagacaa ca agucugccagugac cugucugacuc ugaa cugugu ggugucg ccucagcaaa

SELV: 10 SECIS insertion sequences

>SELV_homSap Homo sapiens (human) score: 34.00
uuucucuccc aucuuag gagucucagcugg augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cuggggugag

>SELV_panTro Pan troglodytes (chimp) score: 34.00
uuucucuccc aucuuag gagucucagcggg augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cuggggugag

>SELV_otoGar Otolemur garnettii (bushbaby) score: 27.28
cuucucuccc aucucag gagccucgguagg augac gagaagggcug aa auauugccaugu cagguccuuuu cugau ggug gcuggga cugggguacg

>SELV_musMus Mus musculus (mouse) score: 33.37
cucucucccc aucucag gagccucagcagg augau gagaagggcug aa augcugccaaac cagguccuuuu cugau ggug gcugggg cuuggguggg

>SELV_ratNor Rattus norvegicus (rat) score: 33.37
uucucucccu gucucag gaaccucagcggg augau gagaagggcug aa augcugccaaac cagguccuuuu cugau ggug gcuggggc uugguuaggg

>SELV_cavPor Cavia porcellus (guinea_pig) score: 34.34
uuuucucccc auguuag gagcugcagcagg augau gagaagggcug aa auguuguugagu cagguccuuuu cugau ggugg cugggcu gaguggagcu

>SELV_equCab Equus caballus (horse) score: 32.67
uucucucucc aucucag gagccucggugag augac gagaagggcug aa auguugccaagu cagguccuuuu cugau ggcg gcugggg cugagguggg

>SELV_sorAra Sorex araneus (shrew) score: 26.16 
cuucucuccc caucuca ggaaccucagaag augaa gggaagggcug aa auguugg cagguccuuuu cugac agu ggcugug gcuaugaugg

>SELV_loxAfr Loxodonta africana (elephant) score: 34.00
uucucucccc aucucag gagccucagcaag augau gagaagggcug aa auguugccaagu cagguccuuuu cugau ggug gcugggg cugggguggg

>SELV_echTel Echinops telfairi (tenrec) score: 26.31
uucucucucc accccag gagccgcagcaag augac gagaagggcug aa augucgu caggcccuuuu cugag ggug gcugggg cuaggcucgg

SELH: 18 SECIS insertion sequences

>SELH_homSap Homo sapiens (human) score: 23.94
UUUGUGUCCC UGGUGAU GUUGGAACAUUA AUGAU GGAACAUGGCC AA ACUUC AGUCAUGAUCC UGAA GCC AUGGUU UCUUCCCUGC

>SELH_panTro Pan troglodytes (chimp) score: 23.94 
uuuguguccc uggugau guuggaacauua augau ggaacauggcc aa acuuc agucaugaucc ugaa gcc augguu ucuucccugc

>SELH_macMul Macaca mulatta (rhesus) score: 26.97 
cuuugugucc cugguga ugcuggaacauua augau ggaacauggcc aa acuuc agucaugugcc ugaa gccaugg uuucua ccccgccaga

>SELH_otoGar Otolemur garnettii (bushbaby) score: 22.59 
cuuucugugc uggugau guuggagcaugu augac gggacauggcc aa acuua agucaugugcc ugaa gcu acaguuu cuuccccucc

>SELH_tupBel Tupaia belangeri (tree_shrew) score: 26.55 
gcuuuuccug gugaugu ugaagggacauuu augau gggacauggcc aa acuuc agucaugugcc ugaa gcc aagguuu cuuccccucc

>SELH_musMus Mus musculus (mouse) score: 24.55 
cuuucagucc cuggaga uguugaagcauuu augau ggugcauggcc aa acuua agcuaugcacc ugaa gccauag uuucuu ccucaccaga

>SELH_ratNor Rattus norvegicus (rat) score: 23.97
cuuucagucc cuggaga uguugaagcauuu augau ggugcauggcc aa acuua agcuauguacc ugaa gccauag uuucuu ccucaccaga

>SELH_cavPor Cavia porcellus (guinea_pig) score: 19.25 
uuucuguucc ugguccu guuggggcgucu gugau gggacauggc ca aacuaaag ccauggccc ugaa gcc augguc ucuagcaucc

>SELH_canFam Canis familiaris (dog) score: 23.64 
agcauauccc uggugau guuggagcauuu augac ggaacauggcc aa acuuc agucauguacc ugaa gcc augguu ucuucccucc

>SELH_felCat Felis catus (cat) score: 24.80 
cuucucuccc uggugac guuuggagcauuu augac gggacauggcc aa auuuc agucaugugcc ugaa gcccug guuucu uccccuccag

>SELH_equCab Equus caballus (horse) score: 25.73
ccuucguccc ugguguu guuggagcauuu augac gguacauggcc aa acauc agucaugugcc ugaa gcu gugguuu cuuccccucc

>SELH_bosTau Bos taurus (cow) score: 28.39
ccucuguccc uggugau guuggagcauuu augac gggacauggcc aa acuuc agucauguccc ugaa gcu gugguu uccuccccuc

>SELH_sorAra Sorex araneus (shrew) score: 24.10
cuuucuguuc uggugau guuggagcauug augau ggaacaugacc aa acguc agucaugugcc ugaa gccaa guuucu uucucuccag

>SELH_dasNov Dasypus novemcinctus (armadillo) score: 25.97
cuucuauccu uggugau guuggagcauuu augau gggacauggcc aa acuuc agucauguacc ugaa gcca guuucu cccccuccag

>SELH_loxAfr Loxodonta africana (elephant) score: 25.83 
cuucuguccc uggugau guuggagcauuu augac ggaacauggcc aa accuc agucaugugcc ugaa gcc acgguuu cuuccccucc

>SELH_echTel Echinops telfairi (tenrec) score: 26.97
agucccgucc cugguga uguuggagcauuu augau ggaacauggcc aa acuuc agucaugugcc ugaa gcccguc uccuca cuuccagaaa

>SELH_monDom Monodelphis domestica (opossum) score: 26.74 
ugccuguccc cagugag uuuggagcaucc augau ggaaccugacc aa aucuccca gucacguccc ugaa gcuuggg cuccuu cuccugggaa

>SELH_anoCar Anolis carolinensis (lizard) score: 27.10 
auacauucuc ugugagu uggagcauuc augau gggauaugauc aa guggagcaaaucc agucacaucuc ugaa gcu guugcc cuccuccaca

SEPP2: 5 SECIS sequences

>SEPP2_SECIS_monDom Monodelphis domestica (opossum) chr2:9455773-9456962 score: 30 55 bp after stop codon
ACGUGCCGCU GCCCCUC CCUCCCUCCAAGA AUGAC GCCCACAGUGA AA CCCAGAGAACUGG UCCCUGUGGGC UGAU GCCC CAGAGGG GAGGAGAGGC

>SEPP2_SECIS_macEug Macropus eugenii (wallaby) SECIS score: 26.38 trace ti|975557399 contains terminal exon
CUUGCCCAUU GCCCUUC CCUCCCUCAAUUA AUGAU GCCCACAGUGA AA CCCGGGGAACCGG CCAUGGUGGGC UGAU GCCAU GGAGAAG AGGAAUGAGG

>SEPP2a_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 34.28
UCCCUCGACU CCCGCUC CCGCCUCGCACUC AUGAC GUCCACGGUGUC AA CCGGCCCGCCG GGCACCGUGGAC UGAC GCC GGUCGAG GCGGAGGGGU

>SEPP2b_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 22.82
GGAAUCAGGA ACCCAGU AAC AUGAG GUCAUCUUCGG AA GCCUGUGCCUAGAGGA CCAAGAUAAU GGAA AAAGUGACGG ACAAGGGU GUGUAGCUGG

>SEPP2_SECIS_tetNig Tetraodon nigroviridis (pufferfish) score: 17
GCUGGACCCA GGCUGCU GGUGGUCCCGUUG AUGAC GUCUGCGCUGGU AA ACCUGCCUGCAGG AGCCUGUGGAC CGAC GUG UGUGGAC CCACCGGCAG

SELI: 17 SECIS sequences

>SELI_SECIS_homSap Homo sapiens (human) score: 21.61
UUUCACUGAA UGAAGUU UGUGCUUGA AUGAA GAGUGUAUCUUA AA CCCCCUUUUUUUGGA CAGGCUGCACUU GGAU AAAAUA GGCACCA CUGUGUUGAU

>SELI_SECIS_panTro Pan troglodytes (chimp) score: 21.61
uuucacugaa ugaaguu ugugcuuga augaa gaguguaucuua aa cccccuuuuuuugga caggcugcacuu ggau aaaaua ggcacca cuguguugau

>SELI_SECIS_macMul Macaca mulatta (rhesus) score: 21.25
uuucacugaa ugaaguu ugugcuuga augaa gaguguaucuua aa ccuccuuuuuuugga caggcugcacuu ggau aacaua ggcacca cuguguugau

>SELI_SECIS_otoGar Otolemur garnettii (bushbaby) score: 21.25
uuucacuaag ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuuuuuuggac agguugcacuu ggau aaaaua ggcacca uuguguugau

>SELI_SECIS_musMus Mus musculus (mouse) score: 24.62
uuccacugaa ugaaguu ugugcuuaa augaa gagugugucuu aa acccuuuuuuuuggac agguugcacuu ggau aaaaua ggcacca cuguguugau

>SELI_SECIS_ratNor Rattus norvegicus (rat) score: 24.62
uuccacugaa ugaaguu ugugcuuaa augaa gagugugucuu aa acccuuuuuuuuggac agguugcacuu ggau aacaua ggcaccg cuguguugau

>SELI_SECIS_cavPor Cavia porcellus (guinea_pig) score: 17.42
uuccagugaa ugaaguu ugugcuuga augaa gaguguaucuua aa cccuuuuuuuuuugga cagguugcacuu ggau aaaaua ggcacca cuguguugau

>SELI_SECIS_oryCun Oryctolagus cuniculus (rabbit) score: 19.47
ucuacugaau gaaguuu gugcuuga augaa gaguguaucuua aa cccuuuuuuuuugga cagguugcacuu ggau aaaau aggcac cacuguugau

>SELI_SECIS_sorAra Sorex araneus (shrew) score: score: 8.13
uuccacugaa ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuauuuuguuuuuuugga cggauuacacuu ggau auaaua ggcacca uucuguugau

>SELI_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 14.43
cacggaauga aguaugu gcuuga augaa gaguguaucuu aa acccuuuuuuuuuuuugga cagguugcacuu ggau aua auaggc accacucugu

>SELI_SECIS_canFam Canis familiaris (dog) score: 14.04
uuccacugaa ugaaguu ugugcucga augaa gaguguaucuua aa cccuuuuuuuuuugga uggauugcacuu ggau aaaaua ggcacca cuguguugau

>SELI_SECIS_equCab Equus caballus (horse) score: 19.57
uuucacugag ugaaguu ugugcucga augaa gaguguauucuu aa acccuuguuuuugga uggauugcacuu ggau aaaaua agcacca cuguguugau

>SELI_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 17.76
cuacugaauu aaguuug ugcuuga augaa gaguguaucuu aa acccuuuguuuuuuugga cagguugcacuu ggau aaaa uaggca ccacuauguu

>SELI_SECIS_loxAfr Loxodonta africana (elephant) score: 25.81
uuccacugaa ugaaguu ugugcuuga augaa gaguguaucuu aa acccuuuuuuuuggac agguugcacuu ggau aaagua ggcacca cuguguugau

>SELI_SECIS_monDom Monodelphis domestica (opossum) score: 26.46
uucuacugaa ugcaauu ugugcuuga augaa gagugugucuu aa auccuuuauauggac aggcugcacuu ggag aga auaagca caaccauguu

>SELI_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 19.25
ucccagugaa ugaagcu ugugcuuga augaa gagugcaucuua aa cccauuuuuuuugga aaagcugcacuu ggag agaaag ggcacg acuguguuua

>SELI_SECIS_anoCar Anolis carolinensis (lizard) score: 22.02
uccccuuugu guguguc cuuugugcgugu augaa gagugcggccuc aa cccaggcgucuugga agggccgcaccc ggaa gaa acggagc acagcaaaga

>SELI_SECIS_galGal Gallus gallus (chicken) score: 24.62
uuuuauugag uuuauuu gugcuuaa augaa gagugcgcuuc aa acccagaccaggag agggcgcacuu ggag ugagc gagucaa accuugcucc

SELK: 19 SECIS sequences

>SELK_SECIS_homSap Homo sapiens (human) score: 34.53
acaaggacug cucugug uccucacagauga augag gucaugcuggg aa uucccucugcaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu

>SELK_SECIS_panTro Pan troglodytes (chimp) score: 34.53 
acaaggacug cucugug uccucacagauga augag gucaugcuggg aa uucccucugcaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu

>SELK_SECIS_macMul Macaca mulatta (rhesus) score: 36.14 
acaaggacug cucugug uccucacagauga augag gucaugcuagg aa uucccucuacaggga acuggccugac ugac augcaguuc cauaaa ugcagauguu

>SELK_SECIS_otoGar Otolemur garnettii (bushbaby) score: 31.99
caaggauugc ucugugu cuucacagauga augag gucaggcuggg aa uucucucuucaggga acuggccugac ugac augcagu ucuauaa acgcacuuuu

>SELK_SECIS_tupBel Tupaia belangeri (tree_shrew) score: 36.65
acaaggauug cucugug uccccacagauga augag guuaugccggg aa uucccuccacaggga ucuggccugac ugau acgcaguuc uauaaa ugcacauguu

>SELK_SECIS_musMus Mus musculus (mouse) score: 31.73
acaaggauug cucugug uccccacagauga augag gucaugcuggg aa uucccucugcagga ucuagccugac ugau acgcaguuc uauaaa uguacauguu

>SELK_SECIS_ratNor Rattus norvegicus (rat) score: 33.02
acaaggacug cucugug uccucacagaaga augag gucaugcuggg aa cucccucugcagga ucuggccugac ugau gugcaguuc uauaaa uguacaugug

>SELK_SECIS_cavPor Cavia porcellus (guinea_pig) score: 33.72
cucuguguuc ucacaga uaa augag gucacgccagg aa uucucucagcaggga ucuggcuugac ugau acgcagu ucucua aaugcauaug

>SELK_SECIS_oryCun Oryctolagus cuniculus (rabbit) score: 38.80 
accaggauug cucugug uccccacagauga augau gucaggcuggg aa uucccuccacaggga ucuggccugau ugag augcaguuc uauaaa ugcguauguu

>SELK_SECIS_sorAra Sorex araneus (shrew) score: 40.91
auaaggacug uucugug uccacacagauga augag gucaugcuggg aa uucccucuacgggga ucuggcaugac ugau augcag uucgaua aaugcacaug

>SELK_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 37.30
acaaggauug cucugug uucucacagguga augag guuaugcuggg aa uucccuccaugggga ucuggcaugac ugau augcaguuc uauaaa ugcacauguu

>SELK_SECIS_canFam Canis familiaris (dog) score: 36.30 
acaaggauug cucugug ccuucacagacgg augag guugugcuagg aa uucccuccccaggga ucuggcaugac ugac augcaguuc uauaaa ugcacauguu

>SELK_SECIS_felCat Felis catus (cat) score: 37.35
acgagaauug cucugug uccucacagacag augag gucgugcuggg aa uucccuccccaggga ucuggcaugac ugac augcaguuc uauaaa ugcacauguu

>SELK_SECIS_bosTau Bos taurus (cow) score: 39.16 
cucugugucc ucacaga cga augag gucaugcuggg aa uucccuccgcaggga ucuggcaugac ugac augcagu ucuaua aaugcacguu

>SELK_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 29.00
acaaggauug cucugug uccucacagauga augag gucauguuuggg aa uucccucugcaggg aucuggcaugac ugac uugcaguuc cauaaa ugcacauguu

>SELK_SECIS_loxAfr Loxodonta africana (elephant) score: 34.85 
acaaagacug cucugug uccccacagacgg augag gcugugcuggg aa uucccucugcaggga ucuggcauggc ugac augcaguuc cauaaa ugcacauguu

>SELK_SECIS_monDom Monodelphis domestica (opossum) score: 21.75
aagaauugcu cugucua cacagauua augau guugugcuggg aa cucccaucuuacagga uccaguguaac ugau ugcaa uuguaua aaugcacaug

>SELK_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 33.68
aauaauugug cugugaa caagcagauua augau guuuugcuggg aa uuccuucaggga uccaguauaac ugau aaagc aauuaua uaaaggcaca

>SELK_SECIS_anoCar Anolis carolinensis (lizard) score: 33.87
aauucccugc ucugcca auuggcgggacc augau guuguccuggg aa uuccuuauucuggga uccagggcaac ugaa aagcaguuc uguuaa auuaaaugca

>SELK_SECIS_galGal Gallus gallus (chicken) score: 30.90
ugagaacugu ucugcaa uauaagcagauga augaa guuguacuggg aa cuccuucaagga uccaguguaac ugaa gugcagug uuauuaa auacauguuu

GPX3: 15 SECIS sequences

>GPX3_SECIS_homSap Homo sapiens (human) score: 27.80
CACGGACCCCA UGGCAGG GGUGGCGUCUUC AUGAG GGAGGGGCCCA AA GCCCUUGUGGGC GGACCUCCCC UGAG CCUG UCUGAG GGGCCAGCCCT

>GPX3_SECIS_panTro Pan troglodytes (chimp) score: 27.80 
cacguacccc augucgg ggguggugucuuc augag ggaggggccca aa gcccuugugggc ggaccucccc ugag ccugu cugagg ggccagcccu

>GPX3_SECIS_macMul Macaca mulatta (rhesus) score: 27.80 
cacguacccc augucag ggguggcgucuuc augag ggaggggccca aa gcccuugugggc ggaccucccc ugag ccugu cugagg ggccagcucu

>GPX3_SECIS_tupBel Tupaia belangeri (tree_shrew) score: 29.38 
ccacaucccu gugucag ggguggcaucucc augag ggaggggcccg aa gcccuuguggg cggaccucccc ugag ccugu cugagg ggccggcccu

>GPX3_SECIS_musMus Mus musculus (mouse) score: 33.37 
cguguacccc aggucag ggguggugucucu augaa ggaggggcccg aa gcccuuguggg cgggccucccc ugag cccgu cuguggu gccagcccuu

>GPX3_SECIS_ratNor Rattus norvegicus (rat) score: 33.37 
caugugcucc aagucag ggguggugucucc augaa ggaggggcccg aa gcccuuguggg cgggccucccc ugag cccgu cuguggu gccagcccuu

>GPX3_SECIS_canFam Canis familiaris (dog) score: 29.96
cauguucccc gugucag gaauggcaucucc augaa ggaggggccc ga agcccucaugggc ggaccucccc ugag ccugu cugaag ggccggcccu

>GPX3_SECIS_felCat Felis catus (cat) score: 30.08 
ccacguccc gugucag ggauggcgucucc augaa ggaggggccc ga agcccuugugggc ggaccucccc ugag ccugu cugaag ggccagcccu

>GPX3_SECIS_equCab Equus caballus (horse) score: 26.20 
uacauucccc augucag ggguggcaucucc augau ggaggggcccg aa gcccugguggg cggaccucccc agag ccugu cugaag ggccagcccu

>GPX3_SECIS_bosTau Bos taurus (cow) score: 30.87 
cacguuccccg ugucagg gggcggcaucgcc augaa ggaggggcccg aa gcccgcguggg cgggccucccu ugag ccu gucugag gggccagccuu

>GPX3_SECIS_loxAfr Loxodonta africana (elephant) score: 16.32 
cuacgucccc gugucaa gagcggcaucucc augau gguggggcccg aa gccccugugg cggaccucccc agag ccugucc caugggc cagcccuu

>GPX3_SECIS_echTel Echinops telfairi (tenrec) score: 12.78 
ggcugugucc cgugcag agggagcaucucc augag ggugaggcccg aa gcccccgugg cggaccucgac ccgag ucug cucugg gccugccuuc

>GPX3_SECIS_monDom Monodelphis domestica (opossum) score: 22.94
ugaacauaag ggauggc aucucu augau ggugggaucca aa gccucuucaggg cggguuccauc agag ccugcaaaa gguguc aggacccuua

>GPX3_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 31.33
ugucccagaa uggggag guggcaucauc augac agcggggucug aa agccccuccugga uggaccccgcc cgaa ccug cucggcg guggcaugac

>GPX3_SECIS_anoCar Anolis carolinensis (lizard) score: 28.20 
GAGAUUUUGG GCCAAGG AAGUUGCAUCACU AUGAG GGUUAGGUCUG AA AGCUCCCAAAAAGAG CGGACCUAGCC UGAG GCUGCAAA GCUCUGGU GUAGCCCUUU

>GPX3_SECIS_galGal Gallus gallus (chicken) score: 30.65
GCCCUGGGGA GCAGAGG AUGACAUCUCC AUGAA GGCCUGGCCUG AA AGCCCCCACCAUGGGG UGGGCUCGGCC CGAU CCCG CCCAGGC GCGGUGCAGC 

GPX6: 10 SECIS sequences (most species have selenocysteine)

>GPX6_SECIS_homSap Homo sapiens (human) chr6:28,578,901-28,580,158 score: 18.10
cccaccucac augaagg gaagggcaucucc augau gguggauccc aa aaccccucuggguc gcacccugcc agag ccu uccuug gugccugucc

>GPX6_SECIS_panTro Pan troglodytes (chimp) score: 23.45
cccaccucac augaagg gaggggcaucucc augac gguggguccc aa aaccucucgggguc ggacccugcc agag ccu uccuug gugccugucc

>GPX6_SECIS_macMul Macaca mulatta (rhesus) score: 21.81 
accucauuca cagaagg gaggggcaucuuu augau ggugggucuc aa aaccucucuggguc agacccuacc agag ccu uccuug gugccugucc

>GPX6_SECIS_cavPor Cavia porcellus (guinea_pig) AAKN02051715 score: 19.91
AGAAGCCUCC CUAGAAG GAAGGGUGUCUCC AUGAU GGUGGGUCCC AA AAGCCCUGGAUC GGACCCUACC AGAA CCU UCCCUGG UGCCUGUCCU

>GPX6_SECIS_canFam Canis familiaris (dog) score: 24.33 but not found in 28way
CCUGGCCUCA UAUGAAA GGAGGGCAUCUCC AUGAU GGUGGGUUCC CA AGCCCCUGCGGUC GGACCCUACC AGAG CCU UCUUGG GUGCCUGUCC

>GPX6_SECIS_equCab Equus caballus (horse) score: 25.00
uucaucucac augagcu gaggggcaucucc augau gguggguccc aa agccccugugggc aggacccaac cagaa cucug ugccugu cccuuagugc

>GPX6_SECIS_bosTau Bos taurus (cow) score: 23.33 
cucacuucac augagga aaagggcaucucc augau gguggguccc aa agccucucuggguc ggaccccacc agag ccu uccuugg ugccuguccc

>GPX6_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 24.33
ccuggccuca uaugaaa ggagggcaucucc augau gguggguucc ca agccccugcgguc ggacccuacc agag ccu uccuugg ugucuguccu

>GPX6_SECIS_sorAra Sorex araneus (shrew) frag score: 22.95
uuucauauga aaggagg gggcaucucc augau ggugggucuc aa agccccucuggguc ggacccuacc agag cccugcugg guguccu gucccuuugu

>GPX6_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 19.82 
cucaccuuac augaagg gagggacauaucc augau gguggguccu aa agcccuucuggguc agacccuacc agaa ccu ucucug gugccugucc

>GPX6_SECIS_loxAfr Loxodonta africana (elephant) score: 19.28 
cucaccucac augaaug gaggggcauaucc augau gguggguccc aa agccucucuagguc ggacccuauc agaa ucuucccugg ugccugu cccuuagugc

>GPX6_SECIS_echTel Echinops telfairi (tenrec) frag score: 31.33 
ugugucccag aaugggg agguggcaucauc augac agcggggucu ga aagccccuccuggau ggaccccgcc cgaa ccu ucccug gugccugucc

GPX1: 17 SECIS insertion sequences

>GPX1_homSap Homo sapiens (human) score: 20.45
UGCUGUCUCG GGGGGGU UUUCAUCU AUGAG GGUGUUUCCUCU AA ACCUACGA GGGAGGAACACC UGAU CUUACAGAAA AUACCAC CUCGAGAUGG

>GPX1_panTro Pan troglodytes (chimp) score: 20.45 
gugcugcucu guggggg gguuuucaucu augag gguguuuccucu aa accuacga gggaggaacacc ugau cuuacagaaa auacccc cucgagaugg

>GPX1_macMul Macaca mulatta (rhesus) score: 26.45 
gcagcgcugc ucucugg gggguuuucaucu augag gguguuuccucu aa accuaca aggaggaacacc ugau aau acagaa aauacccccu

>GPX1_otoGar Otolemur garnettii (bushbaby) score: 25.30 
auagcgcugc ucucugg ggggguuucauuc augau aguguuaccucu aa acuugcau gggggaacacc ugau gcc ccagaaa auccccugag

>GPX1_tupBel Tupaia belangeri (tree_shrew) score: 21.14
cagcgcugcg ucugggg gguuucaucc augac ggugucuccucu aa accccga aggaggaacgcc ugau guccggaaaa cccccca ggugggcgcc

>GPX1_musMus Mus musculus (mouse) score: 29.78 
ggcugcacuc ugggggg cgguucuucc augau gguguuuccucu aa auuugca cggagaaacacc ugau uuccaggaa aaucccc ucagaugggc

>GPX1_ratNor Rattus norvegicus (rat) score: 25.72
ggcugcccuc cgggggg agguuuuucc augac gguguuuccucu aa auuuaca uggagaaacacc ugau uuccagaaa aaucccc ucagaugggc

>GPX1_cavPor Cavia porcellus (guinea_pig) score: 15.34 
uugcccagau gcucucc ugaggguucuucc augaa gguguuuccucuc aa ccugua uagaggaacauc cgau uccca ggaauu ucccagagag

>GPX1_oryCun Oryctolagus cuniculus (rabbit) score: 24.38 
guggccugcu gcucucu ggggguuucaucc augag ggcguucccccg aa aacaaa uggaggaacgcc ugau gucc gggaaac ccccaggugg

>GPX1_eriEur Erinaceus europaeus (hedgehog) score: 19.31 
auagccgcga gccgcug ggcaucucaucc augac ggcgccgccuuc aa accugcgagcag gaaggagcgcc cgau agc cgcgaga gcccccagcg

>GPX1_canFam Canis familiaris (dog) score: 22.40 
ucacagcgcu gcccucu ggggauuucaucc augau gguguuuccuug aa aucugca uggaggaacgcc ugau uucca ggaaagu ccccugagcu

>GPX1_felCat Felis catus (cat) score: 27.75 
cacagcacug cccucug gggauuucaucc augau ggcguuuccucg aa auuugca uagaggaacgcc ugau uuc cagaag aauccccuga

>GPX1_equCab Equus caballus (horse) score: 27.08
ucacagugcu uuucucu ggggauuucaucc augau ggcguuuccucu aa acaugc augaggaacgcc ugau guu aaggaga aucccccgag

>GPX1_bosTau Bos taurus (cow) score: 29.83 
agucagcgcu gcucucc agggauuuugccc augaa gguguucccucu aa accuacg uggaggaaugcc ugau gucca ggaaaau ccccugaggu

>GPX1_dasNov Dasypus novemcinctus (armadillo) score: 28.92
uguccuccac acggggu uuucaucc augac gguguuuccucu aa accugca gggaggaacacc ugaa guccggcaaa aucccc cgagaugggu

>GPX1_loxAfr Loxodonta africana (elephant) score: 25.48 
acuaggcggc uuuccgu ggggguuucauua augag gguguuuucucu aa accugaa uggaggaacacc ugau guc ugggaa gauacccccc

>GPX1_monDom Monodelphis domestica (opossum) score: 26.38 
gugcuaaggg uccguga ggguuuuaucu augau gguguuguuuu aa accauuaagga gaaagaacacu ugau aaugc uuguaa aaucccauga

>GPX1_ornAna Ornithorhynchus anatinus (platypus) score: 25.55
ugcuauuugc ccauggg ggagaucucauuu augau ggugcuccuucu aa accuuua cggaagagcacu ugau gga uccugag gaacuccaug

GPX2: 17 SECIS insertion sequences

>GPX2_homSap Homo sapiens (human) score: 29.54 
AGACUUGGGU AAGCUCU GGGCCUUCACAGA AUGAU GGCACCUUCCU AA ACCCUCA UGGGUGGUGUC UGAG AGGCGUGA AGGGCCU GGAGCCACUC

>GPX2_panTro Pan troglodytes (chimp) score: 29.54 
agacuugggu aagcucu gggccuucacaga augau ggcaccuuccu aa acccuca ugggugguguc ugag aggcguga agggccu ggagccacuc

>GPX2_macMul Macaca mulatta (rhesus) score: 29.54
agacuugggu aagcucu gggccuucacaga augau ggcaccuuccu aa acccuca ugggugguguc ugag aggcguga agggccu gaagccaccc

>GPX2_otoGar Otolemur garnettii (bushbaby) score: 27.86 
agacuugggu gggcucu gggccuucacaga augau ggcaccauccu aa acgccuc ugggugguguc ugag aagagcg gaaggcc uggagccacc

>GPX2_tupBel Tupaia belangeri (tree_shrew) score: 28.69 
agacuuaggu gggcucu gagccuucacaga augau agcaccuuccu aa acccccc cgggagguguc ugag aagugug acaggcc cggagccagc

>GPX2_musMus Mus musculus (mouse) score: 33.65 
agucuggggu agguucu gggccuucacaga augau ggcaucuuccu aa acccuuc ugggagauguc ugag aaguugug aaggguc cagagccagu

>GPX2_ratNor Rattus norvegicus (rat) score: 30.80 
cugggguagg ugcuagg ccuucuucacaga augau ggcaucuuccu aa acccuuc ugggggauguc ugag acg uugugaa gggcccagag

>GPX2_cavPor Cavia porcellus (guinea_pig) score: 20.08 
cuaggacagg uggcucu gggccuucacaga augac ggcaccguccu aa acgcua ugggugguauc ugag aagugug aauggcug gagccagccu

>GPX2_sorAra Sorex araneus (shrew) score: 29.00 
aagcuggggc aaacucu gggccuucgcaga augau ggcaccucccu aa auccau ggggugguguc ugag gcgugcg agggccu ggaaacagcc

>GPX2_eriEur Erinaceus europaeus (hedgehog) score: 25.06 
aaagcugggu gguuucu ggaccuucacaga augau agcaccuuccu aa accuaua gggaugguguc ugag aaaugu gaagggc cugaaguaaa

>GPX2_canFam Canis familiaris (dog) score: 22.57 
aagacuuggg uggcucu gggccuucacaga augau ggcaccuuccu aa auagua ugggcgguguc ugag aagugug aagggcu cagagccagc

>GPX2_felCat Felis catus (cat) score: 22.45 
aagacuuggg uggaucu gggccuucacaga augau ggcaucuuccu aa acugua ugggcgguguc ugag gaguguga agggcu cggagccagc

>GPX2_equCab Equus caballus (horse) score: 28.45
agacuucggu aggcucu gggccuucacaga augau ggcaccuuccu aa accugua uggacgguguc ugaa aagcgug aagggcc ccgagucagc

>GPX2_bosTau Bos taurus (cow) score: 26.14
agacaugggu gggcucu gugucuucacaga augau ggcaccuuccu aa aucugua ugggcgguguu ugag aagagu gaaggcc uggagccagc

>GPX2_loxAfr Loxodonta africana (elephant) score: 27.08 
agacuugggu aggcucu ggaccuucgcaga augau ggcaccuuccu aa acucag ugggugguguc ugag aaaugug aagggccu agggccagcc

>GPX2_echTel Echinops telfairi (tenrec) score: 29.95 
agugcuggug uggcucu gggccuucacaga augau ggcaccuuccu aa acccuc cggaagguguc ugag aaaugug aagggcc uggggccggc

>GPX2_monDom Monodelphis domestica (opossum) score: 26.38 
gugcuaaggg uccguga ggguuuuaucu augau gguguuguuuu aa accauuaagga gaaagaacacu ugau aaugc uuguaa aaucccauga

>GPX2_ornAna Ornithorhynchus anatinus (platypus) score: 27.55
gggcucgagc agccucc agaccuucacaga augac ggugucuccuu aa acccuaac cgggaggcacc cgag agccggu gaagggc cuggugacug

GPX4: 14 SECIS sequences

>GPX4_SECIS_homSap Homo sapiens (human) chr19:1,057,512-1,057,793 score: 29.19
CCACGCCCUU GGAGCCU UCCACCGGCACUC AUGAC GGCCUGCCUG CA AACCUGCUGGU GGGGCAGACC CGAA AAUCC AGCGUGC ACCCCGCCGG

>GPX4_SECIS_panTro Pan troglodytes (chimp) score: 29.19
CCACGCCCUC GGAGCCU UCCACCAGCACCC AUGAc ggccugccug ca aaccugcuggu ggggcagacc cgaa aaucc agcgugc acccugccgg

>GPX4_SECIS_macMul Macaca mulatta (rhesus) score: 33.09
CCACGCCCUC GGAGCCU UCCACCGGCACCC AUGAc ggccugcuugc aa accagcuccuggu gaggcagacc cgaa aaucc agcgugc accccgcugg

>GPX4_SECIS_tupBel Tupaia belangeri (tree_shrew) score: 31.05 
CCGCGCCCCG GAACCUU CCACCCGGCACCU UUGAc ggucugccuau aa accugccacug gugaggcagacc cgag aaccu ggcgugc acccugccgg

>GPX4_SECIS_musMus Mus musculus (mouse) score: 35.62 
UGACCCCUGG AGCCUUC CACCCCGGCACUC AUGAa ggucugccug aa aaccagccugcuggu ggggcagucc ugag gaccu ggcgugc acccugccgg

>GPX4_SECIS_ratNor Rattus norvegicus (rat) score: 34.33
UGACCCCUGG AGCCUUC CACCCCGGCACUC AUGAc ggucugccug aa aaccagcccgcuggu ggggcagucc cgag gaccu ggcgugc accccgccgg

>GPX4_SECIS_cavPor Cavia porcellus (guinea_pig) score: 34.46 
UGGCCGCCCC GAGUCUC CUACCCGGGUGCC AUGAc ggccugccug ca aaccagcgug cugguggggc agac ccg aggaugc gugcacugcc

>GPX4_SECIS_canFam Canis familiaris (dog) score: 31.12 
AUGCCCCUCG GAGCCUU CCACCCGGCACCC AUGAc agucugucuaa aa accagcccgcugg uggggcagacc cgag aaccc ggcgugc acccugccgg

>GPX4_SECIS_sorAra Sorex araneus (shrew) score: 36.85 
CUGCCCCUCG GAGCCUU CCACCCGGCGCCC AUGAc ggucugccugc aa accagccc gcugguggggc agac ccgagaaccc ggcgugc accuugccgg

>GPX4_SECIS_bosTau Bos taurus (cow) score: ?
tgttccgagaAGCCTTCCCCCGGtgCctATGACGGTCTGtCTGAAAACCAGCCCCTGGTGGGGCAGaCCtGAGaACCTGGCGTGCACtccttccgg

>GPX4_SECIS_echTel Echinops telfairi (tenrec) score: 40.88
UUGAUCCCCA GAGUCUU CCACCCGGCACCA AUGAc ggucugccuuc aa accaggccucugg ugaggcagacc cgau gaccc ggcgugc acucagccgg

>GPX4_SECIS_monDom Monodelphis domestica (opossum) score: 40.88 
UUGAUCCCCA GAGUCUU CCACCCGGCACCA AUGAC GGUCUGCCUUC AA ACCAGGCCUCUGG UGAGGCAGACC CGAU GACCC GGCGUGC ACCUCAGCCG

>GPX4_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 33.89
ACCUCCGCUU UCCCGGG ACGCUCUGCCUCC AUGAc ggccggccuu ca agccaaaaccaguugg uggggccggcc ugaa caa accggca cgggucccgg

>GPX4_SECIS_anoCar Anolis carolinensis (lizard) score: 38.77
UGCUCCCCGU GGGCCCC CUCCUCCAGCACC AUGAc ggccugccuug aa gccagcuugcugg ugaggcagacc cgaa gauuc ggcgugc acugcuggag

>GPX4_SECIS_galGal Gallus gallus (chicken) score: 38.77
UGCUCCCCGU GGGCCCC CUCCUCCAGCACC AUGAc ggccugccuug aa gccagcuugcugg ugaggcagacc cgaa gauuc ggcgugc acugcuggag

SEPW: 13 SECIS sequences

>SEPW_SECIS_homSap Homo sapiens (human) score: 36.01
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG

>SEPW_SECIS_panTro Pan troglodytes (chimp) score: 36.01
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUuGUGG CUGCUGUUGG

>SEPW_SECIS_ponPyg Pongo pygmaeus (orang_sumatran) score: 30.55
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAAUCUUGUGGACACC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG

>SEPW_SECIS_macMul Macaca mulatta (rhesus) score: 33.55
GACCCAGCCC CUCUCAG CAGACGCUUC AUGAU AGGAAGGACUG AA AAGUCUUGUGGACgCC UGGUCUUUCCC UGAU GUU CUCGUGG CUGCUGUUGG

>SEPW_SECIS_musMus Mus musculus (mouse) score: 34.04
UUGGCCCAGC CCCUCGU GGCAGACGCUUC AUGAU GGGAAGAACUG AA AUGUCUCGUGGACGC CUGGUCUUUCC CUGAU GUCCCU GCGACUG CCACGUAGGG

>SEPW_SECIS_ ratNor Rattus norvegicus (rat) score: 26.55
UGGCCGGCCU UUCUUGG CAGCCGCUUC AUGAC AGGAAGGACUG AA AUGUCUCAAAGACCUG UGGUCUUUCUU CGAU GUU CCUGCGG CCACCAAGUC

>SEPW_SECIS_canFam Canis familiaris (dog) score: 34.04
UUGGCCCAGC CCCUCGU GGCAGACGCUUC AUGAU GGGAAGAACU GA AAUGUCUCGUGGACGCC UGGUCUUUCC CUGAU GUCCCU GCGACUG CCACGUAGGG

>SEPW_SECIS_susScr Sus scrofa (pig) no SECIS element found
AGTAACCTTGACCCAGCCCCTTTCATGCCTCAGCCTCGTCTCCATAGGCTAAGACTGGAGAAGTCTTGTGGACGCCTGGTCTTTCCCTGATGTTCTCGTGGCTGCTGTTGGGGGCAGAGATGGATGAGCTGGTCTTTAC

>SEPW_SECIS_borAnc Boreoeuthere ancestralis (ancestral) score: 33.54
GGCCCAGCCC CUCUCAG CAGAUGCUUC AUGAC AGGAAGGACUG AA AUGUCUUGUGGACGCC UGGUCUUUCCC UGAU GUU CUUGUGG CUGCUGGUUG

>SEPW_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 28.71
CCCAGCUGCC CUUGGCA GACGCUUC AUGAG GGGAAGGACCU AA AUGCGUCGUGGAUGCC UGGUCUUUCCC UGAU GCUCCUUCAC CUGCCAG AUGGGGCAGA

>SEPW_SECIS_loxAfr Loxodonta africana (elephant) no SECIS element found
GGGACCTTGGCCCAGCCCCTTTCAGCAGACACTTCATGACAGGAGGACTGAAATGTCTCCCAGACGCCTGGCTCTTTCCCTGAATCTGTCGGCTGCAGGACAGGGCAGCGGTTGACTCTCTCGTTTTTTGCAT

>SEPW_SECIS_echTel Echinops telfairi (tenrec) no SECIS element found
AGGCCAGAGACCTTGGCCCAGTCCCTCCATGACAGGCAGAACTGAAATGTCCTCTGGACAAGTGGTCTTTTCCAGAAACCCCAGGGCTGCTGGGCCGGAGCCGAGGCTGACAACCCTGGTCTTTGCCT

DIO1: 8 SECIS sequences

>DIO1_SECIS_homSap Homo sapiens (human) score: 29.16
uuuuaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag

>DIO1_SECIS_ponPyg Pongo pygmaeus (orang) score: 29.16
uuuuaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag

>DIO1_SECIS_macMul Macaca mulatta (rhesus) score: 29.16
uuucaacucu gugucuu uacauauuuguuu augau ggccacagccu aa aguacaca cggcugugacu ugau ucaa aagaaa auguuauaag

>DIO1_SECIS_cavPor Cavia porcellus (guinea pig) score: 23.71
uguuaacucu gcuucuu uucauauuuguuc augac ggucacagucu aa aguacaca cagcugugacc ugau uuga aagaaa auguuuuaag

>DIO1_SECIS_bosTau Bos taurus (cow) score: 27.83
uuuaacucug ccucuuu ucauauuuguuc augac ggccacagccu aa aguacaca cggcugugacu ugau uug aaagaa aauguuuuaa

>DIO1_SECIS_sorAra Sorex araneus (shrew) score: 23.57
ggaaacucag cuucucu ucauauuuguuu augac agccccagcug aa aguacaca cagcuguggcu ugau ugg aaagaa aauguuuuaa

>DIO1_SECIS_eriEur Erinaceus europaeus (hedgehog) score: 25.87
uuuaacucug cuuucuu cucauauuugcuu augau ggucacagcuu aa aguauaca cagcugugacu ugau ugg aaagaa aauauuuuaa

>DIO1_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 23.83
cccggauccg guuccgu gaauauugguuu augag ggucacagugu aa agcgcaug cagcugugacu ugau cug agaaaau auuucugcgg

DIO2: 12 SECIS insertion sequences

>DIO2_SECIS_homSap Homo sapiens (human) score: 29.74
cagagaugug cagaguu gaccagugugcgg augau aacuacugacg aa agagucaucgacuc aguuagugguu ggau guaguc acauuag uuugccucuc

>DIO2_SECIS_macMul Macaca mulatta (rhesus) score: 29.74
cagagaugug cagaguu gaccagugugcgg augau aacuacugacg aa agagucaucgacuc aguuagugguu ggau guaguc acauuag uuugccucuc

>DIO2_SECIS_musMus Mus musculus (mouse) score: 29.14
cggagauguu cagagcu cacuggugugcga augau aacuacugacg aa agagcugucugcuc agucugugguu ggau guagucacac gagucug ccuuucugca

>DIO2_SECIS_ratNor Rattus norvegicus (rat) score: 27.88
ccgagauguu cggagcu cacuggugugcga augau aacuacugacg aa agagucaucugcuc agucugugguu ggau guagucacac gagucug ccucuccauc

>DIO2_SECIS_canFam Canis familiaris (dog) score: 27.29
cugggaugug cagaggu gaccagugugcga augau aacuacugaug aa agagucacugacuc aguuagugguu ggau aca gucacau uaguuuuccu

>DIO2_SECIS_dasNov Dasypus novemcinctus (armadillo) score: 26.93
cugggaaguu cagaggc uaccagugugcca augau aacuacugacg aa agaggcaucgacuc aguuagugguu ggau gua gccacau uaguuugccu

>DIO2_SECIS_monDom Monodelphis domestica (opossum) score: 28.86
guguggaagg gcugcca gugugcaa augau gaucucuaaca aa agagucagucacuc cguuagagguu ggau gugg ucacagu ggcuugcugc

>DIO2_SECIS_ornAna Ornithorhynchus anatinus (platypus) score: 24.54
ccaggauagg gcugagu uacuagugugcaa augaa gaccaccaaca aa agagaauuuaacuc aguuggugcuc agau auc aucacac uggcuuacuu

>DIO2_SECIS_anoCar Anolis carolinensis (lizard) score: 27.11
ugaggaugaa gcagagc uguuggugucuuu augaa gaucaccaaca aa agagugucucauuc aguugguguuc agau gucuua gcacug gcauuucucu

>DIO2_SECIS_galGal Gallus gallus (chicken) score: 24.57
ggggugaaac cugaaug cuuguguguuu augaa gagcacuaaca aa agaguaauugacuc aguugguguuc agau acucuca cacugg cauuccucug

DIO3: 10 SECIS insertion sequences

>DIO3_SECIS_homSap Homo sapiens (human) score: 31
uugggugcac aggagcc ccacugcug augac gaacuaucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaagcagca

>DIO3_ panTro Pan troglodytes (chimp) score 30.95
uugggugcac aggagcc ccacugcug augac gaacuaucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaagcagca

>DIO3_SECIS_macMul Macaca mulatta (rhesus) score: 30 
uugggugcac aggagcc ccacugcug augac gaacugucucu aa cuggucuugacca cgagcuaguuc ugaa uugca ggggccu caaaacagca

>DIO3_SECIS_musMus Mus musculus (mouse) score: 26 
gugcgcugga gcccugg cugcug augac gaaccgccucu aa cugggcuugaccac gggucggcuc ugaa uugca gagaggc ucgaaacagc

>DIO3_SECIS_ratNor Rattus norvegicus (rat) score: 26 
gugcgcugga gcccugg cugcug augac gaaccgccucu aa cugggcuugaccac gggucggcuc ugaa uugca gagaggc ucgaaacagc

>DIO3_ cavPor Cavia porcellus (guinea pig) score 24.06
uguuuugggc gcgcaug agccccucugcug augac gaacugucccu aa cuggucucgacc acgggcggguu ccgaa auug caggaug gcucgaaucg

>DIO3_ canFam Canis familiaris (dog) score 25.84
uauuuugggu gcuggcg agccccacugcug augac gagccgccucu aa cuggucuugacca cgagcugguuc ugag uugcagggg ggcuugc agcggcgccu

>DIO3_ felCat Felis catus (cat) score 29.2
cauuuggggu gcucacg agccccacugcug augac gagcuaucucu aa cuggucuugacca cgagcugguuc ugaa ccgc agggggc uugcagcagc

>DIO3_ bosTau Bos taurus (cow) score 23.46
uauuuugggu gcucacg agccccacugcug augaa gagcugucucu aa cuggccucgacca cgagcugguuc ugau uugc aggaggc ucgcagcagc

>DIO3_ loxAfr Loxodonta africana (elephant) score 21.95
uguuuucggu gcgcuag agccccacugcug augac gaacugucucu aa cuggucuugaccac gagcugauuc cgaa uugcagggaa cucgcagc agcgccuaaa

SELM2: 16 non-canonical SECIS insertion sequences

>SELM2_homSap Homo sapiens (human) score: non-canonical 
ggggacgggcatcggctctcagcaagagaagtattcccgggatgctgagcgcttcattctgtctcc 

>SELM2_panTro Pan troglodytes (chimp) score: non-canonical 
ggggacgggcatcggctctcagcaagagaagtattcccgggatgctgagcgcttcattctgtctcc 

>SELM2_macMul Macaca mulatta (rhesus) score: non-canonical 
ggggacggggcatcggccctcagcaagagaggtattcccgggatgctgagcgcttcattctgtctcc 

>SELM2_tupBel Tupaia belangeri (tree_shrew) score: non-canonical 
ggggacagcacatcggcccccagcaagggaggtgctcccgggatgctgagcgcttcattcggtctcc 

>SELM2_musMus Mus musculus (mouse) score: non-canonical 
ggagactggcgtcggccctcagcaagggagatgctcccgggatactgagcgcttcattctgtctcc 

>SELM2_ratNor Rattus norvegicus (rat) score: non-canonical 
ggagaccggcgtcggccctcagcaagagagtttatgctcccgggatgctgagcgcttcattctgtctcc 

>SELM2_cavPor Cavia porcellus (guinea pig) score: non-canonical 
agacgggcatcggtcctcagcaagggagatgctcccgggatgctgagcacttcattcggtcttc 

>SELM2_oryCun Oryctolagus cuniculus (rabbit) score: non-canonical 
ggggacggggcgtcggccctcagcaagggagggggctcccgggatgctgagcgcttcatcgtgtctccc 

>SELM2_sorAra Sorex araneus (shrew) score: non-canonical 
ggggacggggcgtcgaccctcagcgagggagtgctcccgggacactgagggcttcattctgtcccc 

>SELM2_canFam Canis familiaris (dog) score: non-canonical 
tgggacgaggcatcggccctcagcgagggagacgctcccgggacgctgagcgcttcattctgtcccc 

>SELM2_felCat Felis catus (cat) score: non-canonical 
tgggacggggcgtcggccctcagcgagggaggtgttcccgggacgctgagcgcttcattctgtcccc 

>SELM2_equCab Equus caballus (horse) score: non-canonical 
cgggaccgagcgtcggccctcagcgagggaggtgctcccgggacgctgaacgcttcattctgtcccc 

>SELM2_bosTau Bos taurus (cow) score: non-canonical 
ggggacggggcgtcggccctcaacgagggaggtgctcccgggccgctgagcgcttcattctgtcccc 

>SELM2_dasNov Dasypus novemcinctus (armadillo) score: non-canonical 
taggacagggcgtcggccctcagcgagggagatgctcccgggccgctgagcgcttcattcggtcccc 

>SELM2_anoCar Anolis carolinensis (lizard) score: non-canonical 
agggacgctgtctatccaccctcggcggcaagagctttcgtccgagggcttcatcctgtcccg 

MSRB2: 0 SECIS insertion sequences (lack selenocysteine)

MSRB3: 0 SECIS insertion sequences (lack selenocysteine)

GPX5: 0 SECIS sequences (cysteine all species)

GPX7: 0 SECIS sequences (all species have cysteine)

GPX8: 0 SECIS sequences (all species have cysteine or serine)

SELU1: 0 SECIS sequences (none in vertebrates)

SELU2: 0 SECIS sequences (none in vertebrates)

SELU3: 0 SECIS sequences (none in vertebrates)

SEPHS1: 0 SECIS sequences (none in vertebrates)