T-cell epitope databases and algorithms: Difference between revisions

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Revision as of 04:08, 19 May 2014

The most difficult problem in the study of T-Cells is to figure out

  1. which peptides are displayed by the cell and
  2. which T-Cell receptor binds to which peptide

Databases of peptides:

  • HSPV: Big list of peptides derived from RefSeq and dbSNP, not annotated at all
  • Ludwig CancerImmunomeDB: database of cDNA clones, some which annotated to react to serum

Algorithms to predict which peptides are displayed: