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PRDM11 is a much older gene than PRDM7/9, one that arose in early bony vertebrates and persisted in all descendent lineages including human. Its d ...junction has been conserved for many billions of years of branch length in bony vertebrates. It contains two well-established Pfam domains proving that it

| Bony fishes | Bony fishes

=== Duplicated DHFRL2 in bony vertebrates === ...rms a distinct, more diverged cluster that branches off from DHFR in early bony vertebrates.

...gram at left provides a composite view of relative degree of divergence of bony vertebrates from their common outgroup chondrichthyes (which contributes a

It is easy to compile large sets of bony vertebrate exons for these three genes using the 44-species genomic alignme