User:Ling-Ling Chen

Address: Institute of Biochemistry and Cell Biology

               Shanghai Institutes for Biological Sciences
               Chinese Academy of Sciences
               320 Yueyang Road, Shanghai, 200031 China 

E-mail: linglingchen@sibcb.ac.cn

EDUCATION 2004 – 2009 Ph.D. (Biomedical Science), University of Connecticut Health Center, Farmington, CT, USA 2007 – 2009 M.B.A. (Management), University of Connecticut, Hartford, CT, USA 2000 – 2003 M.S. (Pharmacology), Chinese Academy of Science, Shanghai, China 1996 – 2000 B.S. (Biology), Lanzhou University, Gansu, China

POSITIONS 02/2011 – present PI, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences, China 05/2010 – 01/2011 Assistant Professor, Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT, USA 04/2009 – 03/2010 Post-Doc Fellow, Stem Cell Institute, University of Connecticut Health Center, Farmington, CT, USA 09/2004 – 02/2009 Ph.D. student, University of Connecticut Health Center, Farmington, CT, USA 09/2007 – 04/2009 MBA student, University of Connecticut, Hartford, CT, USA.

RESEARCH SUPPORT Chinese Academy of Sciences for Stem Cell Research (01/2011 – 12/2016) Ministry of Science and Technology 973 project, 2011CBA01105 (01/2011 – 12/2016) State of Connecticut Stem Cell Seed Award, 09SCAUCHC16 (06/2009 – 05/2011)

SELECTED PUBLICATIONS Chen LL* and Carmichael GG. Nuclear editing of mRNA 3’-UTRs. (2011) Curr. Top. Microbiol. Immunol. Jul 3. [Epub ahead of print]. (* Corresponding author) Yang L, Duff MO, Graveley BR, Carmichael GG and Chen LL*. Genomewide characterization of non-polyadenylated RNAs. (2011) Genome Biol. 12: R16. (* Corresponding author) Peng S, Chen LL, Chen F, Lei XX, Yang L, Qiu C, Lin H, Carmichael GG, Huang Y. Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. (2011) Stem Cells. 29: 496-504. Chen LL*, Yang L and Carmichael GG*. Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells. (2010) Cell Cycle. 9:3552-3564. (* Corresponding author) Chen LL* and Carmichael GG. Long non-coding RNAs in mammalian cells: What, Where and Why? (2010) WIREs RNA. 1: 2-21. (* Corresponding author) Chen LL* and Carmichael GG*. Decoding the function of nuclear long non-coding RNAs. (2010) Curr. Opin. Cell Biol. 22: 357-364. (* Corresponding author) Chen LL and Carmichael GG. Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA. (2009) Mol Cell. 35: 467-478. Chen LL and Carmichael GG†. Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats. (2008) Cell Cycle. 7: 3297-3301. Chen LL, Decerbo JN and Carmichael GG. Alu element-mediated gene silencing. (2008) EMBO J. 27: 1694-1705. Zhou J, Wang Q, Chen LL and Carmichael GG. On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin. (2008) RNA 14: 1773-1781.