Selenoprotein evolution: update blog

This cluster of genomeWiki articles on selenoprotein evolution in vertebrates is updated regularly by various contributers. Because those changes can be scattered across diverse long articles, this simple directory to articles and significant updates can be helpful for following developments.

• Tracking significant updates (this page)
• Introduction to Selenoprotein evolution and curated sequence collection
• [SELU: Three "honorary" mammalian selenoproteins with UxxC motif through monotremes]
• [DIO123: Iodothyronine deiodinases: CxU motif, weak homology]
• [SEPHS1 and SEPHS2: selenophosphate synthetases]
• [SELV and SELW: an odd pair with motif CxxU]
• [MSRB methionine-R-sulfoxide reductases: a selenoprotein and 2 relic SxxU]
• [GPX1-6 Six glutathione peroxidases]
• [SELH: a new selenoprotein with motif CxxU]
• [SELI: remote paralog to CHPT cholinephosphotransferase, near-terminal U motif]
• [SELK: short Selenoprotein heat shock protein with terminal U, no C motif]
• [SELM2: new paralog of SEP15 with motif CxxU]
• [SELN: Selenoprotein N, UxxC and CU motifs]
• [SELO: large Selenoprotein with terminal CxxU]
• [SELS: another protein with penultimate U no C motif]
• [SELT, function unknown, extremely conserved, motif CxxU]
• [Other new selenoproteins]

Reverse Chronological Update Blog

06 May 08 (Tom): Added special section on basal jawless vertebrates: 16 genes from lamprey, 6 from hagfish.
28 Apr 08 (Tom): Brought total sequence count to 341, greatly expanded DIO1 and SELV collections and gene hightlights
25 Apr 08 (Tom): Fixed DIO deiodinase sequences
24 Apr 08 (Tom): Added echidna and platypus selenoproteins from 454 search
23 Apr 08 (Tom): Added and analyzed 13 boreoeuthere SELV sequences
20 Apr 08 (Tom): Selenoprotein wiki launch
16 Apr 08 (Tom): Platypus and echidna selenoproteins from 454 transcripts
15 Apr 08 (Tom): SELU and SEPW1 updated to 50 vertebrate genome projects